英: fibrocartilaginous mesenchymoma

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1. 悪性肝腫瘍の病理pathology of malignant liver tumors [show details]
…complex tumor that may include fetal and/or embryonal hepatocytes and heterologous tissues, including cartilage, bone, striated muscle fibers, and squamous epithelium. Primary mesenchymal tumors arising …
2. 変形性関節症の病因pathogenesis of osteoarthritis [show details]
… activity in subchondral bone mesenchymal stem cells may play a role in promoting degradation of the overlying cartilage .… the joint surface, including the superficial zone chondrocytes, from shear stresses . The collagen fibers provide the tensile strength and form a network that restrains the very hydrophilic proteoglycans … including tumor necrosis factor (TNF)-alpha (elevated sixfold) and interleukin (IL) 6 (elevated 1000-fold),…
3. 骨格の正常な発達および骨形成ならびに骨吸収の調節normal skeletal development and regulation of bone formation and resorption [show details]
… The ends of epiphyses are covered with a hyaline cartilage ("articular cartilage").… multipotent mesenchymal stem cells, which also give rise to bone marrow stromal cells, chondrocytes, muscle cells, and adipocytes . Osteoblast progenitors may originate not only from stromal mesenchymal progenitors… for several days, which allows time for collagen cross-linking and the development of large, strong fibers. The Wnt signaling pathway is another critical regulator of skeletal development and mass, working …
4. 腱障害や筋障害への生物学的製剤の使用biologic therapies for tendon and muscle injury [show details]
… tissue (a process termed engrafting) and can include mesenchymal stem or stromal cells (MSCs),… pluripotent stem cells. By definition, MSCs must demonstrate in vitro differentiation into fat, bone, and cartilage ; however, MSCs are also capable of differentiation into muscle, tendon, and ligament to varying … involving local implantation to treat orthopedic conditions have not shown a significant risk of tumor formation, unintended differentiation, or other serious adverse events . Bone marrow aspirate has …
5. 肝臓芽細胞腫の概要overview of hepatoblastoma [show details]
… morphologically complex tumor that may include fetal and/or embryonal hepatocytes and heterologous tissues, including cartilage, bone, striated muscle fibers,… a mesenchymal component, most commonly osteoid tissue and rarely cartilage ,…