出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/06/19 07:15:12」(JST)
Anterior chamber of eyeball | |
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Anterior part of human eye, with anterior chamber at right.
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Schematic diagram of the human eye.
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Details | |
Identifiers | |
Latin | camera anterior bulbi oculi |
TA | A15.2.06.003 |
FMA | 58078 |
Anatomical terminology
[edit on Wikidata]
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The anterior chamber (AC) is the fluid-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium.[1] Aqueous humor is the fluid that fills the anterior chamber. Hyphema, anterior uveitis and glaucoma are three main pathologies in this area. In hyphema, blood fills the anterior chamber. In glaucoma, blockage of the trabecular meshwork prevents the normal outflow of aqueous humor, resulting in accumulation of fluid, increased intraocular pressure, progressive damage to the optic nerve head, and eventually blindness. The normal depth of the anterior chamber of the eye is 3.5mm to 2.5mm; depth less than 2.5mm can be a risk factor for angle closure glaucoma.
Determining the anterior chamber depth (ACD) is important in estimating the risk of angle closure glaucoma. There are various method of measuring ACD, including examination through a slit lamp, ultrasound and Scheimpflug photography. These methods require sophisticated equipment and expertise.
A simple clinical method of quantitatively estimating ACD using smartphone photography (EZ ratio) was developed by Dr Ehud Zamir from the Centre for Eye Research, the University of Melbourne, Australia, and published in 2016.[2]
To calculate the estimated anterior chamber depth, the patient looks at a target in the distance with one eye covered. The examiner takes a digital photograph of the open, examined eye, from the side, perpendicular to the visual axis (a profile photograph).
The following parameters then need to be measured in the photograph, using a personal computer or a smartphone (figures 1,2):
1. The pixel distance between the limbus (the junction between clear cornea and white sclera) and the front of the cornea. This distance is referred to as Z.
2. The pixel distance between the limbus and the centre of the pupil. This distance is referred to as E.
E:Z ratio is the arithmetic ratio between E and Z.
This ratio is linearly correlated with the depth of the anterior chamber with the following equation:
Anterior chamber depth (expressed in millimetres) = -3.3 x EZ ratio + 4.2
This estimate has been shown to be accurate with a 95% confidence interval of +/– 0.33 mm error, when compared to measurements of the anterior chamber depth by Scheimpflug photography.[2]
One peculiar feature of the anterior chamber is dampened immune response to allogenic grafts. This is called anterior chamber associated immune deviation (ACAID), a term introduced in 1981 by Streilein et al.[3][4]
Structures of the eye labeled
This image shows another labeled view of the structures of the eye
Anatomy of the globe of the eye
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Fibrous tunic (outer) |
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Uvea/vascular tunic (middle) |
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Retina (inner) |
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Anatomical regions of the eye |
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Other |
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リンク元 | 「前房」「anterior sac」 |
関連記事 | 「anterior」「bulb」 |
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