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1. 男性生殖生理学male reproductive physiology [show details]
…seminiferous tubules and separates the seminiferous tubule compartment from the nests of Leydig cells and other cells in the interstitial compartment. The basal lamina provides the scaffolding of the tubules and …
2. 骨髄造血の制御regulation of myelopoiesis [show details]
…granulocyte precursors in the bone marrow are also compartmentalized into "mitotic" and "storage" compartments. The mitotic cells are actively dividing (myeloblasts, promyelocytes, and myelocytes); while the … comes from studies in mice that carried two null alleles of the GM-CSF gene . These mice had normal basal hematopoiesis, but developed progressive accumulation of surfactant lipids and proteins in the alveolar …
3. 慢性労作性コンパートメント症候群chronic exertional compartment syndrome [show details]
…pressures vary among leg compartments, and more than one compartment may be affected. In a retrospective review involving 226 patients and 153 confirmed cases of CECS, the anterior compartment was elevated in 42 …
4. 四肢の急性コンパートメント症候群の病態生理、分類、原因pathophysiology classification and causes of acute extremity compartment syndrome [show details]
…pressure within a muscular compartment exceeding the perfusion pressure of the tissue has the potential to cause extremity compartment syndrome. Most cases of acute extremity compartment syndrome are associated …
5. 四肢の急性コンパートメント症候群acute compartment syndrome of the extremities [show details]
… limbs are divided into sections, or compartments, formed by strong, unyielding fascial membranes. Compartment syndrome occurs when increased pressure within a compartment compromises the circulation and function …

English Journal

Neuronal Mitophagy: Lessons from a Pathway Linked to Parkinson's Disease.

, C C, O O, O O, .
Neurotoxicity research. 2019 May;().
Neurons are specialized cells with complex and extended architecture and high energy requirements. Energy in the form of adenosine triphosphate, produced essentially by mitochondrial respiration, is necessary to preserve neuronal morphology, maintain resting potential, fire action potentials, and en
PMID 31102068

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland.

Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L.
Scientific reports. 2019 May;9(1)7079.
The VANGL family of planar cell polarity proteins is implicated in breast cancer however its function in mammary gland biology is unknown. Here, we utilized a panel of Vang1 and Vangl2 mouse alleles to examine the requirement of VANGL family members in the murine mammary gland. We show that Vang1CKO
PMID 31068622

Characterization of a New Reconstructed Full Thickness Skin Model, T-Skin™, and its Application for Investigations of Anti-Aging Compounds.

Bataillon M, Lelièvre D, Chapuis A, Thillou F, Autourde JB, Durand S, Boyera N, Rigaudeau AS, Besné I, Pellevoisin C.
International journal of molecular sciences. 2019 May;20(9).
We have characterized a new reconstructed full-thickness skin model, T-Skin™, compared to normal human skin (NHS) and evaluated its use in testing anti-aging compounds. The structure and layer-specific markers were compared with NHS using histological and immunohistological staining. In anti-aging
PMID 31067675

Japanese Journal

Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis

Watanabe Yuto,Kawaue Takumi,Miyata Takaki
Development 145(14), dev162883, 2018-07-17
… Many proliferative epithelia are pseudostratified because of cell cycle-dependent interkinetic nuclear migration (IKNM, basal during G1 and apical during G2). …
NAID 120006536920

Is Vulnerability of the Dentate Gyrus to Aging and Amyloid-β₁₋₄₂ Neurotoxicity Linked with Modified Extracellular Zn²⁺ Dynamics? (New Insights into Neurozinc and Metallothioneins)

Takeda Atsushi,Tamano Haruna
Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 41(7), 995-1000, 2018
… The basal levels of extracellular Zn2+ … concentration reaches picomolar in the extracellular compartment in the dentate gyrus, Zn–Aβ1–42 … is formed in the extracellular compartment and rapidly taken up into dentate granule cells, followed by Aβ1–42-induced cognitive decline that is due to Zn2+ …
NAID 130007387197

Malfunction of spermatogenesis in experimental ischemic mice

YAZAMA Futoshi,SATO Haruki,SONODA Tomoko
家畜繁殖研究會誌 61(5), 399-406, 2015
… Lanthanum had penetrated into the spaces between adjacent Sertoli cells in the adluminal compartment up to the lumen of the seminiferous epithelium in EI testes. … Our results suggest that a change in the junctions between adjacent Sertoli cells on the basal compartment is involved in the BTB disruption in EI testes. …
NAID 130005104113