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Kudo K, Ichihara E, Hisamoto A, Hotta K, Miyahara N, Tanimoto Y, Akagi S, Kato K, Tanimoto M, Kiura K.SourceDepartment of Allergy and Respiratory Medicine, Okayama University Hospital, Japan. kudoken19800411@yahoo.co.jp
Internal medicine (Tokyo, Japan).Intern Med.2013;52(1):97-100. Epub 2013 Jan 1.
A 32-year-old male with CATCH22 syndrome presented with a high fever and productive cough after taking drugs for acute bronchitis, including (L)-carbocisteine. Chest radiography revealed ground-glass opacities in the bilateral lung fields. He had a history of similar pneumonia. Under the assumption
PMID 23291681

l-carbocisteine inhibits respiratory syncytial virus infection in human tracheal epithelial cells.

Asada M, Yoshida M, Hatachi Y, Sasaki T, Yasuda H, Deng X, Nishimura H, Kubo H, Nagatomi R, Yamaya M.SourceDepartment of Infectious Disease, Sendai City Hospital, Sendai, Japan.
Respiratory physiology & neurobiology.Respir Physiol Neurobiol.2012 Jan 15;180(1):112-8. doi: 10.1016/j.resp.2011.10.017. Epub 2011 Nov 7.
To examine the effects of l-carbocisteine on airway infection with respiratory syncytial (RS) virus, human tracheal epithelial cells were pretreated with l-carbocisteine and infected with RS virus. Viral titer, virus RNA, and pro-inflammatory cytokine secretion, including interleukin (IL)-1 and IL-6
PMID 22080978

[Expression and role of sugar chains on airway mucus during the exacerbation of airway inflammation].

Ishibashi Y, Inouye Y, Taniguchi A.SourceDiscovery Research Laboratories, Kyorin Pharmaceutical Co., Ltd., Tochigi, Japan. yuuji.ishibashi@mb.kyorin-pharm.co.jp
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.Yakugaku Zasshi.2012;132(6):699-704.
Human bronchial mucins, such as MUC5AC, have traditionally been defined as a family of high-molecular weight glycoproteins. Changes in the contents of sugar chains on MUC5AC are among the fundamental features in inflammatory respiratory disease. The changes have been shown to lead to unfavorable alt
PMID 22687728

是枝快泉,田上あさ子,隈元朋洋,窪田幸司,萩原陽子,太良哲彦,野間聖,川畠寿史,末次隆行,松山航,水野圭子,川畑政治,東元一晃,納光弘,有村公良
日本呼吸器学会雑誌 = The journal of the Japanese Respiratory Society 45(8), 609-614, 2007-08-10
NAID 10019968313