WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
- the 7th letter of the Roman alphabet (同)g
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- 高山,高峰
UpToDate Contents
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English Journal
- G(alpha)12/13 induction of CYR61 in association with arteriosclerotic intimal hyperplasia: effect of sphingosine-1-phosphate.
- Kim YM1, Lim SC, Han CY, Kay HY, Cho IJ, Ki SH, Lee MY, Kwon HM, Lee CH, Kim SG.
- Arteriosclerosis, thrombosis, and vascular biology.Arterioscler Thromb Vasc Biol.2011 Apr;31(4):861-9. doi: 10.1161/ATVBAHA.110.218552. Epub 2011 Jan 6.
- OBJECTIVE: Gα(12/13) play a role in oncogenic transformation and tumor growth. Cysteine-rich protein 61 (CYR61) is a growth-factor-inducible angiogenic factor. In view of potential overlapping functions between Gα(12/13) and CYR61, this study investigated the role of these G proteins in CYR61 indu
- PMID 21212405
- A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
- Goupil E1, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA.
- The Journal of biological chemistry.J Biol Chem.2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15.
- The prostaglandin F2alpha (PGF2alpha) receptor (FP) is a key regulator of parturition and a target for pharmacological management of preterm labor. However, an incomplete understanding of signaling pathways regulating myometrial contraction hinders the development of improved therapeutics. Here we u
- PMID 20551320
- G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation.
- Yang YM1, Lee S, Nam CW, Ha JH, Jayaraman M, Dhanasekaran DN, Lee CH, Kwak MK, Kim SG.
- Carcinogenesis.Carcinogenesis.2010 Jul;31(7):1230-7. doi: 10.1093/carcin/bgq097. Epub 2010 May 17.
- Bortezomib is a proteasome inhibitor approved for anticancer therapy. However, variable sensitivity of tumor cells exists in this therapy probably due to differences in the expression of proteasome subunits. G(alpha)(12/13) serves modulators or signal transducers in diverse pathways. This study inve
- PMID 20478922
Japanese Journal
- Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
- G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
- Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product
Related Links
- Buy G alpha 12 antibody / G alpha 12 antibodies from Santa Cruz Biotech. Monoclonal and polyclonal antibodies are available to most protein immunogen targets. ... HOVERcruz ,を紹介します。G alpha 12 Antibodiesを迅速に識別 ...
- 1. J Biol Chem. 2005 May 6;280(18):18434-41. Epub 2005 Mar 1. G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor ...
Related Pictures
★リンクテーブル★
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- 英
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- Gα12サブユニット
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- 英
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- Gα12
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α、アルファ
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- alfa
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- 同
- ガドリニウム造影MRI
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グラム
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- gram