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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/26 18:00:29」(JST)
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Chorioepithelioma is a malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all chorioepitheliomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Chorioepitheliomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease. Also called chorioblastoma, choriocarcinoma, and chorionic carcinoma.
External links
- Chorioepithelioma entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
English Journal
- Dexamethasone Downregulates SLC7A5 Expression and Promotes Cell Cycle Arrest, Autophagy and Apoptosis in BeWo Cells.
- He B1, Zhang N1, Zhao R1.
- Journal of cellular physiology.J Cell Physiol.2016 Jan;231(1):233-42. doi: 10.1002/jcp.25076.
- Synthetic glucocorticoids (GCs) such as dexamethasone (Dex) are widely given to pregnant women to induce maturation and improve viability of preterm infants. Despite the beneficial effects, synthetic GCs have adverse effects on placental growth and nutrient transport system. However, the molecular m
- PMID 26094588
- Human placental cell and tissue uptake of doxorubicin and its liposomal formulations.
- Soininen SK1, Repo JK2, Karttunen V2, Auriola S2, Vähäkangas KH2, Ruponen M2.
- Toxicology letters.Toxicol Lett.2015 Dec 3;239(2):108-14. doi: 10.1016/j.toxlet.2015.09.011. Epub 2015 Sep 14.
- The anticancer drug doxorubicin and its liposomal formulations are in clinical use, doxorubicin also during pregnancy. However, little is known about how doxorubicin and its liposomal formulations are taken up by placental cells and whether they can cross human placenta. We therefore investigated qu
- PMID 26383631
- Clinicopathologic Analysis of Postchemotherapy Gestational Trophoblastic Neoplasia: An Entity Overlapping With Epithelioid Trophoblastic Tumor.
- Lu B1, Zhang X, Liang Y.
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.Int J Gynecol Pathol.2015 Dec 1. [Epub ahead of print]
- Surgery is generally not required for the majority of gestational trophoblastic neoplasias (GTNs) because they are potentially curable by chemotherapy alone. The histologic assessment is rarely available although the identification of a specific subtype of GTN is relevant to clinical intervention an
- PMID 26630228
Japanese Journal
- Alpha-fetoprotein, human choriogonadotropine 産生巨大胃癌の1例
- Alpha‐fetoprotein, human choriogonadotropine産生巨大胃癌の1例
Related Links
- Don (SB), also known as Ban-Zhi-Lian (barbat sskullcap) in traditional Chinese medicine, is a medicinal herb that has long been used as an antitumor agent for lung cancer, digestive system cancer, hepatoma, breast cancer, and chorioepithelioma ...
- Chorioepithelioma definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! Thesaurus Translate Puzzles & Games Word of the Day Blog Slideshows Apps by Dictionary ...
Related Pictures
★リンクテーブル★
[★]
- chorio
- 英
- choriocarcinoma
- 同
- 絨毛上皮腫 chorioepithelioma
- 関
- 悪性合胞体腫、絨毛疾患
疫学
- 日本、東南アジア、中東、ラテンアメリカに多い
- 人口10万人にたいして年間0.05人
- 正常妊娠からは5-10万例に1例、全胞状奇胎の1-2%に発症、部分胞状奇胎では稀とされる(G9M.184)
病理
- NGY.242
- 組織構造:絨毛構造無し。破壊的増殖。出血、壊死。
- 細胞形態:細胞性、合胞体、中間型栄養膜細胞に類似した細胞。破壊的な増殖像。細胞異型あり
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転移
治療
-
- 手術療法:子宮、肺の病変に関しては適応となることがある。
- 放射線療法:脳、肝臓に対して行われる。
参考
- 1. [charged]Malignant gestational trophoblastic disease: Staging and treatment - uptodate
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国試
[★]
- 英
- chorioepithelioma
- 関
- 絨毛癌