WordNet
- increase in price or value; "the news caused a general advance on the stock market" (同)rise
- an amount paid before it is earned (同)cash advance
- rise in rate or price; "The stock market gained 24 points today" (同)gain
- pay in advance; "Can you advance me some money?"
- situated ahead or going before; "an advance party"; "at that time the most advanced outpost was still east of the Rockies" (同)advanced, in advance
- being ahead of time or need; "gave advance warning"; "was beforehand with her report" (同)beforehand
- cause to move forward; "Can you move the car seat forward?" (同)bring forward
- move forward, also in the metaphorical sense; "Time marches on" (同)progress, pass_on, move on, march on, go_on
- move forward; "we have to advance clocks and watches when we travel eastward" (同)set ahead
- bring forward for consideration or acceptance; "advance an argument" (同)throw out
- develop further; "We are advancing technology every day"
- farther along in physical or mental development; "the childs skeletal age was classified as `advanced"; "children in the advanced classes in elementary school read far above grade average"
- ahead of the times; "the advanced teaching methods"; "had advanced views on the subject"; "a forward-looking corporation"; "is British industry innovative enough?" (同)forward-looking, innovative, modern
- far along in time; "a man of advanced age"; "advanced in years"; "a ripe old age"; "the ripe age of 90" (同)ripe
- ahead in development; complex or intricate; "advanced technology"; "a sophisticated electronic control system" (同)sophisticated
- (of societies) highly developed especially in technology or industry; "advanced societies"; "an advanced country technologically"
- at a higher level in training or knowledge or skill; "an advanced degree"; "an advanced text in physics"; "special seminars for small groups of advanced students at the University"
- comparatively late in a course of development; "the illness had reached an advanced stage"; "an advanced state of exhaustion"
- type genus of the family Cancridae (同)genus Cancer
- the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 (同)Cancer the Crab, Crab
- (astrology) a person who is born while the sun is in Cancer (同)Crab
- a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
- any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream (同)malignant neoplastic disease
PrepTutorEJDIC
- …'を'『前進させる』,前に出す / 〈事〉'を'『進める』,促進する / (ある階級・地位などに)〈人〉'を'昇進させる《+『名』〈人〉+『to』+『名』》 / 《『advance』+『名』〈人〉+『名』〈金〉=『advance』+『名』〈金〉+『to』+『名』〈人〉》 〈人〉‘に'〈金〉'を'前払いする,融資する / 〈時間・期日〉'を'早める;〈時計〉‘の'時間を早める / (…に向かって)『前進する』,進む《+『on』(『upon, toward』)+『名』》 / (…に)昇進する《+『to』(『in』)+『名』》 / 〈事が〉進歩する,はかどる / 〈時が〉進む / 〈値段・価値が〉上がる / 〈U〉〈C〉『進むこと』,前進 / 〈U〉(…の)流れ,進行《+『of』+『名』》 / 〈U〉〈C〉(…の)進歩,発達《+『of』+『名』》 / 〈U〉〈C〉(…への)昇進,出世《+『to』+『名』》 / 〈C〉(…の)前払い,前払い金《+『on』+『名』》 / 《複数形で》(人に)言い寄ること,取り入ること《+『to』+『名』》 / 前進している / 前もっての
- 進出した,前進した / 進歩した / 上級の,高等の / (時が)進んだ,進行した
- 〈U〉〈C〉『がん』 / 〈U〉〈C〉害悪 / 《Cancer》(星座の)カニ座
UpToDate Contents
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- 1. 進行非小細胞肺癌の治療の役割 overview of the treatment of advanced non small cell lung cancer
- 2. 末期進行癌における生存期間の推定 survival estimates in advanced terminal cancer
- 3. 癌免疫療法の原則 principles of cancer immunotherapy
- 4. 最新の診療アップデート practice changing updates
- 5. 新たに診断された非転移性乳癌の治療の概要 overview of the treatment of newly diagnosed non metastatic breast cancer
English Journal
- Helicobacter pylori antibody responses and evolution of precancerous gastric lesions in a Chinese population.
- Pan KF1, Formichella L, Zhang L, Zhang Y, Ma JL, Li ZX, Liu C, Wang YM, Goettner G, Ulm K, Classen M, You WC, Gerhard M.Author information 1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing, China.AbstractHelicobacter pylori-specific proteins are involved in gastric carcinogenesis. To investigate the seroprevalence of six H. pylori-specific antibodies in patients with different gastric histology, and the impact of seropositivities on the evolution of precancerous gastric lesions, a follow-up study was conducted in Linqu County, China. The seropositivities for CagA, VacA, GroEL, UreA, HcpC and gGT were assessed by recomLine analysis in 573 H. pylori-positive subjects and correlated with evolution of precancerous gastric lesions. We found that the score of H. pylori recomLine test was significantly increased in subjects with chronic atrophic gastritis (CAG, p < 0.0001) or intestinal metaplasia (IM, p = 0.0125), and CagA was an independent predictor of advanced gastric lesions, adjusted odds ratios (ORs) were 2.54 (95% CI = 1.42-4.55) for IM and 2.38 (95% CI = 1.05-5.37) for dysplasia (DYS). Moreover, seropositivities for CagA and GroEL were identified as independent predictors for progression of gastric lesions in a longitudinal study, and ORs were 2.89 (95% CI = 1.27-6.59) and 2.20 (95% CI = 1.33-3.64), respectively. Furthermore, the risk of progression was more pronounced in subjects with more than three positive antigens (pfor trend = 0.0003). This population-based study revealed that seropositivities for CagA and GroEL might be potential markers to identify patients infected with high-risk H. pylori strains, which are related to the development of GC in a Chinese high-risk population, and recomLine test might serve as a tool for risk stratification.
- International journal of cancer. Journal international du cancer.Int J Cancer.2014 May 1;134(9):2118-25. doi: 10.1002/ijc.28560. Epub 2013 Nov 7.
- Helicobacter pylori-specific proteins are involved in gastric carcinogenesis. To investigate the seroprevalence of six H. pylori-specific antibodies in patients with different gastric histology, and the impact of seropositivities on the evolution of precancerous gastric lesions, a follow-up study wa
- PMID 24155048
- Establishment and identification of induced pluripotent stem cells in liver cancer patients.
- Zhang DM1, Li JJ1, Yan P1, Hu JT2.Author information 1Department of Laparoscopic Surgery, People's Hospital of Zhengzhou, Zhengzhou 450003, China.2Department of Laparoscopic Surgery, People's Hospital of Zhengzhou, Zhengzhou 450003, China. Electronic address: 876893310@qq.com.AbstractOBJECTIVE: To induce pluripotent stem (IPS) cells from fibrocytes that are separated from liver cancer patients.
- Asian Pacific journal of tropical medicine.Asian Pac J Trop Med.2014 Apr;7(4):253-6. doi: 10.1016/S1995-7645(14)60032-8.
- OBJECTIVE: To induce pluripotent stem (IPS) cells from fibrocytes that are separated from liver cancer patients.METHODS: The fibrocytes were reprogrammed to IPS cells by lentiviral vector, stained and identified by immunohistochemistry.RESULTS: The IPS cells were successfully established from fibroc
- PMID 24507670
- Imatinib sensitizes endometrial cancer cells to cisplatin by targeting CD117-positive growth-competent cells.
- Zhang X1, Kyo S2, Nakamura M1, Mizumoto Y1, Maida Y1, Bono Y1, Takakura M1, Fujiwara H1.Author information 1Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan.2Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan. Electronic address: satoruky@med.kanazawa-u.ac.jp.AbstractThe use of molecular target therapy has not been established for endometrial cancer. The present study investigated the potential therapeutic strategy of targeting CD117-positive cancer cells as a novel molecular target therapy. FACS-sorted CD117(+) cells isolated from endometrial cancer cell lines (Ishikawa or MFE280 cells) exhibited higher proliferative capacity in vitro and colony forming activity on soft agar, and decreased sensitivity to cisplatin, compared to CD117(-) cells. Immunohistochemical analyses with surgical specimens of endometrial cancers showed that high CD117 expression was tightly linked to advanced FIGO stages, myometrial invasion and histological grade, and was significantly associated with poor overall survival and relapse-free survival (Kaplan-Meier analysis; p<0.001, log-rank test). The Cox-regression hazard model identified high CD117 expression to be an independent prognostic factor for survival (p<0.05). In vitro assay confirmed that stem cell factor (SCF), a ligand of CD117, was produced specifically in CD117(+) cells of endometrial cancer, and the colony-forming activity were abrogated by adding anti-SCF antibody, indicating an SCF-dependent growth property. Imatinib was confirmed to selectively target CD117(+) cells in vitro, and synergistically enhanced the anti-tumor effect of low dose cisplatin in vivo, which showed only modest effects when used as a single use. These findings suggest that CD117 can be a marker of aggressive behavior of cells as well as an independent prognostic marker in endometrial cancer. Targeting of the SCF/CD117 axis by imatinib sensitized endometrial cancer cells to cisplatin, proposing a novel therapeutic strategy for this tumor type.
- Cancer letters.Cancer Lett.2014 Apr 1;345(1):106-14. doi: 10.1016/j.canlet.2013.11.020. Epub 2013 Dec 11.
- The use of molecular target therapy has not been established for endometrial cancer. The present study investigated the potential therapeutic strategy of targeting CD117-positive cancer cells as a novel molecular target therapy. FACS-sorted CD117(+) cells isolated from endometrial cancer cell lines
- PMID 24333732
Japanese Journal
- 浸潤性膀胱癌に対する術前抗癌化学療法としてのGC療法とMVAC療法の比較
- 川村 憲彦,松下 慎,岡田 宜之,氏家 剛,任 幹夫,辻畑 正雄
- 泌尿器科紀要 59(5), 277-281, 2013-05-00
- … Systemic cisplatin-based chemotherapy regimens are the gold standard in advanced bladder cancer. … We retrospectively evaluated the relative efficacy of the two chemotherapeutic regimens in the management of muscle-invasive bladder cancer on patients who had had radical cystectomy for clinical stage T2-T4, N and, M0 bladder cancer. …
- NAID 120005245088
- Expression of seven-in-absentia homologue 1 and hypoxia-inducible factor 1 alpha: Novel prognostic factors of nasopharyngeal carcinoma
- Kitagawa Noriko,Kondo Satoru,Wakisaka Naohiro,Zen Yoh,Nakanishi Yosuke,Tsuji Akira,Endo Kazuhira,Murono Shigeyuki,Yoshizaki Tomokazu
- Cancer
- … Nasopharyngeal carcinoma (NPC) is an EBV-associated cancer. … We analysed Siah1 expression as well as LMP1 and HIF1α expression by immuno-histochemical staining in 74 NPC biopsy specimens and found that the expression of Siah1 was significantly correlated with advanced tumour status and stage. …
- NAID 120005253837
- Paclitaxel単剤による術前化学療法で臨床的完全奏効を認めたstageIV進行乳癌の１例
- 吉田 咲耶子,原田 道彦,春日 好雄,家里 明日美,大場 崇旦
- 信州医学雑誌 61(2), 75-82, 2013-04-10
- NAID 120005248177
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★リンクテーブル★
| リンク元 | 「進行癌」「進行がん」 |
| 関連記事 | 「advance」「advanced」「cancer」 |
「進行癌」
- 英
- advanced cancer
- 同
- 進展癌、進行がん
- 関
- 癌
「進行がん」
- 英
- advanced cancer
- 関
- 進行癌
「advance」
- n.
- v.
- 進行する、進歩する、前進する、進む
「advanced」
- adj.
- 高度な、先端的な、進行型の、後生的な
「cancer」