ムコール症。接合菌症
WordNet
- any fungal infection caused by fungi of the Phycomycetes group
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/02/18 04:54:29」(JST)
[Wiki en表示]
| Mucormycosis |
|
| Periorbital fungal infection known as mucormycosis, or phycomycosis |
| Classification and external resources |
| Specialty |
infectious disease |
| ICD-10 |
B46 |
| ICD-9-CM |
117.7 |
| DiseasesDB |
31329 |
| MedlinePlus |
000649 |
| eMedicine |
med/1513 med/2026 oph/225 ped/1488 |
| MeSH |
D020096 |
|
[edit on Wikidata]
|
Zygomycosis is the broadest term to refer to infections caused by bread mold fungi of the zygomycota phylum. However, because zygomycota has been identified as polyphyletic, and is not included in modern fungal classification systems, the diseases that zygomycosis can refer to are better called by their specific names: mucormycosis[1] (after Mucorales), phycomycosis[2] (after Phycomycetes) and basidiobolomycosis (after Basidiobolus).[3] These rare yet serious and potentially life-threatening fungal infections usually affect the face or oropharyngeal (nose and mouth) cavity.[4] Zygomycosis type infections are most often caused by common fungi found in soil and decaying vegetation. While most individuals are exposed to the fungi on a regular basis, those with immune disorders (immunocompromised) are more prone to fungal infection.[2][5][6] These types of infections are also common after natural disasters, such as tornadoes or earthquakes, where people have open wounds that have become filled with soil or vegetative matter.[7]
The condition may affect the gastrointestinal tract or the skin. In non-trauma cases, it usually begins in the nose and paranasal sinuses and is one of the most rapidly spreading fungal infections in humans.[2] Common symptoms include thrombosis and tissue necrosis.[8] Treatment consists of prompt and intensive antifungal drug therapy and surgery to remove the infected tissue.[9][10] The prognosis varies vastly depending upon an individual patient's circumstances.[8]
Contents
- 1 Causes
- 2 Other animals
- 3 Epidemiology
- 4 References
Causes
Micrograph showing a zygomycetes infection.
Pathogenic Zygomycosis is caused by species in two orders: Mucorales or Entomophthorales, with the former causing far more disease than the latter.[11] These diseases are known as "mucormycosis" and "entomophthoramycosis", respectively.[12]
- Order Mucorales (mucormycosis)
- Family Mucoraceae
- Absidia (Absidia corymbifera)
- Apophysomyces (Apophysomyces elegans and Apophysomyces trapeziformis)
- Mucor (Mucor indicus)
- Rhizomucor (Rhizomucor pusillus)
- Rhizopus (Rhizopus oryzae)
- Family Cunninghamellaceae
- Cunninghamella (Cunninghamella bertholletiae)
- Family Thamnidiaceae
- Cokeromyces (Cokeromyces recurvatus)
- Family Saksenaeaceae
- Saksenaea (Saksenaea vasiformis)
- Family Syncephalastraceae
- Syncephalastrum (Syncephalastrum racemosum)
- Order Entomophthorales (entomophthoramycosis)
- Family Basidiobolaceae
- Basidiobolus (Basidiobolus ranarum)
- Family Ancylistaceae
- Conidiobolus (Conidiobolus coronatus/Conidiobolus incongruus)
Other animals
The term oomycosis is used to describe oomycete infections.[13] These are more common in animals, notably dogs and horses. These are heterokonts, not true fungi. Types include pythiosis (caused by Pythium insidiosum) and lagenidiosis.
Zygomycosis has been described in a cat, where fungal infection of the tracheobronchus led to respiratory disease requiring euthanasia.[14]
Epidemiology
Zygomycosis has been found in survivors of the 2004 Indian Ocean earthquake and tsunami and in survivors of 2011 Joplin, Missouri tornado.[15]
References
- ^ Toro, Carlos; del Palacio, Amalia; Álvarez, Carmen; Rodríguez-Peralto, José Luis; Carabias, Esperanza; Cuétara, Soledad; Carpintero, Yolanda; Gómez, César (1998). "Zigomicosis cutánea por Rhizopus arrhizus en herida quirúrgica" [Cutaneous zygomycosis caused by Rhizopus arrhizus in a surgical wound]. Revista Iberoamericana de Micología (in Spanish). 15 (2): 94–6. PMID 17655419.
- ^ a b c Auluck, Ajit (2007). "Maxillary necrosis by mucormycosis. a case report and literature review" (PDF). Medicina Oral Patologia Oral y Cirugia Bucal. 12 (5): E360–4. PMID 17767099.
- ^ Centers for Disease Control and Prevention (1999). "Gastrointestinal Basidiobolomycosis — Arizona, 1994–1999". Morbidity and Mortality Weekly Report. 48 (32): 710–3. PMID 21033182.
- ^ Nancy F Crum-Cianflone; MD MPH. "Mucormycosis". eMedicine. Retrieved 2008-05-19.
- ^ "MedlinePlus Medical Encyclopedia: Mucormycosis". Retrieved 2008-05-19.
- ^ Ettinger, Stephen J.; Feldman, Edward C. (1995). Textbook of Veterinary Internal Medicine (4th ed.). W.B. Saunders Company. ISBN 0-7216-6795-3. [page needed]
- ^ Draper, Bill; Suhr, Jim (June 11, 2011). "Survivors of Joplin tornado develop rare infection". Seattle Post-Intelligencer. Associated Press.
- ^ a b Spellberg, B.; Edwards, J.; Ibrahim, A. (2005). "Novel Perspectives on Mucormycosis: Pathophysiology, Presentation, and Management". Clinical Microbiology Reviews. 18 (3): 556–69. doi:10.1128/CMR.18.3.556-569.2005. PMC 1195964. PMID 16020690.
- ^ Spellberg, Brad; Walsh, Thomas J.; Kontoyiannis, Dimitrios P.; Edwards, Jr.; Ibrahim, Ashraf S. (2009). "Recent Advances in the Management of Mucormycosis: From Bench to Bedside". Clinical Infectious Diseases. 48 (12): 1743–51. doi:10.1086/599105. PMC 2809216. PMID 19435437.
- ^ Grooters, A (2003). "Pythiosis, lagenidiosis, and zygomycosis in small animals". Veterinary Clinics of North America. Small Animal Practice. 33 (4): 695. doi:10.1016/S0195-5616(03)00034-2. PMID 12910739.
- ^ Ribes, J. A.; Vanover-Sams, C. L.; Baker, D. J. (2000). "Zygomycetes in Human Disease". Clinical Microbiology Reviews. 13 (2): 236–301. doi:10.1128/CMR.13.2.236-301.2000. PMC 100153. PMID 10756000.
- ^ Prabhu, R. M.; Patel, R. (2004). "Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment". Clinical Microbiology and Infection. 10: 31–47. doi:10.1111/j.1470-9465.2004.00843.x. PMID 14748801.
- ^ "Merck Veterinary Manual". Retrieved 2009-04-04.
- ^ Snyder, Katherine D.; Spaulding, Kathy; Edwards, John (2010). "Imaging diagnosis—tracheobronchial zygomycosis in a cat". Veterinary Radiology & Ultrasound. 51 (6): 617–20. doi:10.1111/j.1740-8261.2010.01720.x. PMID 21158233.
- ^ Joplin toll rises to 151; some suffer from fungus
|
Fungal infection and mesomycetozoea (B35–B49, 110–118)
|
|
Superficial and
cutaneous
(dermatomycosis):
Tinea = skin;
Piedra (exothrix/
endothrix) = hair |
| Ascomycota |
Dermatophyte
(Dermatophytosis) |
| By location |
- Tinea barbae/tinea capitis
- Tinea corporis
- Tinea cruris
- Tinea manuum
- Tinea pedis (athlete's foot)
- Tinea unguium/onychomycosis
- White superficial onychomycosis
- Distal subungual onychomycosis
- Proximal subungual onychomycosis
- Tinea corporis gladiatorum
- Tinea faciei
- Tinea imbricata
- Tinea incognito
- Favus
|
|
| By organism |
- Epidermophyton floccosum
- Microsporum canis
- Microsporum audouinii
- Trichophyton interdigitale/mentagrophytes
- Trichophyton tonsurans
- Trichophyton schoenleini
- Trichophyton rubrum
- Trichophyton verrucosum
|
|
|
| Other |
- Hortaea werneckii
- Piedraia hortae
|
|
|
| Basidiomycota |
- Malassezia furfur
- Tinea versicolor
- Pityrosporum folliculitis
- Trichosporon
|
|
|
Subcutaneous,
systemic,
and opportunistic |
| Ascomycota |
Dimorphic
(yeast+mold) |
| Onygenales |
- Coccidioides immitis/Coccidioides posadasii
- Coccidioidomycosis
- Disseminated coccidioidomycosis
- Primary cutaneous coccidioidomycosis. Primary pulmonary coccidioidomycosis
- Histoplasma capsulatum
- Histoplasmosis
- Primary cutaneous histoplasmosis
- Primary pulmonary histoplasmosis
- Progressive disseminated histoplasmosis
- Histoplasma duboisii
- Lacazia loboi
- Paracoccidioides brasiliensis
|
|
| Other |
- Blastomyces dermatitidis
- Blastomycosis
- North American blastomycosis
- South American blastomycosis
- Sporothrix schenckii
- Penicillium marneffei
|
|
|
| Yeast-like |
- Candida albicans
- Candidiasis
- Oral
- Esophageal
- Vulvovaginal
- Chronic mucocutaneous
- Antibiotic candidiasis
- Candidal intertrigo
- Candidal onychomycosis
- Candidal paronychia
- Candidid
- Diaper candidiasis
- Congenital cutaneous candidiasis
- Perianal candidiasis
- Systemic candidiasis
- Erosio interdigitalis blastomycetica
- C. glabrata
- C. tropicalis
- C. lusitaniae
- Pneumocystis jirovecii
- Pneumocystosis
- Pneumocystis pneumonia
|
|
| Mold-like |
- Aspergillus
- Aspergillosis
- Aspergilloma
- Allergic bronchopulmonary aspergillosis
- Primary cutaneous aspergillosis
- Exophiala jeanselmei
- Fonsecaea pedrosoi/Fonsecaea compacta/Phialophora verrucosa
- Geotrichum candidum
- Pseudallescheria boydii
|
|
|
| Basidiomycota |
- Cryptococcus neoformans
- Cryptococcosis
- Trichosporon spp
- Trichosporonosis
|
|
Zygomycota
(Zygomycosis) |
Mucorales
(Mucormycosis) |
- Rhizopus oryzae
- Mucor indicus
- Lichtheimia corymbifera
- Syncephalastrum racemosum
- Apophysomyces variabilis
|
|
Entomophthorales
(Entomophthoramycosis) |
- Basidiobolus ranarum
- Conidiobolus coronatus/Conidiobolus incongruus
|
|
|
Microsporidia
(Microsporidiosis) |
- Enterocytozoon bieneusi/Encephalitozoon intestinalis
|
|
|
| Mesomycetozoea |
|
|
| Ungrouped |
- Alternariosis
- Fungal folliculitis
- Fusarium
- Granuloma gluteale infantum
- Hyalohyphomycosis
- Otomycosis
- Phaeohyphomycosis
|
UpToDate Contents
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- 1. ムコール症（接合真菌症） mucormycosis zygomycosis
- 2. 真菌性副鼻腔炎 fungal rhinosinusitis
- 3. 肺移植後の真菌感染症 fungal infections following lung transplantation
- 4. 糖尿病患者の易感染性 susceptibility to infections in persons with diabetes mellitus
- 5. 新生児における特殊な真菌感染症 unusual fungal infections in the neonate
English Journal
- Emerging infectious diseases with cutaneous manifestations: Fungal, helminthic, protozoan and ectoparasitic infections.
- Kollipara R1, Peranteau AJ2, Nawas ZY3, Tong Y2, Woc-Colburn L4, Yan AC5, Lupi O6, Tyring SK7.
- Journal of the American Academy of Dermatology.J Am Acad Dermatol.2016 Jul;75(1):19-30. doi: 10.1016/j.jaad.2016.04.032.
- Given increased international travel, immigration, changing climate conditions, and the increased incidence of iatrogenic immunosuppression, fungal, protozoan, helminthic, and ectoparasitic infections that were once uncommon are being seeing more frequently in the Western hemisphere. However, the di
- PMID 27317513
- Breaking the Mold: A Review of Mucormycosis and Current Pharmacological Treatment Options.
- Riley TT1, Muzny CA2, Swiatlo E3, Legendre DP4.
- The Annals of pharmacotherapy.Ann Pharmacother.2016 Jun 15. pii: 1060028016655425. [Epub ahead of print]
- OBJECTIVE: To review the current literature for the pathogenesis of mucormycosis, discuss diagnostic strategies, and evaluate the efficacy of polyenes, triazoles, and echinocandins as pharmacological treatment options.DATA SOURCES: An electronic literature search was conducted in PubMed using the ME
- PMID 27307416
- Efficacy and safety of itraconazole use in infants.
- Chen S1, Sun KY1, Feng XW1, Ran X1, Lama J1, Ran YP2,3.
- World journal of pediatrics : WJP.World J Pediatr.2016 Jun 10. [Epub ahead of print]
- BACKGROUND: Itraconazole has been used to treat fungal infections, in particular invasive fungal infections in infants or neonates in many countries.DATA SOURCES: Literature search was conducted through Ovid EMBASE, PubMed, ISI Web of Science, CNKI and Google scholarship using the following key word
- PMID 27286691
Japanese Journal
- 急性リンパ性白血病寛解導入療法中に発症した播種性ムーコル症の一例
- かつて接合菌症と呼ばれたムーコル症等の診断と治療 (特集 呼吸器真菌感染症)
- Rice-Field Drowning-Associated Pneumonia in which Pseudomonas spp., Aspergillus fumigatus, and Cunninghamella sp. Are Isolated
Related Pictures
★リンクテーブル★
[★]
- 英
- mucormycosis
- 同
- 藻菌症 フィコミコーシス phycomycosis、接合菌症 zygomycosis
- 関
- ムコール科
- first aid step1 2006 p.257
病原体
病型
検査
- グロコット染色した病理標本からの菌糸の同定
- 血液培養：単離されることは少ない
治療
[★]
エントモフトラ症
- 関
- phycomycosis、zygomycosis
[★]
藻菌症
- 関
- entomophthoramycosis、zygomycosis
[★]
- 英
- zygomycosis
- 関
- 接合菌症