Gα11サブユニット、Gα11

WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
the 7th letter of the Roman alphabet (同)g
any high mountain

PrepTutorEJDIC

アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
高山,高峰

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1. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
2. α-1アンチトリプシン欠乏の治療 treatment of alpha 1 antitrypsin deficiency
3. αサラセミアの病態生理 pathophysiology of alpha thalassemia
4. ステロイド5 -α-レダクターゼ2欠乏症 steroid 5 alpha reductase 2 deficiency
5. 複合免疫不全 combined immunodeficiencies

English Journal

Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes.

Hoyer DP1, Grönke S, Frank KF, Addicks K, Wettschureck N, Offermanns S, Erdmann E, Reuter H.
Molecular and cellular biochemistry.Mol Cell Biochem.2010 Aug;341(1-2):235-44. doi: 10.1007/s11010-010-0454-1. Epub 2010 Apr 7.
Neurohumoral stimulation of Gq-coupled receptors has been proposed as a central mechanism in the pathogenesis of diabetic heart disease. The resulting contractile dysfunction is closely related to abnormal intracellular Ca(2+) handling with functional defects of the sarcoplasmic reticulum (SR). The
PMID 20372981

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology.

McCoy KL1, Traynelis SF, Hepler JR.
Molecular pharmacology.Mol Pharmacol.2010 Jun;77(6):1005-15. doi: 10.1124/mol.109.062018. Epub 2010 Mar 9.
The protease-activated receptors (PAR1 and PAR2) are unusual G protein-coupled receptors that are activated by distinct serine proteases and are coexpressed in many different cell types. Limited recent evidence suggests these closely related receptors regulate different physiological outputs in the
PMID 20215560

Role of vasoactive peptides in high glucose-induced increased expression of Gαq/11 proteins and associated signaling in vascular smooth muscle cells.

Descorbeth M1, Anand-Srivastava MB.
Canadian journal of physiology and pharmacology.Can J Physiol Pharmacol.2010 Mar;88(3):331-40. doi: 10.1139/Y09-132.
We have recently shown that A10 vascular smooth muscle cells (VSMCs) exposed to high glucose exhibited enhanced expression of G(alpha)q and PLCbeta proteins. Since high glucose has been reported to increase the levels of vasoactive peptides and oxidative stress, the present study was undertaken to i
PMID 20393598

Japanese Journal

Evaluation of Material Constants and Temperature Properties in Lanthanum Calcium Oxoborate LaCa4O(BO3)3 Single Crystals

Shimizu Hiroyuki,Kodama Kaoru,Takeda Hiroaki [他],Nishida Takashi,Shikida Takashi,Okamura Soichiro,Shiosaki Tadashi
Japanese journal of applied physics. Pt. 1, Regular papers & short notes 43(9B), 6716-6720, 2004-09-15
… The normalized first-order temperature coefficients of some constants e.g., ${\varepsilon_{11}}^{T}$, ${\varepsilon_{22}}^{T}$, ${\varepsilon_{33}}^{T}$ and ${\varepsilon_{13}}^{T}$ determined at 10 kHz were 56.30, $-273.6$, 135.8 and $-258.4$ and $d_{11}$ and $d_{12}$ were $-408.3$ and 83.60 ppm/°C, respectively. …
NAID 150000043961

Direct activation of trpl cation channels by G alpha 11 subunits

AG Obukhov
EMBO J 15, 5833-5838, 1996
NAID 80009293339

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