参考

1.

http://blog.goo.ne.jp/matsubomb/e/f0be423c42fa63540ff520756ed4ee7a

2. Early goal-directed therapy in the treatment of severe sepsis and septic shock.

Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group.SourceDepartment of Emergency Medicine, Henry Ford Health Systems, Case Western Reserve University, Detroit, MI 48202, USA. erivers1@hfhs.org
The New England journal of medicine.N Engl J Med.2001 Nov 8;345(19):1368-77.
BACKGROUND: Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand. The purpose of this study was to evaluate the efficacy of
PMID 11794169

WordNet

very young; "at an early age"
before the usual time or the time expected; "she graduated early"; "the house was completed ahead of time" (同)ahead of time, too soon
in good time; "he awoke betimes that morning" (同)betimes
belonging to the distant past; "the early inhabitants of Europe"; "former generations"; "in other times" (同)former, other
at or near the beginning of a period of time or course of events or before the usual or expected time; "early morning"; "an early warning"; "early diagnosis"; "an early death"; "took early retirement"; "an early spring"; "early varieties of peas and tomatoes mature before most standard varieties"
being or occurring at an early stage of development; "in an early stage"; "early forms of life"; "early man"; "an early computer"
expected in the near future; "look for an early end to the negotiations"
of an early stage in the development of a language or literature; "the Early Hebrew alphabetical script is that used mainly from the 11th to the 6th centuries B.C."; "Early Modern English is represented in documents printed from 1476 to 1700"
a successful attempt at scoring; "the winning goal came with less than a minute left to play"
game equipment consisting of the place toward which players of a game try to advance a ball or puck in order to score points
the state of affairs that a plan is intended to achieve and that (when achieved) terminates behavior intended to achieve it; "the ends justify the means" (同)end
(medicine) the act of caring for someone (as by medication or remedial training etc.); "the quarterback is undergoing treatment for a knee injury"; "he tried every treatment the doctors suggested"; "heat therapy gave the best relief"
manageable by a supervising agent; "a directed program of study"
(often used in combination) having a specified direction; "a positively directed vector"; "goal-directed"
a state of southwestern India; a former Portuguese colony

PrepTutorEJDIC

(時間・時期が)『早い』,『初期の』 / 昔の / (普通より,予定より)早い / 近い将来の / (時間・時期的に)『早く』 / (予定・ふだんより)早く
『ゴール』,決勝点 / (ゴールに球を入れて得た)得点 / =goalkeeper / 『目標』(aim),目的;目的地
(病気の)治療,療法 / =psychotherapy

UpToDate Contents

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1. 成人における重症敗血症および敗血症性ショックの評価およびマネージメント evaluation and management of severe sepsis and septic shock in adults
2. 小児におけるショックの初期マネージメント initial management of shock in children
3. 敗血症性ショック：小児における迅速な覚知および初期蘇生 septic shock rapid recognition and initial resuscitation in children
4. 敗血症および全身性炎症反応症候群：定義、疫学、および予後 sepsis and the systemic inflammatory response syndrome definitions epidemiology and prognosis
5. 乳酸アシドーシスの原因 causes of lactic acidosis

English Journal

Monoclonal Antibodies for the Immunotherapy of Solid Tumours.

Mauerer R, Gruber R.Sourcesynlab MVZ Labor München Zentrum GbR, Bayerstraße 5380335 München. rudolf.gruber@synlab.com.
Current pharmaceutical biotechnology.Curr Pharm Biotechnol.2012 Feb 14. [Epub ahead of print]
More than 80% of all cancers are caused by solid malignancies. More than 90% of these tumours are of epithelial origin. The main principles in tumour treatment are surgery, radiotherapy, chemotherapy or combinations of these. Complete surgical removal of the tumour is the most effective therapy for
PMID 22339220

Masseter tissue oxygen saturation predicts normal central venous oxygen saturation during early goal-directed therapy and predicts mortality in patients with severe sepsis.

Colin G, Nardi O, Polito A, Aboab J, Maxime V, Clair B, Friedman D, Orlikowski D, Sharshar T, Annane D.SourceGeneral Intensive Care Unit, Raymond Poincaré Hospital (AP-HP), Garches, France.
Critical care medicine.Crit Care Med.2012 Feb;40(2):435-40.
OBJECTIVE: This study aimed to investigate, in patients with severe sepsis, the correlation between central venous oxygen saturation and tissue oxygen saturation at different levels.DESIGN: Prospective observational study.SETTING: General intensive care unit at an academic medical center in France.P
PMID 22020233

The impact of emergency medical services on the ED care of severe sepsis.

Studnek JR, Artho MR, Garner CL Jr, Jones AE.SourceDepartment of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA.
The American journal of emergency medicine.Am J Emerg Med.2012 Jan;30(1):51-6. Epub 2010 Oct 27.
OBJECTIVE: The identification and treatment of critical illness is often initiated by emergency medical services (EMS) providers. We hypothesized that emergency department (ED) patients with severe sepsis who received EMS care had more rapid recognition and treatment compared to non-EMS patients.MET
PMID 21030181

The degree of bandemia in septic ED patients does not predict inpatient mortality.

Ward MJ, Fertel BS, Bonomo JB, Smith CL, Hart KW, Lindsell CJ, Wright SW.SourceDepartment of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267-0769, USA. mward04@gmail.com
The American journal of emergency medicine.Am J Emerg Med.2012 Jan;30(1):181-3. Epub 2010 Oct 20.
BACKGROUND: A delay in diagnosis of sepsis and appropriate treatment increases subsequent mortality. An association with the degree of bandemia, or the presence of immature neutrophils in the white blood cell count, has not been explored in septic patients presenting to the emergency department (ED)
PMID 20970296