WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
PrepTutorEJDIC
- carbonの化学記号
- case[s]
UpToDate Contents
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English Journal
- 5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells.
- Kim KM1, Heo DR1, Lee J1, Park JS1, Baek MG1, Yi JM1, Kim H1, Bang OS2.
- Chemico-biological interactions.Chem Biol Interact.2015 Jan 5;225:32-9. doi: 10.1016/j.cbi.2014.10.033. Epub 2014 Nov 18.
- 5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone (DHTMF) is one of the constituents of Vitex rotundifolia, a medicinal herb that is used for the treatment of various disorders in China and Korea. In this study we evaluated the antitumor and antiangiogeneic activities of DHTMF. DHTMF significantly suppresse
- PMID 25446852
- Sirtuin 6 protects the heart from hypoxic damage.
- Maksin-Matveev A1, Kanfi Y1, Hochhauser E2, Isak A1, Cohen HY1, Shainberg A3.
- Experimental cell research.Exp Cell Res.2015 Jan 1;330(1):81-90. doi: 10.1016/j.yexcr.2014.07.013. Epub 2014 Jul 24.
- Sirtuin 6 (SIRT6) is a protein associated with prolonged life expectancy. We investigated whether life extension is associated with cardioprotection against hypoxia. The proposed study is to develop approaches to reduce hypoxic damage through the use of the sirtuin pathway and to elucidate the mecha
- PMID 25066211
- Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents?
- Dreger P1, Schetelig J2, Andersen N3, Corradini P4, van Gelder M5, Gribben J6, Kimby E7, Michallet M8, Moreno C9, Stilgenbauer S10, Montserrat E11; European Research Initiative on CLL (ERIC) and the European Society for Blood and Marrow Transplantation (EBMT).
- Blood.Blood.2014 Dec 18;124(26):3841-9. doi: 10.1182/blood-2014-07-586826. Epub 2014 Oct 9.
- Allogeneic hematopoietic stem cell transplantation (HSCT) has been considered as the treatment of choice for patients with high-risk chronic lymphocytic leukemia (HR-CLL; ie, refractory to purine analogs, short response [<24 months] to chemoimmunotherapy, and/or presence of del[17p]/TP53 mutation
- PMID 25301705
Japanese Journal
- 初発の表在性低悪性度の膀胱癌においては,増殖状態が再発危険因子である
- Cytosine arabinoside(ara-C)の作用機序,その概念の変遷
Related Links
- キーワード ミトコンドリア、アポトーシス、癌、自己免疫疾患、老人性難聴 歴史とあらまし 1985年、ヒト濾胞性リンパ腫から単離された癌遺伝子としてBcl-2遺伝子が報告された (Ref 1)。1988年にはマウスのB細胞リンパ腫における ...
- 経路の説明: Bcl-2ファミリータンパク質は、ミトコンドリアの透過性を調節することによってアポトーシスを制御します。抗アポトーシスタンパク質のBcl-2とBcl-xLはミトコンドリアの外壁に存在し、シトクロムcの放出を阻害します。
Related Pictures
★リンクテーブル★
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- 英
- proto-oncogene protein c-Bcl-2
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癌原遺伝子産物c-Bcl-2
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- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
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