WordNet

a drug combination found in some over-the-counter headache remedies (aspirin and phenacetin and caffeine)
(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
a pass between mountain peaks (同)gap
informal term for information; "give me the gen on your new line of computers"

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1. 家族性腺腫性ポリポーシスの臨床症状および診断 clinical manifestations and diagnosis of familial adenomatous polyposis
2. 家族性腺腫性ポリポーシス：患者および家族のスクリーニングおよびマネージメント familial adenomatous polyposis screening and management of patients and families
3. 大腸癌の分子遺伝学 molecular genetics of colorectal cancer
4. 大腸癌：疫学、危険因子、および防御因子 colorectal cancer epidemiology risk factors and protective factors
5. 髄芽腫の組織病理および分子学的病因 histopathology and molecular pathogenesis of medulloblastoma

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.

Tanaka N1,2, Mashima T1, Mizutani A1, Sato A1,3, Aoyama A3,4, Gong B3,4, Yoshida H1, Muramatsu Y1, Nakata K1,5, Matsuura M6, Katayama R4, Nagayama S7, Fujita N3,4,5, Sugimoto Y2, Seimiya H8,3,5.
Molecular cancer therapeutics.Mol Cancer Ther.2017 Apr;16(4):752-762. doi: 10.1158/1535-7163.MCT-16-0578. Epub 2017 Feb 8.
PMID 28179481

Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.

Thean LF1, Wong YH1, Lo M1, Loi C1, Chew MH1, Tang CL1, Cheah PY1,2,3.
PloS one.PLoS One.2017 Mar 17;12(3):e0173772. doi: 10.1371/journal.pone.0173772. eCollection 2017.
PMID 28306719

Wachsmannova L, Mego M, Stevurkova V, Zajac V, Ciernikova S.
Neoplasma.Neoplasma.2017 Mar 3;64(3). doi: 10.4149/neo_2017_303. [Epub ahead of print]
Colorectal cancer is the 4th most common cause of cancer related deaths worldwide and new possibilities in accurate diagnosis and targeted treatment are highly required. Mutations in adenomatous polyposis coli (APC) gene play a pivotal role in adenoma-carcinoma pathway of colorectal tumorigenesis. T
PMID 28253712

Successful outcome after laparoscopic surgery for sporadic colonic desmoid tumor with β-catenin mutation: a case report.

Gunji Shutaro,Kawada Kenji,Kawada Mayumi,Hasegawa Suguru,Sakai Yoshiharu
Journal of medical case reports 7(1), 2013-04-10
… They are rare neoplastic tumors that may occur sporadically or in association with familial adenomatous polyposis caused by a germline mutation in the adenomatous polyposis coli gene. … She had no history of familial adenomatous polyposis, abdominal surgery, trauma or pregnancy. …
NAID 120005323030

Cardamonin Suppresses the Proliferation of Colon Cancer Cells by Promoting β-Catenin Degradation

Park Seoyoung,Gwak Jungsug,Han Seung Jin [他],Oh Sangtaek
Biological and Pharmaceutical Bulletin 36(6), 1040-1044, 2013
… Here we show that cardamonin, a chalcone isolated from Aplinia katsumadai <span style="font-variant: small-caps;">Hayata</span>, inhibited CRT in SW480 colon cancer cells that carry inactivating mutation in the adenomatous polyposis coli (APC) gene. …
NAID 130003361462

Birt-Hogg-Dubé Syndrome and Familial Adenomatous Polyposis: An Association or a Coincidence?

Kashiwada Takeru,Shimizu Hidefumi,Tamura Kazuo,Seyama Kuniaki,Horie Yoshimasa,Mizoo Akira
Internal Medicine 51(13), 1789-1792, 2012
… The 60-year-old woman was diagnosed at 28 years of age with colon carcinoma and familial adenomatous polyposis (FAP). … We confirmed the presence of germline mutations in both her folliculin (FLCN) and adenomatous polyposis coli (APC) genes. …
NAID 130002062197