WordNet

provide with water; "We watered the buffalo"
binary compound that occurs at room temperature as a clear colorless odorless tasteless liquid; freezes into ice below 0 degrees centigrade and boils above 100 degrees centigrade; widely used as a solvent (同)H2O
supply with water, as with channels or ditches or streams; "Water the fields" (同)irrigate
once thought to be one of four elements composing the universe (Empedocles)
secrete or form water, as tears or saliva; "My mouth watered at the prospect of a good dinner"; "His eyes watered"
a liquid necessary for the life of most animals and plants; "he asked for a drink of water"
fill with tears; "His eyes were watering"
relating to or resembling or consisting of water; "a watery substance"; "a watery color"
overly diluted; thin and insipid; "washy coffee"; "watery milk"; "weak tea" (同)washy, weak
filled with water; "watery soil"
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
abnormally low level of potassium in the circulating blood leading to weakness and heart abnormalities; associated with adrenal tumors or starvation or taking diuretics
frequent and watery bowel movements; can be a symptom of infection or food poisoning or colitis or a gastrointestinal tumor (同)diarrhoea, looseness of the bowels, looseness

PrepTutorEJDIC

〈U〉水 / 《しばしば複数形で》『海』(『湖,川』)『の水』 / 《複数形で》流れる水;(海・川・湖などの)波立つ水《+of+名》 / 《複数形で》(特定の)水域,領海,近海 / 〈U〉潮位,水位;《the water》水面 / 〈U〉分泌液(涙・汗・尿など) / 〈U〉溶液,…水 / 《複数形で》(飲用の)鉱泉水 / 〈U〉(織物・金属などの)波紋 / …‘に'『水をかける』(まく,やる) / 〈動物〉‘に'水を飲ませる / …‘に'水を供給する;…‘を'潅漑(かんがい)する / 〈液体など〉‘を'水で割る,薄める《+名+down,+down+名》 / 〈織物・金属など〉‘に'波紋(波模様)をつける / 〈動物などが〉水を飲む:〈船・機関などが〉給水を受ける / 〈目・口などが〉分泌液を出す
水の;水の関連した;水を含んだ / (色が)薄い,淡い / (食物などが)水っぽい / (目が)涙ぐんだ
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. VIP産生腫瘍：臨床的特徴、診断、およびマネージメントvipoma clinical manifestations diagnosis and management [show details]
…Verner-Morrison syndrome, and the watery diarrhea, hypokalemia, and hypochlorhydria or achlorhydria (WDHA) syndrome. VIPoma syndrome is characterized by watery diarrhea that persists with fasting. Stools …
2. 成人の顔面紅潮に対するアプローチapproach to flushing in adults [show details]
…inhibitory peptides, and pancreatic peptides . Typical presentation includes watery diarrhea, hypokalemia, and achlorhydria (WDHA syndrome) . Flushing occurs in 20 percent of patients and is attributable…
3. 血管作動性腸管ポリペプチドvasoactive intestinal polypeptide [show details]
…appreciably change with a meal. In pathologic conditions, like pancreatic cholera (watery diarrhea-hypokalemia-achlorhydria, WDHA, or Verner-Morrison syndrome ), VIP levels can be extraordinarily high . Although…
4. 成人における低カリウム血症の原因causes of hypokalemia in adults [show details]
… finding in hypokalemia, primarily because the major causes of hypokalemia (such as diuretics, vomiting, and hyperaldosteronism, described below) also lead to losses of hydrogen ions. Hypokalemia is an important …
5. 成人における低カリウム血症の臨床症状および治療clinical manifestations and treatment of hypokalemia in adults [show details]
…and treatment of hypokalemia will be reviewed here. The causes of and evaluation of patients with hypokalemia are discussed separately. The severity of the manifestations of hypokalemia tends to be proportionate …

English Journal

Poorly Differentiated Neuroendocrine Tumor of the Esophagus with Hypertrophic Osteoarthropathy and Brain Metastasis: A Success Story.

Saif MW, Vethody C.
Cureus. 2016 Jun;8(6)e646.
Neuroendocrine carcinomas (NECs) of the esophagus are very rare. The majority of the patients with NECs present with metastasis. Paraneoplastic syndromes, such as syndrome of inappropriate secretion of anti-diuretic hormone and watery diarrhea-hypokalemia-achlorhydria syndrome, have been reported in
PMID 27446766

Hypokalemic rhabdomyolysis due to watery diarrhea, hypokalemia, achlorhydria (WDHA) syndrome caused by vipoma.

Kibria R, Ahmed S, Ali SA, Barde CJ.
Southern medical journal. 2009 Jul;102(7)761-4.
Mild hypokalemia is common and encountered in a multitude of diseases, but severe hypokalemia leading to rhabdomyolysis is relatively rare. The watery diarrhea, hypokalemia, achlorhydria (WDHA) syndrome caused by vasoactive intestinal polypeptide (VIP)-producing tumors, is an extremely rare cause of
PMID 19488018

A Pancreatic Polypeptide-Producing Pancreatic Tumor Causing WDHA Syndrome.

Amrilleva V, Slater EP, Waldmann J, Bonorden D, Fendrich V.
Case reports in gastroenterology. 2008 Jul;2(2)238-43.
We report the case of a 46-year-old female patient with WDHA (watery diarrhea/hypokalemia/achlorhydria) syndrome caused by a pancreatic polypeptide-producing tumor in the head of the pancreas. Whereas VIP and other pancreatic endocrine hormones were in the normal range, only serum levels of pancreat
PMID 21490894

Japanese Journal

ソマトスタチンアナログ投与による全身状態安定化により，診断と治療が可能であった膵神経内分泌腫瘍，Vasoactive Intestinal Polypeptide（VIP）産生腫瘍の1例

河原聡一郎,重西邦浩,植木亨,堤康一郎,織田崇志,小林沙代,藤澤智雄,名和徹,貞森裕,大野京太郎
日本消化器病学会雑誌 117(1), 84-91, 2020
<p>症例は68歳女性．補液にて改善しない水様性下痢と腎不全にて当院転院．ICU管理にて腎機能改善後，造影CTを施行し，膵体部と肝に多血性の腫瘤を認めた．臨床症状と合わせてVIP産生腫瘍と考え，ソマトスタチンアナログを開始．すると下痢は著明に改善し全身状態も安定した．そこでEUS-FNAにて神経内分泌腫瘍と診断後，膵原発巣と肝転移巣の外科的切除を施行した．術後の病理にてVIP産生腫瘍と …
NAID 130007784877

Vasoactive intestinal polypeptide 産生膵腫瘍による大量下痢からの循環・腎機能不全に対し持続的血液濾過透析など生命補助下に腫瘍切除しえた1例

廣瀬哲朗,西村充孝,東大介,高橋則尋,山岡竜也,安田勝太郎,石川順英,嶋田俊秀,荻野哲朗,西平友彦
日本消化器外科学会雑誌 43(6), 640-646, 2010-06-01
症例は60歳の女性で,1年前より腸炎症状にて輸液治療をされており,低カリウム,脚力低下にても入院歴あり.本年になり糖尿病指摘.交通事故を契機の精査で膵臓に10cm大の腫瘍を指摘された.治療目的で近隣病院に入院中1日あたり5〜8回におよぶ下痢による腎不全となり当院へ転送,循環不全,高度アシドーシス,低カリウムに対し輸液管理,塩酸ロペラミド・酢酸オクトレオチド投与,透析・持続的血液濾過透析で生命維持を …
NAID 110007656696

褐色細胞腫・神経節腫混合腫瘍によるWDHA症候群の1例

石黒敦,平井裕一,長谷川範幸 [他],中村潤子,田村美智子,西村祥二,貝森光大,笹野公伸
日本内科学会雑誌 91(5), 1585-1588, 2002-05-10
… 性下痢,四肢脱力で近医受診.低K血症,右副腎腫瘍を認め当科紹介となった.血中vasoactive intestinal polypeptide (VIP),血中・尿中カテコラミンおよびその代謝産物の高値を認めwatery diarrhea-hypokalemia-achlorhydria (WDHA)症候群を呈した褐色細胞腫と診断.腫瘍摘出術後,臨床症状,各種検査値の改善が得られた.病理組織像より,褐色細胞腫・神経節腫混合腫瘍でVIP分泌は神経節腫部 …
NAID 10008695666