English Journal

Nosocomial spread of meticillin-resistant Staphylococcus aureus with β-lactam-inducible arbekacin resistance.

Harada Y1, Chong Y, Shimono N, Miyake N, Uchida Y, Kadowaki M, Akashi K, Shimoda S.
Journal of medical microbiology.J Med Microbiol.2014 May;63(Pt 5):710-4. doi: 10.1099/jmm.0.065276-0. Epub 2014 Feb 3.
A meticillin-resistant Staphylococcus aureus (MRSA) strain with additional β-lactam-inducible aminoglycoside resistance was previously reported by a group at the Kitasato University in Japan. In addition to gentamicin, the 'Kitasato strain' was resistant to arbekacin (ABK), which is primarily used
PMID 24493159

[Safety and pharmacokinetics of 400 and 600 mg arbekacin sulfate to healthy male volunteers].

Sunakawa K1, Hori S.
The Japanese journal of antibiotics.Jpn J Antibiot.2013 Apr;66(2):97-109.
We assessed the safety and pharmacokinetics of arbekacin sulfate (ABK, brand name: Habekacin injection) in single and 7-day multiple administration of ABK 400 and 600 mg as potency to healthy male volunteers. In the single administration of ABK 400 and 600 mg (over 30 min, drip infusion), C(max) val
PMID 23951728

Rapid quantification of the aminoglycoside arbekacin in serum using high performance liquid chromatography-tandem mass spectrometry.

Breaud AR1, Henemyre-Harris CL, Schools S, Emezienna N, Clarke W.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2013 Mar 15;418:102-6. doi: 10.1016/j.cca.2013.01.004. Epub 2013 Jan 17.
BACKGROUND: This project entails the development and validation of a method for quantification of the aminoglycoside antibiotic arbekacin in serum using liquid chromatography tandem mass spectrometry (LC-MS/MS) for therapeutic drug monitoring in future clinical trials.METHODS: Following a protein pr
PMID 23333924

Japanese Journal

硫酸アルベカシンにおける投与設計に際しての留意点 : Sawchuk-Zaske法とBayesian法を用いた場合の比較

梶田貴司,上田睦明,巽久美代,西川豊,橋本亜衣子,中塚英太郎,山本育由
医療薬学 30(12), 777-782, 2004-12-10
… We also compared measured values with values predicted based on patients' pharmacokinetic parameters (population means) using the initial dosage design function of TDM software for Habekacin^[○!R] (Research Committee for Anti-MRSA Drugs). …
NAID 110001171450

硫酸アルベカシンにおける投与設計に際しての留意点―Ｓａｗｃｈｕｋ‐Ｚａｓｋｅ法とＢａｙｅｓｉａｎ法を用いた場合の比較:-Sawchuk-Zaske法とBayesian法を用いた場合の比較

梶田貴司,上田睦明,巽久美代,西川豊,橋本亜衣子,中塚英太郎,山本育由
医療薬学 30(12), 777-782, 2004
… We also compared measured values with values predicted based on patients' pharmacokinetic parameters (population means) using the initial dosage design function of TDM software for Habekacin ® (Research Committee for Anti-MRSA Drugs). …
NAID 130004346579

MRSA感染による副鼻腔炎に対するABKを用いたネブライザー療法

小川晃弘,山根辰生,岸本朋之,曽田益弘
耳鼻咽喉科展望 43(Supplement1), 5-10, 2000
MRSAによる副鼻腔炎も治療に困難を伴うことが多い。このたび姫路聖マリア病院においてMRSA感染による副鼻腔炎5症例に対して, 1回8.3mgのABKをネブライザーを用いて直接局所に作用させて除菌を試みた。ネブライザーは外来で週1回の施行を原則としたが, 副作用を発現した症例はなかった。<BR>治療後2回連続して中鼻道の細菌検査でMRSAが検出されない状態で, 除菌を得られたと判断した …
NAID 130003975205

Related Pictures

阿贝卡星注射剂 habekacin 418, gentamycin, hygromycin, habekacin habekacin amp arbekacin sulfate 13139-17-8,C12H11NO5,249.2252,N Benzyloxycarbonyl chloride; Benzyl Click image to enlarge