- 関
- cTnC
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- of or relating to the heart; "cardiac arrest"
- the opening into the stomach and that part of the stomach connected to the esophagus
PrepTutorEJDIC
- carbonの化学記号
- 心臓の
- cesiumの化学記号
- cadmiumの化学記号
UpToDate Contents
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- 1. 拡張型心筋症の遺伝学 genetics of dilated cardiomyopathy
- 2. 心筋における興奮収縮連関 excitation contraction coupling in myocardium
- 3. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
English Journal
- The cardiac-specific N-terminal region of troponin I positions the regulatory domain of troponin C.
- Hwang PM1, Cai F2, Pineda-Sanabria SE2, Corson DC2, Sykes BD2.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Sep 22. pii: 201410775. [Epub ahead of print]
- The cardiac isoform of troponin I (cTnI) has a unique 31-residue N-terminal region that binds cardiac troponin C (cTnC) to increase the calcium sensitivity of the sarcomere. The interaction can be abolished by cTnI phosphorylation at Ser22 and Ser23, an important mechanism for regulating cardiac con
- PMID 25246568
- Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery.
- Pineda-Sanabria SE1, Julien O, Sykes BD.
- ACS chemical biology.ACS Chem Biol.2014 Sep 19;9(9):2121-30. doi: 10.1021/cb500249j. Epub 2014 Jul 17.
- Investigation of the molecular interactions within and between subunits of the heterotrimeric troponin complex, and with other proteins in the sarcomere, has revealed salient structural elements involved in regulation of muscle contraction. The discovery of new cardiotonic drugs and structural studi
- PMID 25010113
- PKA Phosphorylation of Cardiac Troponin I Modulates Activation and Relaxation Kinetics of Ventricular Myofibrils.
- Rao V1, Cheng Y2, Lindert S3, Wang D1, Oxenford L1, McCulloch AD4, McCammon JA5, Regnier M6.
- Biophysical journal.Biophys J.2014 Sep 2;107(5):1196-204. doi: 10.1016/j.bpj.2014.07.027.
- Protein kinase A (PKA) phosphorylation of myofibril proteins constitutes an important pathway for β-adrenergic modulation of cardiac contractility and relaxation. PKA targets the N-terminus (Ser-23/24) of cardiac troponin I (cTnI), cardiac myosin-binding protein C (cMyBP-C) and titin. The effect of
- PMID 25185555
Japanese Journal
- Use of a new high-sensitivity assay for cardiac troponin T to stratify the risk of cardiovascular disease in outpatients with type-2 diabetes
- ASANO Shogo,SUZUKI Atsushi,ISHII Junnichi,SEKIGUCHI UEDA Sahoko,SHIBATA Megumi,YOSHINO Yasumasa,NAKAMURA Kazuhiro,AKIYAMA Yasukazu,KITAGAWA Fumihiko,SAKUISHI Toshiaki,FUJITA Takashi,ITOH Mitsuyasu
- Diabetology international 3(1), 29-36, 2013-03-01
- NAID 10030925775
- Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells(CELL AND TISSUE ENGINEERING)
- Higuchi Sayaka,Lin Qingsong,Wang Jigang,Lim Teck Kwang,Joshi Shashikant B.,Anand Ganesh Srinivasan,Chung Maxey C.M.,Sheetz Michael P.,Fujita Hideaki
- Journal of bioscience and bioengineering 115(3), 320-325, 2013-03-00
- … When mouse ES cells were cultured on thin (60 μm) sections of de-cellularized tissue, the expression of cardiac myosin heavy chain (cMHC) and cardiac troponin I (cTnI) was high in ES cells cultured on heart ECM compared with those cultured on liver ECM. …
- NAID 110009596108
- Comparative analysis of cardiomyocyte differentiation from human embryonic stem cells under 3-D and 2-D culture conditions(CELL AND TISSUE ENGINEERING)
- Pal Rajarshi,Mamidi Murali Krishna,Das Anjan Kumar,Bhonde Ramesh
- Journal of bioscience and bioengineering 115(2), 200-206, 2013-02-00
- … Post-myocardial infarction cardiomyocytes are the most important target cell types for cardiac repair. … An in-depth characterization of the beating cells revealed appropriate cardiac marker expression both at gene and protein levels. … While the expression of pre-cardiac mesoderm markers like GATA-4, HAND1, Myf5, Msx1, and BMP-IIR remained unaltered; …
- NAID 110009592572
Related Links
- Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of ...
- Troponins are protein molecules that are part of cardiac and skeletal muscle. Smooth muscle cells do not contain troponins. Three types of troponins exist—troponin I, troponin T, and troponin C. Each of the 3 troponin ...
Related Pictures
★リンクテーブル★
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- 関
- cardiac troponin C
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- 英
- cardiac troponin C、cTnC
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- 関
- cardio、cardiotonic、heart、mind
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セシウム, caesium, cesium
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カドミウム
- 関
- cadmium
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