Best disease



  1. it would be sensible; "youd best stay at home"
  2. the supreme effort one can make; "they did their best"
  3. the person who is most outstanding or excellent; someone who tops all others; "he could beat the best of them" (同)topper
  4. (superlative of `good'
  5. in a most excellent way or manner; "he played best after a couple of martinis"
  6. an impairment of health or a condition of abnormal functioning
  7. caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
  8. Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978) (同)C. H. Best, Charles Herbert Best


  1. (『good』の最上級;比較級は『better』)『いちばんよい』,最もよい,最良の / (『well』の最上級;比較級は『better』)『健康状態が最良の』(healthiest) / 最大の,大部分の / 《話》(反語的に)きわめてひどい,徹底した / (『well』の最上級;比較級は『better』)『いちばんよく』,最もよく,最も / 《通例過去分詞と結合して形容詞を作って》最もよく / 『最上』,最善,最良;最もすぐれた人々(物) / (…の)『最もよいもの』(部分)《+『of』+『名』》
  2. (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
  3. 女性の話術芸人 =diseur
  4. 病気にかかった / 病的な,不健全な(morbid)
  5. berylliumの化学記号

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/26 23:12:36」(JST)

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English Journal

  • Alternative splicing of the neurofibromatosis type I pre-mRNA.
  • Barron VA, Lou H.SourceDepartment of Genetics, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
  • Bioscience reports.Biosci Rep.2012 Apr 1;32(2):131-8.
  • NF1 (neurofibromatosis type I) is a common genetic disease that affects one in 3500 individuals. The disease is completely penetrant but shows variable phenotypic expression in patients. NF1 is a large gene, and its pre-mRNA undergoes alternative splicing. The NF1 protein, neurofibromin, is involve
  • PMID 22115364
  • Milk, milk products, and disease free health: an updated overview.
  • Nagpal R, Behare PV, Kumar M, Mohania D, Yadav M, Jain S, Menon S, Parkash O, Marotta F, Minelli E, Henry CJ, Yadav H.Sourcea Department of Biotechnology, School of Technology and Science , Lovely Professional University , Phagwara , Punjab , India.
  • Critical reviews in food science and nutrition.Crit Rev Food Sci Nutr.2012 Apr;52(4):321-33.
  • The cow and its milk have been held sacred in the world since the dawn of human civilization. Indian ancient Vedic texts describe the virtues of milk and dairy products, as is authenticated by modern scientific principles and proofs. Therefore, milk has been considered as one of the most natural and
  • PMID 22332596
  • Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors.
  • Pineda D, Ampurdanés C, Medina MG, Serratosa J, Tusell JM, Saura J, Planas AM, Navarro P.SourceCancer Research Programme, IMIM-Hospital del Mar, C/ Dr. Aiguader 88, 08003 Barcelona, Spain; Center for Genomic Regulation (CRG), C/ Dr. Aiguader 88, 08003 Barcelona, Spain.
  • Glia.Glia.2012 Apr;60(4):526-40. doi: 10.1002/glia.22284. Epub 2011 Dec 7.
  • Inflammatory responses mediated by glial cells play a critical role in many pathological situations related to neurodegeneration such as Alzheimer's disease. Tissue plasminogen activator (tPA) is a serine protease which best-known function is fibrinolysis, but it is also involved in many other physi
  • PMID 22162045

Japanese Journal

  • 器質性視覚障害と心因性視覚障害を合併した1例
  • 大平 明彦
  • 東京女子医科大学雑誌 82(E1), E178-E182, 2012-01-31
  • 成人患者において詐病あるいは心因性視覚障害を診断することはしばしば困難であるが、とくに明瞭な眼疾患に伴った場合は難しい。症例は、38歳の女性で、17年前に両眼の網膜剥離手術を受け,1年以上前から左眼視力の低下を自覚し受診した。初診時左眼の最良矯正視力はハードコンタクトレンズ装用下で(0.2)であった。眼底には、過去の網脈絡膜瘢痕が眼底の下方中間部にあるのみで、黄斑部に異常所見はなかった。中心フリッ …
  • NAID 110008767971
  • 5.先天性心疾患合併小児外科疾患の治療戦略 : 小児外科医の立場から(<特集>先天性心疾患合併小児外科疾患の最新の治療戦略)
  • Examination of validity of fall risk assessment items for screening high fall risk elderly among the healthy community-dwelling Japanese population
  • Demura Shinichi,Sato Susumu,Yamaji Shunsuke,Kasuga Kosho,Nagasawa Yoshinori
  • Archives of Gerontology and Geriatrics 53(1), e41-e45, 2011-07
  • … This study used fall experience and 50 fall risk assessment items representing the five risk factors (symptoms of falling, physical function, disease and physical symptom, environment, and behavior and character), as we described before. … This percentage, when using each risk factor score as an independent variable, was 42.5% (symptom of falling), 0.6% (physical function score), 0.6% (disease and physical symptoms score), 0.0% (environment score), and 1.1% (behavior and character score), respectively. …
  • NAID 120002661939

Related Links

Best disease, also termed vitelliform macular dystrophy, is typically an autosomal dominant disorder, which classically presents in childhood with the striking appearance of a yellow or orange yolklike lesion in the macula. Dr Franz Best, a German ophthalmologist, described the first pedigree in 1905.
EyeWiki, the Eye Encyclopedia written by Eye Physicians & Surgeons. ... Disease Entity Best disease, or Vitelliform dystrophy, is a hereditary retinal dystrophy involving the retinal pigment epithelium (RPE), and leads to a ...

Related Pictures

Best DiseaseBest Disease - Left Eye Treated Previously Best diseaseBest diseaseBest disease2Best Disease







retinal degeneration







Best disease
卵黄状黄斑変性 vitelliform macular dystrophy
  • AD。学童期頃に発症。黄斑部に卵黄様の黄色色調滲出病変を呈し、黄斑部の萎縮をきたす。ERGは正常だが、EOGは著しい異常(平坦型)を示す。
  • 黄斑の下部にリポフスチンが沈着し、細胞を障害して視力障害をきたす。夜盲や周辺視野の低下はない。


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  • n.
疾患illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
  • something that is very wrong with people's attitudes, way of life or with society.
ailailmentdisease entitydisorderillillnessmaladysicksickness
  • 注意




  • adj.
  • adv




Beta-Blocker Evaluation of Survival Trial


  [★] ベリリウム beryllium