- 同
- cyclic adenosine monophosphate
WordNet
- give an artificially banal or sexual quality to
- temporary living quarters specially built by the army for soldiers; "wherever he went in the camp the men were grumbling" (同)encampment, cantonment, bivouac
- shelter for persons displaced by war or political oppression or for religious beliefs (同)refugee camp
- a site where care and activities are provided for children during the summer months; "city kids get to see the country at a summer camp" (同)summer camp
- a penal institution (often for forced labor); "China has many camps for political prisoners"
- temporary lodgings in the country for travelers or vacationers; "level ground is best for parking and camp areas"
- a group of people living together in a camp; "the whole camp laughed at his mistake"
- something that is considered amusing not because of its originality but because of its unoriginality; "the living room was pure camp"
- establish or set up a camp (同)camp down
- providing sophisticated amusement by virtue of having artificially (and vulgarly) mannered or banal or sentimental qualities; "they played up the silliness of their roles for camp effect"; "campy Hollywood musicals of the 1940s" (同)campy
- live in or as if in a tent; "Can we go camping again this summer?"; "The circus tented near the town"; "The houseguests had to camp in the living room" (同)encamp, camp out, bivouac, tent
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- 〈C〉(軍隊・登山隊・探検隊などの)『野営地』 / 〈C〉〈U〉野営のテント,仮設小屋 / 〈U〉野営,キャンプ[生活];軍隊生活 / 〈C〉夏季キャンプ場,サマーキャンプ / 《集合的に》野営する人たち,キャンプする人たち / 〈C〉(主義・信条などを同じくする)同志たち,同じ陣営;同じ立場 / 『野営する』,キャンプ生活を送る《+『out』》
- =homosexual / (男性が)女々しい / すたれた,古めかしい
- =sense organ / 受信装置
- California
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/12/08 03:16:55」(JST)
[Wiki en表示]
Slime mold cyclic AMP receptor |
Identifiers |
Symbol |
Dicty_CAR |
Pfam |
PF05462 |
Pfam clan |
CL0192 |
InterPro |
IPR000848 |
PROSITE |
PDOC00691 |
Available protein structures: |
Pfam |
structures |
PDB |
RCSB PDB; PDBe; PDBj |
PDBsum |
structure summary |
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Cyclic AMP receptors from slime molds are a distinct family of G-protein coupled receptors. These receptors control development in Dictyostelium discoideum.
The cyclic AMP receptors coordinate aggregation of individual cells into a multicellular organism, and regulate the expression of a large number of developmentally-regulated genes.[1][2][3] The amino acid sequences of the receptors contain high proportions of hydrophobic residues grouped into 7 domains, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins. However, while a similar 3D framework has been proposed to account for this, there is no significant sequence similarity between these families: the cAMP receptors thus bear their own unique '7TM' signature.
See also
References
- ^ Devreotes PN, Kimmel AR, Johnson RL, Klein PS, Sun TJ, Saxe III CL (1988). "A chemoattractant receptor controls development in Dictyostelium discoideum". Science 241 (4872): 1467–1472. doi:10.1126/science.3047871. PMID 3047871.
- ^ Ginsburg GT, Louis JM, Johnson R, Devreotes PN, Kimmel AR, Saxe III CL (1993). "CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum". Genes Dev. 7 (2): 262–272. doi:10.1101/gad.7.2.262. PMID 8436297.
- ^ Devreotes PN, Kimmel AR, Johnson RL, Gollop R, Saxe III CL (1993). "Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development". Genes Dev. 7 (2): 273–282. doi:10.1101/gad.7.2.273. PMID 8382181.
Membrane proteins, receptors: cell surface receptors
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G protein-coupled receptor |
Class A |
- Eicosanoid receptor (Prostaglandin receptor)
- Protease-activated receptor
- Neurotransmitter receptor
- Purinergic receptor
- Biogenic amine receptor
- Olfactory receptor
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Class B |
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Class C |
- Metabotropic glutamate receptor
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Class D |
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Class E |
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Class F |
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Ligand-gated ion channel |
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Enzyme-linked receptor |
- Serine/threonine-specific protein kinase
- Receptor tyrosine kinase
- Guanylate cyclase
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Other/ungrouped |
- Asialoglycoprotein receptor
- Tumor necrosis factor receptor
- Immunoglobulin superfamily
- N-Acetylglucosamine receptor
- Neuropilins
- Transferrin receptor
- EDAR
- Lipoprotein receptor-related protein
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- See also
- cell surface receptor deficiencies
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
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UpToDate Contents
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English Journal
- Cell-based high-throughput odorant screening system through visualization on a microwell array.
- Oh EH, Lee SH, Lee SH, Ko HJ, Park TH.SourceInterdisciplinary Program of Bioengineering, Seoul, National University, Seoul, Republic of Korea.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Mar 15;53:18-25. doi: 10.1016/j.bios.2013.09.039. Epub 2013 Sep 25.
- The development of a cell-based high-throughput screening system has attracted much attention from researchers who study drug screening mechanisms and characterization of G-protein coupled receptors (GPCRs). Although olfactory receptors (ORs) constitute the largest group of GPCRs that play a critica
- PMID 24103575
- Induction of Dopaminergic Neurons From Human Wharton's Jelly Mesenchymal Stem Cell by Forskolin.
- Paldino E, Cenciarelli C, Giampaolo A, Milazzo L, Pescatori M, Hassan HJ, Casalbore P.SourceInstitute of Cell Biology and Neurobiology, National Research Council, Rome, Italy.
- Journal of cellular physiology.J Cell Physiol.2014 Feb;229(2):232-44. doi: 10.1002/jcp.24442.
- The purpose of this study was to investigate the Wharton's jelly mesenchymal stem cells differentiation ability toward neuronal fate. Human Wharton's jelly mesenchymal stem cells (hWJMSC) have been isolated from human umbilical cord of full-term births and characterized by flow cytometry analysis fo
- PMID 23893793
- Glutamate receptors and the regulation of steroidogenesis in the human adrenal gland: The metabotropic pathway.
- Felizola SJ, Nakamura Y, Satoh F, Morimoto R, Kikuchi K, Nakamura T, Hozawa A, Wang L, Onodera Y, Ise K, McNamara KM, Midorikawa S, Suzuki S, Sasano H.SourceDepartment of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Jan 25;382(1):170-7. doi: 10.1016/j.mce.2013.09.025. Epub 2013 Sep 27.
- BACKGROUND: l-glutamate is a major excitatory neurotransmitter in the mammalian brain. Glutamate receptors have been reported in the rat adrenal cortex and in human aldosterone-producing adenomas (APA). However, details regarding the expression levels and functions of these receptors in human adreno
- PMID 24080311
Japanese Journal
- Ca(2+)-dependent binding of calcium-binding protein 1 to presynaptic group III metabotropic glutamate receptors and blockage by phosphorylation of the receptors.
- Nakajima Yoshiaki
- Biochemical and biophysical research communications 412(4), 602-605, 2011-09-09
- … Presynaptic group III metabotropic glutamate receptors (mGluRs) and Ca(2+) channels are the main neuronal activity-dependent regulators of synaptic vesicle release, and they use common molecules in their signaling cascades. … Here I show that calcium-binding protein 1 (CaBP1) bound to presynaptic group III mGluRs competitively with CaM in a Ca(2+)-dependent manner and that this binding was blocked by protein kinase C (PKC)-mediated phosphorylation of these receptors. …
- NAID 80021990000
- Multiple noncoding exons 1 of nuclear receptors NR4A family (nerve growth factor-induced clone B, Nur-related factor 1 and neuron-derived orphan receptor 1) and NR5A1 (steroidogenic factor 1) in human cardiovascular and adrenal tissues
- Demura Masashi,Wang Fen,Yoneda Takashi,Karashima Shigehiro,Mori Shunsuke,Oe Masashi,Kometani Mitsuhiro,Sawamura Toshitaka,Cheng Yuan,Maeda Yuji,Namiki Mikio,Ino Hidekazu,Fujino Noboru,Uchiyama Katsuharu,Tsubokawa Toshinari,Yamagishi Masakazu,Nakamura Yasuhiro,Ono Katsuhiko,Sasano Hironobu,Demura Yoshiki,Takeda Yoshiyu
- Journal of Hypertension 29(6), 1185-1195, 2011-06
- … Objective: Nuclear receptors are involved in a wide variety of functions, including aldosteronogenesis. … The present study was undertaken to elucidate the mechanism of differential regulation of nuclear receptors between cardiovascular and adrenal tissues. … Results: In adrenocortical H295R cells, angiotensin II, KCl or cAMP, all stimulated CYP11B2 transcription and NR4A was upregulated, whereas NR2F and NR5A1 were downregulated. …
- NAID 120003141563
Related Links
- 1. Acta Biochim Biophys Sin (Shanghai). 2008 Jul;40(7):651-62. Epac and PKA: a tale of two intracellular cAMP receptors. Cheng X, Ji Z, Tsalkova T, Mei F. cAMP-mediated signaling pathways regulate a multitude of important ...
- Receptors, Cyclic Amp; Cyclic AMP Receptors; cAMP Receptors. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between ...
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環状アデノシン一リン酸 サイクリックAMP 環状AMP adenosine 3',5'-cyclic monophosphate, cyclic AMP
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