wheat germ agglutinin

コムギ胚芽凝集素

関

WGA

WordNet

1. a small apparently simple structure (as a fertilized egg) from which new tissue can develop into a complete organism
2. annual or biennial grass having erect flower spikes and light brown grains
3. grains of common wheat; sometimes cooked whole or cracked as cereal; usually ground into flour (同)wheat_berry
4. an antibody that causes agglutination of a specific antigen

PrepTutorEJDIC

1. 細菌,ばい菌 / (植物の)胚(はい),幼芽;(動物の)卵子 / 原因;(発達の)初期
2. 小麦
3. 凝集素(赤血球などの凝集反応を起こす抗体)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/02/01 11:29:36」(JST)

wiki en

[Wiki en表示]

Wheat germ agglutinin or WGA is a lectin that protects wheat (Triticum vulgaris) from insects, yeast and bacteria. An agglutinin protein, it binds to N-acetyl-D-glucosamine and Sialic acid. N-acetyl-D-glucosamine in the natural environment of wheat is found in the chitin of insects, and the cell membrane of yeast & bacteria. WGA is found abundantly—but not exclusively—in the wheat kernel, where it got the 'germ' name from. In mammals the N-acetyl-D-glucosamine that WGA binds to is found in cartilage and cornea among other places. In those animals sialic acid is found in mucous membranes, e.g. the lining of the inner nose, and digestive tract.

In solution, WGA exists mostly as a heterodimer of 38,000 daltons. It is cationic at physiological pH.

See also

• Proteopedia: 2uvo - High resolution crystal structure of Wheat Germ Agglutinin in complex with N-acetyl-D-glucosamine
• Proteopedia: 2uwg - Crystal structure of Wheat Germ Agglutinin isolectin 1 in complex with glycosylurethan

References

UpToDate Contents

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• 1. 食事または栄養補助食品による脂質低下 lipid lowering with diet or dietary supplements
• 2. ハーブ剤および栄養補助食品による肝毒性 hepatotoxicity due to herbal medications and dietary supplements
• 3. 自己免疫性溶血性貧血の病因：寒冷凝集素症 pathogenesis of autoimmune hemolytic anemia cold agglutinin disease
• 4. 自己免疫性溶血性貧血の病因：温暖凝集素と薬剤 pathogenesis of autoimmune hemolytic anemia warm agglutinins and drugs
• 5. 交差適合試験での不適合 the incompatible crossmatch

English Journal

• Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis.

• Ruffin M, Voland M, Marie S, Bonora M, Blanchard E, Blouquit-Laye S, Naline E, Puyo P, Le Rouzic P, Guillot L, Corvol H, Clement A, Tabary O.SourceInserm, U938, 34 Rue Crozatier, 75012 Paris, France; UPMC, University of Paris 06, 4 Place Jussieu, 75005 Paris, France.
• Biochimica et biophysica acta.Biochim Biophys Acta.2013 Dec;1832(12):2340-51. doi: 10.1016/j.bbadis.2013.09.012. Epub 2013 Sep 27.
• Cystic fibrosis (CF) airway epithelium is constantly subjected to injury events due to chronic infection and inflammation. Moreover, abnormalities in CF airway epithelium repair have been described and contribute to the lung function decline seen in CF patients. In the last past years, it has been p
• PMID 24080196

• In vivo digestion of bovine milk fat globules: effect of processing and interfacial structural changes. I. Gastric digestion.

• Gallier S, Cui J, Olson TD, Rutherfurd SM, Ye A, Moughan PJ, Singh H.SourceRiddet Institute, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. S.Gallier@massey.ac.nz
• Food chemistry.Food Chem.2013 Dec 1;141(3):3273-81. doi: 10.1016/j.foodchem.2013.06.020. Epub 2013 Jun 14.
• The aim was to study the in vivo gastric digestion of fat globules in bovine cream from raw, pasteurised or pasteurised and homogenised milk. Fasted rats were gavaged once and chyme samples were collected after 30, 120 and 180 min post-gavage. Proteins from raw (RC) and pasteurised (PC) creams appea
• PMID 23871087

• Traceless Labeling of Glycoproteins and Its Application to the Study of Glycoprotein-Protein Interactions.

• Yang YL, Lee YP, Yang YL, Lin PC.SourceDepartment of Chemistry, National Sun Yat-sen University , Kaohsiung 804, Taiwan.
• ACS chemical biology.ACS Chem Biol.2013 Nov 8. [Epub ahead of print]
• A new chemical method for the traceless labeling of glycoproteins with synthetic boronic acid (BA)-tosyl probes was successfully developed. The BA moiety acts as an affinity head to direct the formation of a cyclic boronate diester with the diol groups of glycans. Following this step, the electrophi
• PMID 24180370

Japanese Journal

• Serum alkaline phosphatase isoenzymes in laboratory beagle dogs detected by polyacrylamide-gel disk electrophoresis

• Hatayama Kazuhisa,Nishihara Yoshito,Kimura Sayaka [他],GOTO Ken,NAKAMURA Daichi,WAKITA Atsushi,URASOKO Yoshinaka
• Journal of toxicological sciences 36(5), 653-660, 2011-10-01
• … In order to identify the origin of each ALP isoenzyme, tissue ALP extracts from the liver, bone and small intestine and serum samples were treated with neuraminidase, anti-small intestinal ALP antibody, ALP inhibitor levamisole and/or wheat germ agglutinin (WGA). …
• NAID 10029481560

• A possible new relay for tongue thermal sense in the dorsal margin of the trigeminal principal nucleus in rats

• Hayama Tomio,Hashimoto Koji,ハヤマ トミオ,ハシモト ヒロシ,羽山 富雄,橋本 弘司,羽山 富雄
• Brain Research 1386, 100-108, 2011-04-22
• … Connections of the dorsal margin of the PV were neuroanatomically identified using wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) with electrophysiological techniques. …
• NAID 120003020784

Related Links

• Qdot,1次抗体標識/タンパク質標識：ライフテクノロジーズジャパン(Life ...

小麦胚芽レクチン（WGA : Wheat germ agglutinin）は、約36,000の分子量を持つ タンパク質であり、糖タンパクや糖脂質におけるN-アセチル ... Qdot® 655 Wheat Germ Agglutinin（WGA:小麦胚芽レクチン）を用いて、HeLa細胞を染色ラベルした画像. Qdot( R) ...

• Wheat germ agglutinin - Wikipedia, the free encyclopedia

Wheat germ agglutinin or WGA is a lectin that protects wheat (Triticum vulgaris) from insects, yeast and bacteria. An agglutinin protein, it binds to N-acetyl-D- glucosamine and Sialic acid. N-acetyl-D-glucosamine in the natural environment of ...

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★リンクテーブル★

リンク元	「WGA」「コムギ胚芽凝集素」
拡張検索	「wheat germ agglutinin-horseradish peroxidase conjugate」
関連記事	「germ」「wheat」「agglutinin」「wheat germ」

「WGA」

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• コムギ胚芽凝集素

関

wheat germ agglutinin

「コムギ胚芽凝集素」

　　[★]

英

wheat germ agglutinin、WGA

「wheat germ agglutinin-horseradish peroxidase conjugate」

　　[★]

小麦胚芽凝集素・西洋ワサビペルオキシダーゼ複合体

「germ」

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• n.

• 微生物、(発生)胚、胚芽、原基

関

anlage、anlagen、embryo、embryonic、germinal、microbe、microbial、microorganism、placode、primordia、primordium

　 　

「wheat」

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コムギ

関

durum wheat、Triticum、Triticum aestivum

　 　 　

「agglutinin」

　　[★]

• n.

• 凝集素、アグルチニン

　 　

「wheat germ」

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コムギ胚芽、麦芽

関

malt