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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/11/06 20:30:52」(JST)

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Eggerthella is a bacterial genus of Actinobacteria, in the family Coriobacteriaceae. Members of this genus are anaerobic, non-sporulating, non-motile, Gram-positive bacilli that grow singly, as pairs, or in short chains. They are found in the human colon and feces and have been implicated as a cause of ulcerative colitis, liver and anal abscesses and systemic bacteremia.^[1]^[2]

The type strain for this genus, Eggerthella lenta, was known as Eubacterium lentum prior to 1999.^[3]^[4] The genus is named for Arnold Eggerth, who first described the organism in 1935.^[5]

References

^ Lau, S. K.P.; P. C.W. Woo, A. M.Y. Fung, K.M. Chan, G. K.S. Woo and K.Y. Yuen (2004). "Anaerobic, non-sporulating, Gram-positive bacilli bacteraemia characterized by 16S rRNA gene sequencing". J. Med. Microbiol. 53 (Pt 12): 1247–1253. doi:10.1099/jmm.0.45803-0. PMID 15585505. http://jmm.sgmjournals.org/cgi/content/full/53/12/1247#H8-12.
^ Lau, S.K.; P.C. Woo, G.K. Woo, A.M. Fung, M.K. Wong, K.M. Chan, D.M. Tam and K.Y. Yuen (2004). "Eggerthella hongkongensis sp. nov. and Eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia". Diagn. Microbiol. Infect. Dis. 49 (4): 255–263. doi:10.1016/j.diagmicrobio.2004.04.012. PMID 15313530.
^ Kageyama, A.; Y. Benno and T. Nakase (1999). "Phylogenetic evidence for the transfer of Eubacterium lentum to the genus Eggerthella as Eggerthella lenta gen. nov., comb. nov". Int. J. Syst. Bacteriol 49 (4): 1725–1732. doi:10.1099/00207713-49-4-1725. PMID 10555354. http://ijs.sgmjournals.org/cgi/content/abstract/49/4/1725.
^ Moore, W. E. C; E.P. Cato and L.V. Holdeman (1971). "Eubacterium lentum (Eggerth) Prevot 1938: emendation of description and designation of the neotype strain". Int. J. Syst. Bacteriol. 21 (4): 299–303. doi:10.1099/00207713-21-4-299.
^ Eggerth, A. (September 1935). "The Gram-positive Non-spore-bearing Anaerobic Bacilli of Human Feces". J. Bacteriol. 30 (3): 277–299. PMC 543656. PMID 16559837. http://jb.asm.org/cgi/reprint/30/3/277.pdf.

External links

Euzéby, J.P. (2007). "Eggerthella". List of Prokaryotic names with Standing in Nomenclature. http://www.bacterio.cict.fr/e/eggerthella.html. Retrieved 2007-11-23.

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1. 腸球菌における抗菌薬耐性の機構 mechanisms of antibiotic resistance in enterococci

English Journal

The meddling microbes midst our medicines.

Viswanathan V.SourceSchool of Animal and Comparative Biomedical Sciences; University of Arizona; Tucson, AZ USA.
Gut microbes.Gut Microbes.2013 Aug 22;4(5). [Epub ahead of print]
It is not surprising that the complex metabolic machinery of the gut microbiome has accidental, or directed, ability to alter our medicines and influence their efficacy. What is not known is the extent to which this has contributed to drug failures or contraindications, or to the derailment of clini
PMID 23969979

Comparative in-vitro activity of SMT19969, a new antimicrobial agent, against Clostridium difficile and 350 Gram-positive and negative aerobic and anaerobic intestinal flora isolates.

Goldstein EJ, Citron DM, Tyrrell KL, Merriam CV.SourceR. M. Alden Research Laboratory, Culver City, CA 90230.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2013 Jul 22. [Epub ahead of print]
The comparative in vitro activity of SMT19969, a novel, narrow spectrum, non-absorbable agent, was studied against 50 ribotype defined C. difficile strains plus 174 Gram-positive and 136 Gram-negative intestinal anaerobes and 40 Gram-positive aerobes. SMT19969 was one dilution more active against C.
PMID 23877700

Isolation and characterization of novel S-equol-producing bacteria from brines of stinky tofu, a traditional fermented soy food in Taiwan.

Abiru Y, Ueno T, Uchiyama S.SourceSaga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd , Saga , Japan.
International journal of food sciences and nutrition.Int J Food Sci Nutr.2013 Jul 22. [Epub ahead of print]
Abstract Six strains capable of transforming daidzein to S-equol were isolated from the fermented brines of stinky tofu purchased in Taiwan. Daidzein was completely converted into S-equol within 24h of incubation in five strains. All the strains were gram-positive, rod-shaped, obligately anaerobic,
PMID 23869769

Japanese Journal

Solobacterium moorei 敗血症の1例 : 本邦初の報告症例と菌株の特徴について

森早苗,渡智久,安田篤志,三浦佐知子,尾栢隆,畑中宗博,大楠清文
日本臨床微生物学雑誌 = The journal of the Japanese Society for Clinical Microbiology 18(4), 236-244, 2008-12-25
NAID 10024961120

Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces

YOKOYAMA Shin-ichiro,SUZUKI Tohru
Bioscience, biotechnology, and biochemistry 72(10), 2660-2666, 2008-10-23
… It was most closely related to Eggerthella hongkongensis HKU10, with 93.3% 16S rDNA nucleotide sequence homology. … Based on these features, the isolate was identified as a novel species of the genus Eggerthella. … It was named Eggerthella sp. …
NAID 10027533138

Related Pictures

★リンクテーブル★

リンク元	「無芽胞嫌気性菌感染症」

「無芽胞嫌気性菌感染症」

Eggerthella
Scientific classification
Kingdom:	Bacteria
Phylum:	Actinobacteria
Class:	Actinobacteria
Order:	Coriobacteriales
Family:	Coriobacteriaceae
Genus:	Eggerthella
Species
	Eggerthella hongkongensis; Eggerthella lenta; Eggerthella sinensis

　　[★]

英: nonsporulating anaerobic infection, nonspore-forming anaerobic bacterial infection
関: バクテロイデス属

無芽胞嫌気性菌が関与する嫌気性菌感染症。
多くの細菌が関与するが、嫌気性のグラム陰性桿菌が多い。

嫌気性グラム陰性桿菌：Bacteroides、Prevotella、Fusobacterium、Porphyromonas、Bilophila
嫌気性グラム陽性球菌：Finegoldia、Micromonas、Peptostreptococcus
免疫不全状態時(嫌気性グラム陽性桿菌)：Eggerthella、Eubacterium、Propionibacterium

ヒトの常在菌でである(内因性感染となる)が、免疫力の低下や組織・器官の奇形が存在する場合、病変を形成しやすい。
好気性菌との複合感染をとる。
嫌気性グラム陰性桿菌は、カルバペネム、セファマイシンなど一部を除くほとんど全てのβ-ラクタム薬を分解するβ-ラクタマーゼを産生する。(嫌気性なので当然)Bacteroides fragilisにアミノグリコシド系抗菌薬は無効である。
治療：クリンダマイシン、リンコマイシン

[0] Lau, S. K.P.; P. C.W. Woo, A. M.Y. Fung, K.M. Chan, G. K.S. Woo and K.Y. Yuen (2004). "Anaerobic, non-sporulating, Gram-positive bacilli bacteraemia characterized by 16S rRNA gene sequencing". J. Med. Microbiol. 53 (Pt 12): 1247–1253. doi:10.1099/jmm.0.45803-0. PMID 15585505. http://jmm.sgmjournals.org/cgi/content/full/53/12/1247#H8-12.

[1] Lau, S.K.; P.C. Woo, G.K. Woo, A.M. Fung, M.K. Wong, K.M. Chan, D.M. Tam and K.Y. Yuen (2004). "Eggerthella hongkongensis sp. nov. and Eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia". Diagn. Microbiol. Infect. Dis. 49 (4): 255–263. doi:10.1016/j.diagmicrobio.2004.04.012. PMID 15313530.

[kageyama-2] Kageyama, A.; Y. Benno and T. Nakase (1999). "Phylogenetic evidence for the transfer of Eubacterium lentum to the genus Eggerthella as Eggerthella lenta gen. nov., comb. nov". Int. J. Syst. Bacteriol 49 (4): 1725–1732. doi:10.1099/00207713-49-4-1725. PMID 10555354. http://ijs.sgmjournals.org/cgi/content/abstract/49/4/1725.

[3] Moore, W. E. C; E.P. Cato and L.V. Holdeman (1971). "Eubacterium lentum (Eggerth) Prevot 1938: emendation of description and designation of the neotype strain". Int. J. Syst. Bacteriol. 21 (4): 299–303. doi:10.1099/00207713-21-4-299.

[4] Eggerth, A. (September 1935). "The Gram-positive Non-spore-bearing Anaerobic Bacilli of Human Feces". J. Bacteriol. 30 (3): 277–299. PMC 543656. PMID 16559837. http://jb.asm.org/cgi/reprint/30/3/277.pdf.

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Eggerthella