uracil-DNA glycosidase

ウラシルDNAグリコシダーゼ

WordNet

1. the 4th letter of the Roman alphabet (同)d
2. a base containing nitrogen that is found in RNA (but not in DNA) and derived from pyrimidine; pairs with adenine (同)U

PrepTutorEJDIC

1. deuteriumの化学記号
2. ウラシル(核酸の加水分解で得られる針状結晶)
3. deoxyribonucleic acidディオキシリボ核酸

UpToDate Contents

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• 1. 分子遺伝学の原理 principles of molecular genetics
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English Journal

• Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

• Komor AC1,2, Kim YB1,2, Packer MS1,2, Zuris JA1,2, Liu DR1,2.
• Nature.Nature.2016 Apr 20;533(7603):420-4. doi: 10.1038/nature17946.
• Current genome-editing technologies introduce double-stranded (ds) DNA breaks at a target locus as the first step to gene correction. Although most genetic diseases arise from point mutations, current approaches to point mutation correction are inefficient and typically induce an abundance of random
• PMID 27096365

• Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination.

• Bregenhorn S1, Kallenberger L2, Artola-Borán M2, Peña-Diaz J3, Jiricny J4.
• Nucleic acids research.Nucleic Acids Res.2016 Apr 7;44(6):2691-705. doi: 10.1093/nar/gkv1535. Epub 2016 Jan 6.
• During class switch recombination (CSR), antigen-stimulated B-cells rearrange their immunoglobulin constant heavy chain (CH) loci to generate antibodies with different effector functions. CSR is initiated by activation-induced deaminase (AID), which converts cytosines in switch (S) regions, repetiti
• PMID 26743004

• Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated Lesions.

• Chen Z1, Eder MD2, Elos MT2, Viboolsittiseri SS2, Chen X2, Wang JH3.
• Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Mar 1;196(5):2335-47. doi: 10.4049/jimmunol.1502184. Epub 2016 Jan 25.
• Activation-induced deaminase (AID) functions by deaminating cytosines and causing U:G mismatches, a rate-limiting step of Ab gene diversification. However, precise mechanisms regulating AID deamination frequency remain incompletely understood. Moreover, it is not known whether different sequence con
• PMID 26810227

Related Links

• uracil-DNA glycosidase - Definition - Mondofacto

uracil-DNA glycosidase definition from the mondofacto online medical dictionary ... Search dictionary help uracil-DNA glycosidase medical dictionary <enzyme> <cell biology> Catalyses hydrolysis of n-glycosidic bond of damaged nucleotide ...

• What does uracil-dna glycosidase mean?

Definition of uracil-dna glycosidase in the Definitions.net dictionary. Meaning of uracil-dna glycosidase. What does uracil-dna glycosidase mean? Information and translations of uracil-dna glycosidase in the most comprehensive ...

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★リンクテーブル★

リンク元	「ウラシル-DNAグリコシダーゼ」「ウラシルDNAグリコシダーゼ」
関連記事	「D」「DNA」「glycosidase」「uracil」

「ウラシル-DNAグリコシダーゼ」

　　[★]

英

uracil-DNA glycosidase

同

ウラシル-DNAグリコシラーゼ

「ウラシルDNAグリコシダーゼ」

　　[★]

英

uracil-DNA glycosidase

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA

　

「glycosidase」

　　[★]

グリコシダーゼ

関

endoglycosidase、exoglycosidase、glycoside hydrolase

「uracil」

　　[★] ウラシル, U, Ura