チミジン一リン酸、デオキシチミジン一リン酸
- 関
- dTMP、thymidine monophosphate、thymidylate
WordNet
- a nucleoside component of DNA; composed of thymine and deoxyribose (同)thymidine
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/23 11:20:46」(JST)
[Wiki en表示]
Thymidine monophosphate |
|
|
Identifiers |
Abbreviations |
TMP |
PubChem |
16755631 |
ChemSpider |
10239189 Y |
ChEBI |
CHEBI:26999 Y |
ChEMBL |
CHEMBL394429 N |
Beilstein Reference |
3916216 |
Jmol-3D images |
Image 1 |
-
Cc1cn(C2CC(O)C(COP([O-])([O-])=O)O2)c(:o)[nH]c1:o
|
-
InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/p-2 N
Key: GYOZYWVXFNDGLU-UHFFFAOYSA-L N
|
Properties |
Molecular formula |
C10H13N2O8P1- |
Molar mass |
322.2085 g mol-1 |
N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Infobox references |
Thymidine monophosphate, also known as 5'-thymidylate, thymidylate, or TMP, is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. TMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine monophosphate does not contain the "deoxy" prefix in its name.[1] As a substituent, it takes the form of the prefix thymidylyl-.
See also[edit]
- Nucleoside
- Nucleotide
- DNA
- RNA
- Oligonucleotide
References[edit]
- ^ Coghill, Anne M.; Garson, Lorrin R., ed. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
External links[edit]
Nucleic acid constituents
|
|
Nucleobase |
Purine (Adenine, Guanine, Hypoxanthine, Xanthine, Purine analogue) · Pyrimidine (Uracil, Thymine, Cytosine, Pyrimidine analogue)
|
|
Nucleoside |
Ribonucleoside
|
Adenosine · Guanosine · 5-Methyluridine · Uridine · Cytidine · Inosine · Xanthosine
|
|
Deoxyribonucleoside
|
Deoxyadenosine · Deoxyguanosine · Thymidine · Deoxyuridine · Deoxycytidine · Deoxyinosine · Deoxyxanthosine
|
|
|
Nucleotide
(Nucleoside monophosphate) |
Ribonucleotide
|
AMP, GMP, m5UMP, UMP, CMP, IMP, XMP
|
|
Deoxyribonucleotide
|
dAMP, dGMP, dTMP, dUMP, dCMP, dIMP, dXMP
|
|
Cyclic nucleotide
|
cAMP, cGMP, c-di-GMP, cADPR
|
|
|
Nucleoside diphosphate |
ADP, GDP, m5UDP, UDP, CDP
dADP, dGDP, dTDP, dUDP, dCDP
|
|
Nucleoside triphosphate |
ATP, GTP, m5UTP, UTP, CTP, ITP, XTP
dATP, dGTP, dTTP, dUTP, dCTP, dITP, dXTP
|
|
- Biochemical families: carbohydrates
- alcohols
- glycoproteins
- glycosides
- lipids
- eicosanoids
- fatty acids / intermediates
- phospholipids
- sphingolipids
- steroids
- nucleic acids
- constituents / intermediates
- proteins
- Amino acids / intermediates
- tetrapyrroles / intermediates
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.
- Komazin-Meredith G1, Cardinale SC2, Comeau K2, Magalhaes KJ2, Hartline CB3, Williams JD2, Opperman TJ2, Prichard MN3, Bowlin TL2.
- Antiviral research.Antiviral Res.2015 Jul;119:23-7. doi: 10.1016/j.antiviral.2015.04.001. Epub 2015 Apr 7.
- Monohydroxymethyl methylenecyclopropane nucleosides (MCPNs) with ether or thioether substituents at the 6-position show promise as broad-spectrum herpes virus inhibitors. Their proposed mechanism of action involves sequential phosphorylation to a triphosphate, which can then inhibit viral DNA polyme
- PMID 25857706
- Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones.
- Skouloubris S1, Djaout K2, Lamarre I2, Lambry JC2, Anger K3, Briffotaux J2, Liebl U2, de Reuse H3, Myllykallio H4.
- Open biology.Open Biol.2015 Jun;5(6). pii: 150015. doi: 10.1098/rsob.150015.
- ThyX is an essential thymidylate synthase that is mechanistically and structurally unrelated to the functionally analogous human enzyme, thus providing means for selective inhibition of bacterial growth. To identify novel compounds with anti-bacterial activity against the human pathogenic bacterium
- PMID 26040760
- Kinetico-Mechanistic Studies of Nucleoside and Nucleotide Substitution Reactions of Co(III) Complexes of Fully Alkylated Cyclen.
- Martínez M1, Vázquez M1.
- Inorganic chemistry.Inorg Chem.2015 May 18;54(10):4972-80. doi: 10.1021/acs.inorgchem.5b00581. Epub 2015 May 6.
- The solution chemistry of complex [Co{(Me)2(μ-ET)cyclen}(H2O)2](3+) containing a fully substituted tetraammine ligand designed for the avoidance of base-conjugated substitution mechanisms in the 6-8 pH range has been studied. The study should shed some light on the possible involvement of such Co(I
- PMID 25943135
Japanese Journal
- STIMULATION OF PHOSPHOLIPASE C-MEDIATED HYDROLYSIS OF PHOSPHOINOSITIDES BY ADENOSINE 5'-TRIPHOSPHATE VIA P_2-PURlNOCEPTORS IN CULTURED RAT AORTIC VASCULAR SMOOTH MUSCLE CELLS
- Stimulation of phospholipase C-mediated hydrolysis of phosphoinositides by adenosine 5'-triphosphate via P2-purinoceptors in cultured rat aortic vascular smooth muscle cells.
- Degradation of Nucleic Acids with Ozone. V. Mechanism of Action of Ozone on Deoxyribonucleoside 5'-Monophosphates
Related Links
- Thymidine monophosphate, also known as 5'-thymidylate, thymidylate, or TMP, is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. TMP consists of a phosphate group, the pentose ...
Related Pictures
★リンクテーブル★
[★]
- 英
- thymidine monophosphate, TMP
- 同
- チミジル酸 thymidylic acid thymidylate
- 関
- (DNA)デオキシチミジン一リン酸 deoxythymidine monophosphate dTMP
[★]
チミジル酸、チミジン一リン酸
- 関
- deoxythymidine monophosphate、dTMP、thymidine monophosphate、thymidylic acid
[★]
- 英
- deoxythymidine monophosphate、dTMP
- 関
- チミジル酸、チミジン一リン酸
[★]
チミジン、デオキシチミジン
- 関
- dT、thymidine
[★]