WordNet
- direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
- a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
- a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
- (often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
- a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
- a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
- official routes of communication; "you have to go through channels"
PrepTutorEJDIC
- 〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
- アメリカ兵[Government Issue(政府支給)の略]・官給の,軍隊式の
UpToDate Contents
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- 1. 腎集合管ナトリウムチャンネルの遺伝的障害：リドル症候群および偽性低アルドステロン
症1型 genetic disorders of the collecting tubule sodium channel liddles syndrome and pseudohypoaldosteronism type 1 - 2. 赤血球水分量の制御 control of red blood cell hydration
- 3. 幼児の持続性高インスリン血症性低血糖症の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of persistent hyperinsulinemic hypoglycemia of infancy
- 4. カルシウム拮抗剤の主な副作用および安全性 major side effects and safety of calcium channel blockers
- 5. 安定狭心症のマネージメントにおけるカルシウム拮抗剤 calcium channel blockers in the management of stable angina pectoris
English Journal
- Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model.
- Kanbara T1, Nakamura A1, Shibasaki M2, Mori T2, Suzuki T2, Sakaguchi G3, Kanemasa T4.
- Neuroscience letters.Neurosci Lett.2014 Sep 19;580:119-24. doi: 10.1016/j.neulet.2014.08.005. Epub 2014 Aug 12.
- It has begun to be understood that μ-opioid receptor (MOR) produces ligand-biased agonism, which contributes to differential physiological functions of MOR agonists. We previously demonstrated that in oxaliplatin-induced neuropathy in rats, morphine and oxycodone exhibited antinociceptive effects w
- PMID 25128218
- Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.
- Mattis J1, Brill J2, Evans S3, Lerner TN4, Davidson TJ4, Hyun M4, Ramakrishnan C4, Deisseroth K5, Huguenard JR6.
- The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2014 Aug 27;34(35):11769-80. doi: 10.1523/JNEUROSCI.5188-13.2014.
- Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hippocampus onto septal cells, and are therefore likely to also play an important role in the circuit;
- PMID 25164672
- Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.
- Wydeven N1, Marron Fernandez de Velasco E1, Du Y2, Benneyworth MA3, Hearing MC3, Fischer RA3, Thomas MJ3, Weaver CD4, Wickman K5.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Jul 22;111(29):10755-60. doi: 10.1073/pnas.1405190111. Epub 2014 Jul 7.
- ML297 was recently identified as a potent and selective small molecule agonist of G-protein-gated inwardly rectifying K(+) (GIRK/Kir3) channels. Here, we show ML297 selectively activates recombinant neuronal GIRK channels containing the GIRK1 subunit in a manner that requires phosphatidylinositol-4,
- PMID 25002517
Japanese Journal
- 2SBP-05 G タンパク質共役型内向き整流性カリウムイオンチャネル1(GIRK1)のG タンパク質による機能調節の構造基盤(シグナル伝達機構における構造細胞生物学的新展開,新学術領域研究「細胞シグナリング複合体によるシグナル検知・伝達・応答の構造的基礎」共催,シンポジウム,第52回日本生物物理学会年会(2014年度))
- 大澤 匡範,間瀬 瑤子,横川 真梨子,竹内 恒,嶋田 一夫
- 生物物理 54(SUPPLEMENT_1-2), S131, 2014-08-20
- NAID 110009932171
- Association Between KCNJ6 (GIRK2) Gene Polymorphism rs2835859 and Post-operative Analgesia, Pain Sensitivity, and Nicotine Dependence
- Nishizawa Daisuke,Fukuda Ken-ichi,Kasai Shinya [他],Ogai Yasukazu,Hasegawa Junko,Sato Naomi,Yamada Hidetaka,Tanioka Fumihiko,Sugimura Haruhiko,Hayashida Masakazu,Ikeda Kazutaka
- Journal of Pharmacological Sciences 126(3), 253-263, 2014
- … G-protein–activated inwardly rectifying potassium (GIRK) channels are expressed in many tissues and activated by several Gi/o protein–coupled receptors, such as opioid and dopamine receptors, and thus are known to be involved in the modulation of opioid-induced analgesia, pain, and reward. …
- NAID 130004700283
- 日本のアルコール依存症の入院患者における再飲酒リスクにGIRKチャネル阻害剤が与える影響
- 菅谷 渚,大谷 保和,垣渕 洋一,妹尾 栄一,池田 和隆
- 日本神経精神薬理学雑誌 = Japanese journal of psychopharmacology 33(2), 57-58, 2013-04-25
- NAID 10031169390
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Related Pictures
★リンクテーブル★
| リンク元 | 「Gタンパク質共役型内向き整流性カリウムチャネル」「GIRKチャネル」「G protein-coupled inwardly-rectifying potassium channel」 |
| 関連記事 | 「GI」「channel」 |
「Gタンパク質共役型内向き整流性カリウムチャネル」
「GIRKチャネル」
「G protein-coupled inwardly-rectifying potassium channel」
「GI」
- adj.
- 胃腸の、消化管の、消化器系の、胃腸管系の
- 関
- alimentary canal、alimentary system、alimentary tract、digestive system、digestive tract、gastrointestinal、gastrointestinal system、gastrointestinal tract、GI tract、intestinal
「channel」
- n.
- 川床、川底。水路、河道
- 海峡
- 水管、導管
- 溝
- 経路、ルート。道筋、方向