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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/05/23 09:21:33」(JST)

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1. 成人の精神刺激薬使用障害への薬物療法pharmacotherapy for stimulant use disorders in adults [show details]
…neurotransmission. Vigabatrin and topiramate are GABAergic medications that have been tested in cocaine use disorder; clinical trials have found mixed results on the efficacy of topiramate in preventing relapse …
2. 小児の双極性障害：治療法の選択に関する概要pediatric bipolar disorder overview of choosing treatment [show details]
…with mania found that improvement was comparable for both groups . Topiramate – In a four-week randomized trial that compared topiramate (mean daily dose 278 mg) with placebo in 56 children and adolescents …
3. 抗痙攣薬：作用機序、薬理学および副作用antiseizure drugs mechanism of action pharmacology and adverse effects [show details]
…frequency of somnolence when TPM was used as add-on therapy in patients with epilepsy , monotherapy with TPM 200 mg/day does not appear to impair daytime vigilance in adult patients . TPM has been associated with …
4. 成人における片頭痛の予防的治療preventive treatment of migraine in adults [show details]
…using topiramate during pregnancy, since topiramate is associated with an increased risk of facial clefts and may increase the risk of low birth weight. Data from one trial suggest that topiramate has …
5. 小児における片頭痛の予防的治療preventive treatment of migraine in children [show details]
…randomized controlled trials regarding the efficacy of topiramate for migraine prevention in children: A 2013 meta-analysis concluded that topiramate is more effective than placebo for episodic migraine …

English Journal

High Incidence of Renal Stones in Severely Disabled Children with Epilepsy Treated with Topiramate.

Ishikawa N, Tani H, Kobayashi Y, Kato A, Kobayashi M.
Neuropediatrics. 2019 Jun;50(3)160-163.
This study was aimed to assess the accurate incidence of renal stones in severely disabled children treated with topiramate (TPM). We reviewed the medical records of severely disabled children with epilepsy under 15 years old who underwent radiological examinations to investigate urinary stone
PMID 30939600

Colloidal organosilica spheres for three-dimensional confocal microscopy.

Liu Y, Yanagishima T, Curran A, Edmond KV, Sacanna S, Dullens RPA.
Langmuir : the ACS journal of surfaces and colloids. 2019 May;().
We describe the synthesis and application of 3-(trimethoxysilyl)propyl methacrylate (TPM) particles as a colloidal model system for three-dimensional (3D) confocal scanning laser microscopy. The effect of the initial TPM concentration on the growth and polydispersity of the particles and a recently
PMID 31095907

Pinellia Total Alkaloids Modulate the GABAergic System in Hippocampal Formation on Pilocarpine-Induced Epileptic Rats.

Deng CX, Wu ZB, Chen Y, Yu ZM.
Chinese journal of integrative medicine. 2019 May;().
To investigate the neuromodulatory effect of pinellia total alkaloids (PTA) on the gamma-aminobutyric acidergic (GABAergic) system in epileptic rats, and preliminarily evaluate the anti-epileptic effect of PTA. Ninety-one male Sprague-Dawley rats were randomized to a control group (n=17) or an epile
PMID 31093879