cytoplasmic retinoic acid-binding protein

• 細胞質レチノイン酸結合タンパク質、細胞内レチノイン酸結合タンパク質

関

cellular retinoic acid-binding protein、CRABP

WordNet

1. executed with proper legal authority; "a binding contract"
2. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
3. strip sewn over or along an edge for reinforcement or decoration
4. the capacity to attract and hold something
5. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
6. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
7. having the characteristics of an acid; "an acid reaction"
8. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
9. of or relating to cytoplasm (同)cytoplasmatic
10. the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism (同)cytol

PrepTutorEJDIC

1. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
2. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
3. 蛋白(たんばく)質
4. 細胞質の
5. 細胞質

UpToDate Contents

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• 1. 急性前骨髄球性白血病の分子生物学 molecular biology of acute promyelocytic leukemia
• 2. 急性骨髄性白血病の分子遺伝学 molecular genetics of acute myeloid leukemia
• 3. 再発性および難治性の急性前骨髄球性白血病の治療 treatment of relapsed or refractory acute promyelocytic leukemia in adults
• 4. 骨髄造血の制御 regulation of myelopoiesis
• 5. 急性骨髄性白血病における細胞遺伝学 cytogenetics in acute myeloid leukemia

English Journal

• Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins.

• Doldo E1, Costanza G1, Agostinelli S1, Tarquini C1, Ferlosio A1, Arcuri G1, Passeri D1, Scioli MG1, Orlandi A1.
• BioMed research international.Biomed Res Int.2015;2015:624627. doi: 10.1155/2015/624627. Epub 2015 Mar 24.
• Retinol and vitamin A derivatives influence cell differentiation, proliferation, and apoptosis and play an important physiologic role in a wide range of biological processes. Retinol is obtained from foods of animal origin. Retinol derivatives are fundamental for vision, while retinoic acid is essen
• PMID 25879031

• Cellular retinoic acid-binding protein 2 inhibits tumor growth by two distinct mechanisms.

• Vreeland AC1, Levi L1, Zhang W1, Berry DC2, Noy N3.
• The Journal of biological chemistry.J Biol Chem.2014 Dec 5;289(49):34065-73. doi: 10.1074/jbc.M114.604041. Epub 2014 Oct 15.
• Cellular retinoic acid-binding protein 2 (CRABP2) potently suppresses the growth of various carcinomas, but the mechanism(s) that underlies this activity remains incompletely understood. CRABP2 displays two distinct functions. The classical function of this protein is to directly deliver retinoic ac
• PMID 25320093

• SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.

• Tang S1, Huang G2, Fan W3, Chen Y4, Ward JM5, Xu X5, Xu Q6, Kang A7, McBurney MW8, Fargo DC5, Hu G9, Baumgart-Vogt E3, Zhao Y4, Li X10.
• Molecular cell.Mol Cell.2014 Sep 18;55(6):843-55. doi: 10.1016/j.molcel.2014.07.011. Epub 2014 Aug 21.
• Retinoid homeostasis is critical for normal embryonic development. Both the deficiency and excess of these compounds are associated with congenital malformations. Here we demonstrate that SIRT1, the most conserved mammalian NAD⁺-dependent protein deacetylase, contributes to homeostatic retinoic ac
• PMID 25155613

Japanese Journal

• レチノイン酸,Am80による急性前骨髄球性白血病の治療--急性前骨髄球性白血病に対する全トランス型レチノイン酸と合成レチノイドAm80の標準的な治療と発展性 (第1土曜特集 造血器腫瘍の分子標的療法) -- (標準的治療にみる分子標的療法)

• 竹下 明裕
• 医学のあゆみ 220(9), 681-686, 2007-03-03
• NAID 40015287584

Related Links

• Structure/function of cytoplasmic vitamin A-binding proteins.

Two cytoplasmic retinol-binding proteins, CRBP and CRBP II, and two cytoplasmic retinoic acid-binding proteins, CRABP-I and CRABP-II, have been well characterized. There has been significant progress in the structural analysis of these ...

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★リンクテーブル★

リンク元	「CRABP」「細胞内レチノイン酸結合タンパク質」「細胞質レチノイン酸結合タンパク質」「cellular retinoic acid-binding protein」
関連記事	「binding」「cytoplasmic」「binding protein」

「CRABP」

　　[★]

• 細胞内レチノイン酸結合タンパク質、細胞質レチノイン酸結合タンパク質

関

cellular retinoic acid-binding protein、cytoplasmic retinoic acid-binding protein

「細胞内レチノイン酸結合タンパク質」

　　[★]

英

cellular retinoic acid-binding protein、cytoplasmic retinoic acid-binding protein、CRABP

関

細胞質レチノイン酸結合タンパク質

「細胞質レチノイン酸結合タンパク質」

　　[★]

英

cytoplasmic retinoic acid-binding protein、CRABP

関

細胞内レチノイン酸結合タンパク質

「cellular retinoic acid-binding protein」

　　[★]

• 細胞内レチノイン酸結合タンパク質

関

CRABP、cytoplasmic retinoic acid-binding protein

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「cytoplasmic」

　　[★]

• 細胞質の、細胞質内の、細胞質側の、原形質の

関

cytoplasm、cytoplasma、intracytoplasmic、protoplasm、protoplasmic

　 　

「binding protein」

　　[★]

• 結合タンパク質、結合タンパク、結合蛋白質、結合蛋白

関

BP、carrier protein、transport protein