Electron transfer followed by collision-induced dissociation (NET-CID) for generating sequence information from backbone-modified oligonucleotide anions.
Gao Y, McLuckey SA.SourceDepartment of Chemistry, Purdue University, West Lafayette, IN, 47907-2084, USA.
Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2013 Jan 15;27(1):249-57. doi: 10.1002/rcm.6428.
RATIONALE: Oligonucleotides with 2'-modifications and/or phosphorothioate (PS) backbones are prone to undergo limited backbone fragmentation upon ion trap collision-induced dissociation (CID). For better identification and characterization of chemically modified oligonucleotides, a more universal fr
Comparison of the LTQ-Orbitrap Velos and the Q-Exactive for proteomic analysis of 1-1000 ng RAW 264.7 cell lysate digests.
Sun L, Zhu G, Dovichi NJ.SourceDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2013 Jan 15;27(1):157-62. doi: 10.1002/rcm.6437.
RATIONALE: There is interest in extending bottom-up proteomics to the smallest possible sample size. We investigated the performance of two modern mass spectrometers for the analysis of samples ranging from 1 ng to 1 µg of RAW 264.7 cell lysate digests.METHODS: An ultra-performance liquid chrom
Confident identification of isomeric N-glycan structures by combined ion mobility mass spectrometry and hydrophilic interaction liquid chromatography.
Yamaguchi Y, Nishima W, Re S, Sugita Y.SourceStructural Glycobiology Team, Systems Glycobiology Research Group, Chemical Biology Department, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan. email@example.com.
Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2012 Dec 30;26(24):2877-84. doi: 10.1002/rcm.6412.
RATIONALE: A central issue in glycan mass analysis is the ambiguity of structural assignments due to the heterogeneity and complexity of glycan structures. Ion mobility mass spectrometry (IM-MS) has the potential to separate isomeric glycans depending on their unique collisional cross section especi
Holdren's knowledge and involvement in fusion goes back to the early 1970s, when he published a paper "Analytic Approximation to Collisional Distribution in Mirror Plasmas" while working in the magnetic fusion energy program at the ...