マイコプラズマ肺炎。寒冷凝集反応陽性肺炎
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- 1. 成人における市中肺炎に対する診断的アプローチdiagnostic approach to community acquired pneumonia in adults [show details]
…confirmed by a positive sputum culture in 36 of the 44 patients (82 percent). Urinary pneumococcal antigen test was positive in 52 of the 97 (54 percent) patients with pneumococcal pneumonia. Blood cultures …
- 2. 成人に生じる市中肺炎の概要overview of community acquired pneumonia in adults [show details]
… Nosocomial pneumonia refers to an acute infection of the pulmonary parenchyma acquired in hospital settings and encompasses both hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP). …
- 3. 細菌性肺炎の評価のための喀痰培養sputum cultures for the evaluation of bacterial pneumonia [show details]
… data in patients suspected of having nosocomial pneumonia, especially those who are intubated. In patients suspected of having nosocomial pneumonia, a positive sputum culture in association with the typical …
- 4. 人工呼吸器関連肺炎の臨床症状と診断clinical presentation and diagnostic evaluation of ventilator associated pneumonia [show details]
… analysis are negative but may be positive for malignant cells. Lung biopsy may be necessary. Radiation pneumonitis – Radiation-induced lung injury may cause acute pneumonitis or chronic fibrosis. The former …
- 5. Pneumonia caused by Chlamydia pneumoniae in childrenpneumonia caused by chlamydia pneumoniae in children [show details]
… days; if it is performed on site, turnaround time is usually three to four hours. Positive results for C. pneumoniae should be correlated with clinical findings because PCR-based assays do not differentiate …
English Journal
- Combined vaccines for prophylaxis of infectious conditions.
- Shende P, Waghchaure M.
- Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)696-705.
- In recent years, the application of vaccines shows limitations, including the high number of vaccine administrations and the fear of safety and effectiveness. In this regard, advanced vaccine products have been developed, like the combined vaccines, or are under development, such as nucleic acid vac
- PMID 30829068
- Syzygium aromaticum aqueous extract inhibits human neutrophils myeloperoxidase and protects mice from LPS-induced lung inflammation.
- Chniguir A, Zioud F, Marzaioli V, El-Benna J, Bachoual R.
- Pharmaceutical biology. 2019 Dec;57(1)56-64.
- Syzygium aromaticum (L.) Merr. & Perry (Myrtaceae), commonly known as clove, originally found in the Muluku Islands in East Indonesia, is widely used as a spice and has numerous medicinal properties. This study investigated the antioxidant potential of S. aromaticum aqueous extract (SAAE) in vitro a
- PMID 30707845
- Contagious caprine pleuropneumonia - a comprehensive review.
- Iqbal Yatoo M, Raffiq Parray O, Tauseef Bashir S, Ahmed Bhat R, Gopalakrishnan A, Karthik K, Dhama K, Vir Singh S.
- The Veterinary quarterly. 2019 Dec;39(1)1-25.
- Contagious caprine pleuropneumonia (CCPP) is a serious disease of goats, occasionally sheep and wild ruminants, caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp). The disease is characterized by severe serofibrinous pleuropneumonia, very high morbidity (∼100%), and mortality (80-10
- PMID 30929577
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★リンクテーブル★
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- 英
- mycoplasma pneumonia
- 同
- 寒冷凝集反応陽性肺炎 coldagglutinin-positive pneumonia、オリンピック病 Olympic disease、イートン因子肺炎
- 関
- マイコプラズマ、非定型肺炎。Mycoplasma pneumoniae
概念
- マイコプラズマは人工培地上で発育できる最小の微生物で、一般細菌と異なり細胞壁を欠く。
- Mycoplasma pneumoniaeによる肺炎
- 4年に1度オリンピックの開催年に多発する傾向がみられたためオリンピック病とも呼ばれたが、近年この傾向はあまりみられない。
- 若年者に多く、強い咳嗽と高熱が特徴である。
疫学
- 健康な小児や若年成人の肺炎でよく見られる。
- 好発年齢：5-25歳
潜伏期
感染経路
症状
- 初期には乾性咳嗽
- 発熱、激しい咳嗽、結膜充血、頭痛などを呈する。
- 喀痰が無いことが多い。
検査
- 白血球：増加することは少ない。80～90%の症例で10000/μL以下
- CRP：軽度上昇にとどまる。
- 血中寒冷凝集素価：陽性(256-512倍以上)。約50%の症例で上昇。
- 胸部XP：下肺野に陰影が多い。
- CT：非定型肺炎の陰影を呈する。間質性の炎症像を呈し網状影が主体で、次いで炎症が肺胞領域に及ぶと斑状影となり、いわゆる細葉性の陰影を示す。
診断
- CF法はIgGクラスの抗体を検出
- PA法はIgMクラスの抗体を検出
- たいていの迅速検査ではIgM抗体を検出している。
- 急性期と回復期(2～4週以降)のペア血清を用いて、特異抗体価が4倍以上の上昇を示す
治療
- テトラサイクリン、マクロライド系薬剤が有効。
- ペニシリン系抗菌薬、セフェム系抗菌薬、カルバペネム系抗菌薬は無効。
鑑別
国試
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- 関
- active、actively、aggressive、offensive、positively、positivity