HLA-B8 antigen

• HLA-B8抗原

関

HLA-B8

WordNet

1. the 2nd letter of the Roman alphabet (同)b
2. the blood group whose red cells carry the B antigen (同)type_B, group B
3. the 8th letter of the Roman alphabet (同)h
4. any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

PrepTutorEJDIC

1. hydrogenの化学記号
2. 鉛筆の硬度 / 《俗》heroin
3. 抗原(生物の体内にはいって免疫体を作る物質)

UpToDate Contents

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• 1. 線状IgA水疱性皮膚症 linear iga bullous dermatosis
• 2. IgA nephropathy: Recurrence after transplantation
• 3. Autoimmune hepatitis: Pathogenesis
• 4. 自己免疫性副腎不全の病因 pathogenesis of autoimmune adrenal insufficiency
• 5. 補体系の遺伝性疾患 inherited disorders of the complement system

English Journal

• Human leukocyte antigen type and posttransplant lymphoproliferative disorder.

• Lustberg ME1, Pelletier RP, Porcu P, Martin SI, Quinion CD, Geyer SM, Caligiuri MA, Baiocchi RA.
• Transplantation.Transplantation.2015 Jun;99(6):1220-5. doi: 10.1097/TP.0000000000000487.
• BACKGROUND: Posttransplant lymphoproliferative disorder (PTLD) is an infrequent but serious complication of solid organ transplantation. Early detection and initiation of therapy may improve outcomes. The purpose of this study was to identify human leukocyte antigen (HLA) type as risk and prognostic
• PMID 25427163
• PMID 25655558

• The autoimmune spectrum of myasthenia gravis: a Swedish population-based study.

• Fang F1, Sveinsson O, Thormar G, Granqvist M, Askling J, Lundberg IE, Ye W, Hammarström L, Pirskanen R, Piehl F.
• Journal of internal medicine.J Intern Med.2015 May;277(5):594-604. doi: 10.1111/joim.12310. Epub 2014 Nov 13.
• OBJECTIVES: To determine the prevalence of myasthenia gravis (MG) and the rate of concurrent autoimmune diseases in patients with MG.DESIGN AND SETTING: Using the Swedish health and population registers, during the period 2005-2010, we conducted a nested case-control study of patients with MG (n = 2
• PMID 25251578

Japanese Journal

• The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen

• WARREN EH
• J Immunol. 164, 2807-2814, 2000
• NAID 80011598170

• Pathogenesis and Treatment of Myasthenia Gravis

• ARIMORI Shigeru
• Tokai journal of experimental and clinical medicine 11(Supplement), 159-169, 1986-10-17
• … HLA antigen frequencies in 49 patients with MG were studied to investigate a genetic background. … Although the association of HLA-B8, DR3, DRw52 haplotype with Caucasian MG has been reported, Japanese MG seems to be associated with a different haplotype, HLA-B39, Cw7, DRw8. …
• NAID 110004691220

• HLA-Bw52-DHO ハプロタイプの免疫生物学的機能

• 河野 陽一
• アレルギー 27(12), 933-942, 946, 1978-12-30
• … にして HLA システムの免疫遺伝学的意義を明らかにすることを目的とした.日本人一般集団は, 破傷風トキソイドに対する免疫応答群と非応答群とに分けられ, さらに非応答群と HLA-Bw52-DHO ハプロタイプがヘテロで強い相関を示すことから, これと連鎖不平衡にある免疫抑制遺伝子の存在が初めて示唆された.日本人集団では, 臓器特異的自己免疫性疾患であるバセドウ病が HLA-Bw52-DHO …
• NAID 110002411170

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★リンクテーブル★

関連記事	「B」「HL」「H」「HLA」

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「HL」

　　[★]

• ホジキンリンパ腫 Hodgkin's lymphoma
• 高脂質血症 hyperlipidemia
• high lateral branch

「H」

　　[★]

• 食道裂孔
• ヒスチジン
• 水素

　 　 　

「HLA」

　　[★] ヒト白血球抗原 human leukocyte antigen