WordNet

material of a particular kind or constitution; "the immune response recognizes invading substances"
a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
the real physical matter of which a person or thing consists; "DNA is the substance of our genes"
any agent that produces vasoconstriction and a rise in blood pressure (usually understood as increased arterial pressure)

PrepTutorEJDIC

〈U〉『物質』,物 / 〈U〉《the~》(…の)『趣旨』,本音《+of+名》 / 〈U〉(スープなどの)濃さ,こく,中身[の詰まっていること] / 〈U〉『実質』,実 / 〈U〉《古》財産,資産

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Olcegepant blocks neurogenic and non-neurogenic CGRPergic vasodepressor responses and facilitates noradrenergic vasopressor responses in pithed rats.

Avilés-Rosas VH1, Rivera-Mancilla E1, Marichal-Cancino BA1, Manrique-Maldonado G1, Altamirano-Espinoza AH1, Maassen Van Den Brink A2, Villalón CM1.
British journal of pharmacology.Br J Pharmacol.2017 Jul;174(13):2001-2014. doi: 10.1111/bph.13799. Epub 2017 May 2.
PMID 28369749

Environmental concentrations of cocaine and its main metabolites modulated antioxidant response and caused cyto-genotoxic effects in zebrafish embryo cells.

Parolini M1, Ghilardi A2, Della Torre C2, Magni S2, Prosperi L2, Calvagno M2, Del Giacco L2, Binelli A2.
Environmental pollution (Barking, Essex : 1987).Environ Pollut.2017 Jul;226:504-514. doi: 10.1016/j.envpol.2017.04.046. Epub 2017 Apr 24.
PMID 28449966

Precise simultaneous quantification of methadone and cocaine in rat serum and brain tissue samples following their successive i.p. administration.

Nakhla DS1, Hussein LA2, Magdy N2, Abdallah IA3, Hassan HE4.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2017 Mar 24;1048:19-29. doi: 10.1016/j.jchromb.2017.01.048. Epub 2017 Feb 7.
PMID 28192759

Evidence for a Digitalis-Like Substance in the Hypothalamopituitary Axis in Rats : Implications in the Central Cardiovascular Regulation Associated with an Excess Intake of Sodium

TAKAHASHI HAKUO,MATSUZAWA MAKOTO,OKABAYASHI HIDEOKI,SUGA KEISUKE,IKEGAKI IWAO,YOSHIMURA MANABU,IJICHI HAMAO,OKAMURA HITOSHI,MURAKAMI SADATSUGU,IBATA YASUHIKO
Japanese circulation journal 51(10), 1199-1207, 1987-10-20
… The origin and the physiological role of an endogenous digitalis-like substance were investigated by measuring both the digoxin-like substance by a digoxin radioimmunoassay (RIA) and the inhibitory activity on the ouabain sensitive Na^+, K^+-ATPase in rats. … The digitalis-like substance was in high concentration in the pituitary, and in decreasing concentration in the hypothalamus, adrenal and the other organs as measured by RIA using an antibody raised from a goat. …
NAID 110002583814

吉村寿博
日本産科婦人科學會雜誌 37(2), 271-276, 1985-02-01
ヒト血漿を37℃で長時間incubationすると,activepressorprinciple(APP)とよばれるheatstableな昇圧物質が生じてくる事が知られている.節遮断薬投与下の麻酔ラットの観血的な頚動脈圧測定法を用いたbioassayにより,APPの生化学的性状と,妊娠高血圧患者における意義とを検討した.1)Incubationした血漿より,APPは,chloroform:meth …
NAID 110002115104

布谷隆之,松浦俊平,玉井恒夫,龍見信哉,佐川典正,森崇栄
日本産科婦人科學會雜誌 37(1), 15-23, 1985-01-01
妊娠個体の子宮血流量維持は胎児育成にとって重要な意義をもつがangiotensin？(A？)投与に対しては血流量の増加を招くのに対しnorepinephrine(NE)投与には逆に減少を示すことが知られている.これらの妊娠時子宮血行動態の特性,とくにNEに対する反応性亢進が血管壁自体の反応性変化にもとづくものであるかにつき検討する目的で妊娠末期および経産非妊ブタの子宮動脈,腸間膜動脈,大動脈条片を …
NAID 110002190464