急性網膜壊死 ARN
WordNet
- of critical importance and consequence; "an acute (or critical) lack of research funds"
- having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
- extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
- having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
- of an angle; less than 90 degrees
- in or relating to the retina of the eye; "retinal cells"
- the localized death of living cells (as from infection or the interruption of blood supply) (同)mortification, gangrene, sphacelus
- the innermost light-sensitive membrane covering the back wall of the eyeball; it is continuous with the optic nerve
PrepTutorEJDIC
- (先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
- 壊疽(えそ)
- (目の)網膜
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/03/25 20:31:31」(JST)
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Acute retinal necrosis |
Classification and external resources |
eMedicine |
oph/377 |
MeSH |
D015882 |
Acute retinal necrosis is a type of retinitis which can be associated with viral infections.
It was first characterized in 1971.[1][2]
One study indicated an incidence of 1 per 1.6 to 2.0 million.[3]
Contents
- 1 Causes
- 2 Treatment
- 3 See also
- 4 References
- 5 External links
Causes[edit]
The exact causes are not known, but varicella zoster virus is frequently implicated,[4] and other herpesviruses can be involved.[5]
Treatment[edit]
Treatments that have been used include foscarnet,[6] valacyclovir and famciclovir.[7]
See also[edit]
- Cytomegalovirus retinitis
- Progressive outer retinal necrosis
References[edit]
- ^ "eMedicine - Acute Retinal Necrosis : Article by Andrew A Dahl, MD". Archived from the original on 16 February 2008. Retrieved 2008-02-05.
- ^ Urayama A, Yamada N, Sasaki T: Unilateral acute uveitis with retinal periarteritis and detachment. Jpn J Clin Ophthalmol 1971; 25: 607.
- ^ Muthiah MN, Michaelides M, Child CS, Mitchell SM (2007). "Acute retinal necrosis: a national population‐based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK". Br J Ophthalmol 91 (11): 1452–5. doi:10.1136/bjo.2007.114884. PMC 2095441. PMID 17504853.
- ^ Lau CH, Missotten T, Salzmann J, Lightman SL (2007). "Acute retinal necrosis features, management, and outcomes". Ophthalmology 114 (4): 756–62. doi:10.1016/j.ophtha.2006.08.037. PMID 17184841.
- ^ Kezuka T, Atherton SS (2007). "Acute retinal necrosis". Chem Immunol Allergy. Chemical Immunology and Allergy 92: 244–53. doi:10.1159/000099275. ISBN 3-8055-8187-4. PMID 17264500.
- ^ King J, Chung M, DiLoreto DA (2007). "A 9 year-old girl with herpes simplex virus type 2 acute retinal necrosis treated with intravitreal foscarnet". Ocul. Immunol. Inflamm. 15 (5): 395–8. doi:10.1080/09273940701486431. PMID 17972224.
- ^ Emerson GG, Smith JR, Wilson DJ, Rosenbaum JT, Flaxel CJ (2006). "Primary treatment of acute retinal necrosis with oral antiviral therapy". Ophthalmology 113 (12): 2259–61. doi:10.1016/j.ophtha.2006.05.063. PMID 16996614.
External links[edit]
- http://www.iceh.org.uk/files/tsno8/text/18.htm
- http://www.eyepathologist.org/disease.asp?IDNUM=301330
UpToDate Contents
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English Journal
- Acute retinal necrosis associated optic neuropathy.
- Witmer MT, Pavan PR, Fouraker BD, Levy-Clarke GA.SourceDepartment of Ophthalmology, College of Medicine, University of South Florida, Tampa, Florida, USA St. Luke's Cataract and Laser Institute, Tarpon Springs, Florida, USA.
- Acta ophthalmologica.Acta Ophthalmol.2011 Nov;89(7):599-607. doi: 10.1111/j.1755-3768.2010.01911.x. Epub 2010 Jul 20.
- Acute retinal necrosis (ARN) syndrome is characterized by severe intraocular inflammation, occlusive vasculopathy and peripheral retinal necrosis. Vision threatening complications of this syndrome include retinal detachment, macular oedema and ischaemia and optic neuropathy. Optic nerve involvement
- PMID 20645925
- Ocular Behçet disease: current therapeutic approaches.
- Evereklioglu C.SourceDivision of Uvea-Behçet Unit, Department of Ophthalmology, Erciyes University Medical Faculty, Kayseri, Turkey.
- Current opinion in ophthalmology.Curr Opin Ophthalmol.2011 Nov;22(6):508-16.
- PURPOSE OF REVIEW: To alert physician to timely recognition and current treatment of recurrent hypopyon iridocyclitis or panuveitis in ocular Behçet disease (OBD).RECENT FINDINGS: Interferon-α, rituximab, intravitreal triamcinolone, and biological response modifiers by tumor necrosis factor inhibi
- PMID 21897239
Japanese Journal
- 臨床報告 新生児ヘルペス脳炎を伴った未熟児に生じた急性網膜壊死
- 発症から24年後に僚眼に再発した急性網膜壊死の1例 (特集 第67回日本臨床眼科学会講演集(5))
- 急性網膜壊死における原因ウイルスと臨床経過 (特集 第67回日本臨床眼科学会講演集(5))
Related Pictures
![Acute Retinal Necrosis - Retina Image Bank](https://1mg.info/0/j/i/1862.jpg)
![Retinal necrosis syndrome, acute; Acute Retinal Necrosis](https://1mg.info/0/j/i/1863.jpg)
![Retinal necrosis syndrome, acute; Acute Retinal Necrosis](https://1mg.info/0/j/i/1864.jpg)
![Acute retinal necrosis - Retina Image Bank](https://1mg.info/0/j/i/1865.jpg)
![Challenges in the management of acute retinal necrosis | Ophthalmology Magazine](https://1mg.info/0/j/i/1866.jpg)
★リンクテーブル★
[★]
- 英
- acute retinal necrosis ARN
- 同
- 桐沢型ぶどう膜炎、急性網膜壊死症候群 acute retinal necrosis syndrome
- 関
- 眼内炎
概念
- 急激に発症する激しいぶどう膜網膜炎を特徴とする疾患(3)。急性汎ぶどう膜炎。
- 水痘帯状疱疹ウイルスあるいは単純ヘルペスウイルスの眼内局所感染によって発症する急性後部ぶどう膜炎で、周辺網膜の壊死を伴う。
- 1971年浦山晃らが桐沢型ぶどう膜炎として初めて報告(3)
病因
疫学
病変形成&病理
病態
病理
- 硝子体混濁 + 眼底の網膜に黄白色の滲出斑が出現、癒合 → 網膜の壊死 → (1-2ヶ月後)網膜の萎縮・変性 → 多数の網膜裂孔 → 網膜剥離 (3)
- 静脈に沿った帯状の出血(3)
症状
診断
- 眼底所見:眼底網膜に黄白色の滲出斑。静脈に沿った帯状の出血
- 前房水:ヘルペスウイルスDNAのからの検出
- 前房水 or 硝子体液:ヘルペスウイルス抗体価
検査
蛍光眼底造影
治療
薬物療法
- 抗ウイルス薬(アシクロビル)
- ステロイドの全身投与
手術療法
予後
参考
(3) 現代の眼科学 第10版第1刷 金原出版株式会社 ISBN 9784307351355
http://emedicine.medscape.com/article/1223047-overview
-acute retinal necrosis
- 同
- ARN
[★]
急性網膜壊死 acute retinal necrosis
[★]
- 関
- acute retinal necrosis
[★]
- (疾患)急性の、急性型の、急性的な。(形状が)鋭い、鋭角の。(感覚、才知などが)鋭い。明敏な、鋭い眼識のある。
- 関
- acutely、quick、sharp
[★]
- 関
- 11-cis-retinal、retina、retinae、retinaldehyde, retinol