C3a
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
PrepTutorEJDIC
- carbonの化学記号
UpToDate Contents
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English Journal
- Decreased expression of complement 3a receptor (C3aR) in human placentas from severe preeclamptic pregnancies.
- Lim R, Lappas M.SourceDepartment of Obstetrics and Gynaecology, University of Melbourne, Victoria, Australia; Mercy Perinatal Research Centre, Mercy Hospital for Women, Heidelberg, Victoria, Australia.
- European journal of obstetrics, gynecology, and reproductive biology.Eur J Obstet Gynecol Reprod Biol.2012 Dec;165(2):194-8. doi: 10.1016/j.ejogrb.2012.08.003. Epub 2012 Aug 16.
- OBJECTIVES: The aim of this study was to determine the expression of the anaphylatoxin receptors complement C3a receptor (C3aR) and C5a receptor (C5aR) in the placentas of pregnancies complicated by severe early onset preeclampsia.STUDY DESIGN: We recruited women with pregnancies complicated by seve
- PMID 22901903
- Complement regulation of T cell immunity.
- Kwan WH, van der Touw W, Heeger PS.SourceDepartment of Medicine, Recanati Miller Transplant Institute and Immunology Institute, Mount Sinai School of Medicine, Box 1243, One Gustave L. Levy Plaza, New York, NY 10029, USA.
- Immunologic research.Immunol Res.2012 Dec;54(1-3):247-53. doi: 10.1007/s12026-012-8327-1.
- Results of studies published since 2002 reveal that T cells and antigen-presenting cells (APCs) produce complement proteins. The immune cell-derived, alternative pathway complement components activate spontaneously, yielding local, but not systemic, production of C3a and C5a. These anaphylatoxins bi
- PMID 22477527
Japanese Journal
- Complement inhibition alleviates paraquat-induced acute lung injury
- 日本毒性学会学術年会 39.2(0), AS1-2, 2012
- … Expression of the anaphylatoxin receptors, C3aR and C5aR, was also increased. … A similar therapeutic effect was also observed by treatment with either C3a receptor antagonist or a blocking C5a receptor monoclonal antibody. …
- NAID 130005009266
- 抗C4抗体を有し新鮮凍結血漿の投与でアナフィラキシー様反応を来した1例
- 鬼松 幸子,内田 立身,氏家 知佳,山本 直子,舩本 康申,小河 敏伸,本田 豊彦
- 日本輸血細胞治療学会誌 58(6), 760-764, 2012
- 新鮮凍結血漿(Fresh Frozen Plasma:FFP)の投与によりアナフィラキシー様反応を来し,検索の結果,抗C4抗体(IgGクラス)が関与した可能性が示唆された症例を経験した.さらに本例では輸血後にトリプターゼ値上昇,好酸球増多がありIgE値が高く,好酸球・好塩基球・肥満細胞の脱顆粒により生じたmediatorによるアナフィラキシー様反応を起こした可能性も示唆された. 症例は79歳男性, …
- NAID 130004542677
- Effect of the C3a-Receptor Antagonist SB 290157 on Anti-OVA Polyclonal Antibody-Induced Arthritis
- , , [他], , , ,
- Journal of Pharmacological Sciences 112(1), 56-63, 2010
- … It was investigated whether the C3a-receptor antagonist (C3aRA) SB 290157 was involved in the suppression of anti-OVA pAb–induced arthritis because it is well known that anaphylatoxin C3a plays a crucial role in the development of an effective inflammatory response during complement activation. …
- NAID 130000148442
Related Links
- The complement system forms the central core of innate immunity but also mediates a variety of inflammatory responses. Anaphylatoxin C3a, which is generated as a byproduct of complement activation, has long been known to ...
- Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. ... Gene ID: 719, updated on 6-Oct-2013 Summary Other designations C3a anaphylatoxin chemotactic receptor, C3a-R, complement component 3 receptor 1
★リンクテーブル★
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- 同
- 補体第三成分 third component of complement
- 関
- 補体、C3a, C3b
- 補体の一つ
- C3は血清中に最も多く存在する
- C3 convertaseによってC3aとC3bを生じる
- C3 convertase活性を持つのは2つ
- 1. C4bC2a (古典的経路)
- 2. C3bBbP (別経路)
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[★]
- 同
- C3aアナフィラトキシン C3a anaphylatoxin
- 関
- 補体
機能
- 活性はC5aの約1/200 (SMB.35)