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1. 成人における再発性カルシウム結石の予防 prevention of recurrent calcium stones in adults
2. 大量輸血 massive blood transfusion
3. クエン酸クロミフェンによる排卵誘発 ovulation induction with clomiphene citrate
4. アフェレシス治療（血漿交換または血球アフェレシス）：合併症 therapeutic apheresis plasma exchange or cytapheresis complications
5. まれな先天性副腎過形成 uncommon congenital adrenal hyperplasias

Role of malate transporter in lipid accumulation of oleaginous fungus Mucor circinelloides.

Zhao L1, Cánovas-Márquez JT2, Tang X1, Chen H1,3, Chen YQ1,3, Chen W1,3, Garre V4, Song Y5, Ratledge C6.
Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2016 Feb;100(3):1297-305. doi: 10.1007/s00253-015-7079-y. Epub 2015 Oct 28.
Fatty acid biosynthesis in oleaginous fungi requires the supply of reducing power, NADPH, and the precursor of fatty acids, acetyl-CoA, which is generated in the cytosol being produced by ATP: citrate lyase which requires citrate to be, transported from the mitochondrion by the citrate/malate/pyruva
PMID 26512004

Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid.

Vu CB, Bemis JE, Benson E, Bista P, Carney D, Fahrner R, Lee D, Liu F, Lonkar P, Milne JC, Nichols AJ, Picarella D, Shoelson A, Smith J, Ting A, Wensley A, Yeager M, Zimmer M, Jirousek MR.
Journal of medicinal chemistry.J Med Chem.2016 Jan 19. [Epub ahead of print]
This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. These molecular entities were created by covalently linking two bioactive molecules - either niacin or salicylic acid to an omega-3 fatty acid.
PMID 26784936

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

Peleg S1, Feller C2, Forne I3, Schiller E4, Sévin DC5, Schauer T2, Regnard C2, Straub T6, Prestel M2, Klima C1, Schmitt Nogueira M1, Becker L4, Klopstock T7, Sauer U8, Becker PB2, Imhof A9, Ladurner AG10.
EMBO reports.EMBO Rep.2016 Jan 18. pii: e201541132. [Epub ahead of print]
Old age is associated with a progressive decline of mitochondrial function and changes in nuclear chromatin. However, little is known about how metabolic activity and epigenetic modifications change as organisms reach their midlife. Here, we assessed how cellular metabolism and protein acetylation c
PMID 26781291

Genetic Evidence for Bacterial Chemolithoautotrophy Based on the Reductive Tricarboxylic Acid Cycle in Groundwater Systems

ALBINALFREIDER,VOGT CARSTEN
Microbes and environments 27(2), 209-214, 2012-06-01
… Geologically and chemically distinct aquifers were screened for the presence of two genes coding for key enzymes of the reverse tricarboxylic acid (rTCA) cycle in autotrophic bacteria, 2-oxoglutarate : ferredoxin oxidoreductase (oorA) and the beta subunit of ATP citrate lyase enzymes (aclB). …
NAID 10030432228

Bacterial Lifestyle in a Deep-sea Hydrothermal Vent Chimney Revealed by the Genome Sequence of the Thermophilic Bacterium Deferribacter desulfuricans SSM1

DNA Research 17(3), 123-137, 2010-06
… The reconstructed central metabolisms showed a heterotrophic lifestyle primarily driven by C1 to C3 organics, e.g. formate, acetate, and pyruvate, and also suggested that the inability of autotrophy via a reductive tricarboxylic acid cycle may be due to the lack of ATP-dependent citrate lyase. …
NAID 80021263581

Relationship between Garcinia cambogia-Induced Impairment of Spermatogenesis and Meiosis-Activating Sterol Production in Rat Testis

Kiyose Chikako,Ogino Satomi,Kubo Kazuhiro,Takeuchi Masaya,Saito Morio
Journal of Clinical Biochemistry and Nutrition 38(3), 180-187, 2006
… Garcinia cambogia (GA) is one such supplement, and its active component is (−)-hydroxycitric acid ((−)-HCA), a competitive inhibitor of ATP citrate lyase, which is responsible for producing acetyl CoA from citric acid. …
NAID 130004879078