WordNet

a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
carbonated drink with fruit syrup and a little phosphoric acid

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〈U〉リン酸塩 / 《複数形で》リン酸肥料

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/23 11:59:09」(JST)

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Carbamoyl phosphate is an anion of biochemical significance. In land-dwelling animals it is an intermediary metabolite participating in the nitrogen disposal through in the urea cycle and the synthesis of pyrimidines.

Production[edit]

It is produced from bicarbonate, ammonia (derived from glutamine), and phosphate (from ATP). The synthesis is catalysed by the enzyme carbamoyl phosphate synthetase, as follows:

HCO₃⁻ + ATP → ADP + HO–C(O)–OPO₃²⁻ (carboxyl phosphate)
HO–C(O)–OPO₃²⁻ + NH₃ + OH⁻ → HPO₄²⁻ + ⁻O–C(O)NH₂ + H₂O
⁻O–C(O)NH₂ + ATP → ADP + H₂NC(O)OPO₃²⁻

References[edit]

Nelson, David L. and Michael M. Cox. Lehninger Principles of Biochemistry fourth edition. W. H. Freeman and company New York.

UpToDate Contents

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1. カルシウムおよびリン酸バランスの調節 regulation of calcium and phosphate balance
2. 高リン血症の原因および治療の概要 overview of the causes and treatment of hyperphosphatemia
3. グルコース-6-リン酸脱水素酵素欠損症の診断および治療 diagnosis and treatment of glucose 6 phosphate dehydrogenase deficiency
4. 慢性腎疾患における高リン血症の治療 treatment of hyperphosphatemia in chronic kidney disease
5. 低リン血症の評価および治療 evaluation and treatment of hypophosphatemia

English Journal

Glutaminase 1 inhibition reduces thymidine synthesis in NSCLC.

Lee JS1, Kang JH1, Lee SH1, Lee CH1, Son J2, Kim SY3.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Aug 26;477(3):374-82. doi: 10.1016/j.bbrc.2016.06.095. Epub 2016 Jun 23.
We found that non-small cell lung cancer (NSCLC) is remarkably sensitive to the regulation of glutamine supply by testing the metabolic dependency of 11 cancer cell lines against regulation of glycolysis, autophagy, fatty acid synthesis, and glutamine supply. Glutamine is known as a key supplement o
PMID 27338638

DIFFERENTIAL PROTEOME ANALYSIS OF THE MALE AND FEMALE ANTENNAE FROM Holotrichia parallela.

Zhang JH1, Wang S1, Yang S1, Yi J1, Liu Y1, Xi JH1.
Archives of insect biochemistry and physiology.Arch Insect Biochem Physiol.2016 Aug;92(4):274-87. doi: 10.1002/arch.21338. Epub 2016 Jul 11.
To understand the olfactory mechanisms of Holotrichia parallela antennae in detecting volatile compounds in the environment, protein profiles of H. parallela antennae were analyzed using two-dimensional electrophoresis followed by mass spectrometry and bioinformatics analyses. Approximately 1,100 pr
PMID 27396371

Inhibitors of alanine racemase enzyme: a review.

Azam MA1, Jayaram U1.
Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2016 Aug;31(4):517-26. doi: 10.3109/14756366.2015.1050010. Epub 2015 May 29.
Alanine racemase is a fold type III PLP-dependent amino acid racemase enzyme catalysing the conversion of l-alanine to d-alanine utilised by bacterial cell wall for peptidoglycan synthesis. As there are no known homologs in humans, it is considered as an excellent antibacterial drug target. The stan
PMID 26024289

Japanese Journal

Elimination and active extrusion of liver mitochondrial proteins during lipopolysaccharide administration in rat

UNUMA Kana,AKI Toshihiko,MATSUDA Seiji,FUNAKOSHI Takeshi,YOSHIDA Ken-ichi,UEMURA Koichi
Hepatology research : the official journal of the Japan Society of Hepatology 43(5), 526-534, 2013-05-01
NAID 10031183486

Little gene flow between domestic silkmoth Bombyx mori and its wild relative Bombyx mandarina in Japan, and possible artificial selection on the CAD gene of B. mori

Yukuhiro Kenji,Sezutsu Hideki,Tamura Toshiki [他],Kosegawa Eiichi,Iwata Kazuya,Ajimura Masahiro,Gu Shi-Hong,Wang Min,Xia Qingyou,Mita Kazuei,Kiuchi Makoto
Genes & Genetic Systems 87(5), 331-340, 2012
… We analyzed PCR-amplified carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) gene fragments from 146 Bombyx mori native strains and found extremely low levels of DNA polymorphism. …
NAID 130003360984

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★リンクテーブル★

リンク元	「カルバモイルリン酸」「carbamyl phosphate」
拡張検索	「carbamoyl-phosphate synthase」「glutamine-hydrolyzing carbamoyl-phosphate synthase」「carbamoyl-phosphate synthase I」「carbamoyl phosphate synthetase」「carbamoyl-phosphate synthetase」
関連記事	「phosphate」

「カルバモイルリン酸」

Carbamoyl phosphate
	IUPAC name (Carbamoyloxy)phosphonic acid
Identifiers
CAS number	590-55-6
PubChem	278
ChemSpider	272
KEGG	C00169
MeSH	Carbamoyl+phosphate
ChEBI	CHEBI:17672
ChEMBL	CHEMBL369105
Jmol-3D images	Image 1
	SMILES C(=O)(N)OP(=O)(O)O ;
	InChI InChI=1S/CH4NO5P/c2-1(3)7-8(4,5)6/h(H2,2,3)(H2,4,5,6); Key: FFQKYPRQEYGKAF-UHFFFAOYSA-N ;
Properties
Molecular formula	CH2NO5P2−
Molar mass	141.020 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references