WordNet

(of genes) producing its characteristic phenotype only when its allele is identical
the 16th letter of the Roman alphabet (同)p
of or relating to an autosome; "autosomal gene"

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1. 小児における常染色体劣性多発性嚢胞腎 autosomal recessive polycystic kidney disease in children
2. 嚢胞性腎疾患の胎児超音波診断 prenatal sonographic diagnosis of cystic renal disease
3. 常染色体優性多発性嚢胞腎の診断およびスクリーニング diagnosis of and screening for autosomal dominant polycystic kidney disease
4. Extracranial carotid artery aneurysm
5. 小児における常染色体優性多発性嚢胞腎 autosomal dominant polycystic kidney disease in children

The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.

Hwang VJ1, Kim J2, Rand A3, Yang C4, Sturdivant S5, Hammock B6, Bell PD7, Guay-Woodford LM4, Weiss RH8.
American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2015 Sep 15;309(6):F492-8. doi: 10.1152/ajprenal.00238.2015. Epub 2015 Jul 8.
Since polycystic kidney disease (PKD) was first noted over 30 years ago to have neoplastic parallels, there has been a resurgent interest in elucidating neoplasia-relevant pathways in PKD. Taking a nontargeted metabolomics approach in the B6(Cg)-Cys1(cpk/)J (cpk) mouse model of recessive PKD, we hav
PMID 26155843

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.

Pavlov TS1, Ilatovskaya DV1, Palygin O1, Levchenko V1, Pochynyuk O2, Staruschenko A3.
Journal of visualized experiments : JoVE.J Vis Exp.2015 Sep 1;(103). doi: 10.3791/53035.
Cyst initiation and expansion during polycystic kidney disease is a complex process characterized by abnormalities in tubular cell proliferation, luminal fluid accumulation and extracellular matrix formation. Activity of ion channels and intracellular calcium signaling are key physiologic parameters
PMID 26381526

Magnetic resonance microscopy of renal and biliary abnormalities in excised tissues from a mouse model of autosomal recessive polycystic kidney disease.

Lee CH1, O'Connor AK2, Yang C2, Tate JM3, Schoeb TR3, Flint JJ1, Blackband SJ4, Guay-Woodford LM5.
Physiological reports.Physiol Rep.2015 Aug;3(8). pii: e12517. doi: 10.14814/phy2.12517.
Polycystic kidney disease (PKD) is transmitted as either an autosomal dominant or recessive trait and is a major cause of renal failure and liver fibrosis. The cpk mouse model of autosomal recessive PKD (ARPKD) has been extensively characterized using standard histopathological techniques after euth
PMID 26320214