- 関
- anti-tumor activity、antitumor activity、antitumor efficacy
WordNet
- to put down by force or authority; "suppress a nascent uprising"; "stamp down on littering"; "conquer ones desires" (同)stamp down, inhibit, subdue, conquer, curb
- reduce the incidence or severity of or stop; "suppress a yawn"; "this drug can suppress the hemorrhage"
- put out of ones consciousness (同)repress
- an electrical device for suppressing unwanted currents (同)suppresser
- someone who suppresses; "dictators are suppressors of free speech" (同)suppresser
- a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene) (同)suppresser, suppressor_gene, suppresser gene
- any specific behavior; "they avoided all recreational activity"
- (chemistry) the capacity of a substance to take part in a chemical reaction; "catalytic activity"
- an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
PrepTutorEJDIC
- 〈反乱など〉‘を'『鎮圧する』…,‘の'活動を押える / 〈感情・欲望など〉‘を'『抑制する』,抑える / …‘の'発表を禁止する,伏せる
- 抑圧する人,鎮圧者 / (ラジオ・テレビの)妨害電波(混信)防止装置
- 〈U〉『活動』,働き;活力 / 《しばしば複数形で》(種々の)『活動』,行事;(学生の)学内(外)活動,クラブ活動 / 〈U〉(商況・市場などの)活発,活気
UpToDate Contents
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English Journal
- Non-cell autonomous or secretory tumor suppression.
- Chua CE1, Chan SN, Tang BL.
- Journal of cellular physiology.J Cell Physiol.2014 Oct;229(10):1346-52. doi: 10.1002/jcp.24574.
- Many malignancies result from deletions or loss-of-function mutations in one or more tumor suppressor genes, the products of which curb unrestrained growth or induce cell death in those with dysregulated proliferative capacities. Most tumor suppressors act in a cell autonomous manner, and only very
- PMID 24752809
- Phosphorylation-Regulated Degradation of the Tumor-Suppressor Form of PED by Chaperone-Mediated Autophagy in Lung Cancer Cells.
- Quintavalle C1, Di Costanzo S, Zanca C, Tasset I, Fraldi A, Incoronato M, Mirabelli P, Monti M, Ballabio A, Pucci P, Cuervo AM, Condorelli G.
- Journal of cellular physiology.J Cell Physiol.2014 Oct;229(10):1359-68. doi: 10.1002/jcp.24569.
- PED/PEA-15 is a death effector domain (DED) family member with a variety of effects on cell growth and metabolism. To get further insight into the role of PED in cancer, we aimed to find new PED interactors. Using tandem affinity purification, we identified HSC70 (Heat Shock Cognate Protein of 70
- PMID 24477641
- Alternative promoter activation leads to the expression of a novel human lysyl oxidase variant that functions as an amine oxidase.
- Kim S, Park S, Kim Y.
- International journal of molecular medicine.Int J Mol Med.2014 Sep;34(3):894-9. doi: 10.3892/ijmm.2014.1845. Epub 2014 Jul 10.
- The lysyl oxidase (LOX) family is an emerging family of amine oxidases that is responsible for lysine-mediated crosslinks found in collagen and elastin. Several novel functions, such as tumor suppression, tumor progression, cellular senescence, chemotaxis and the modification of histones have recent
- PMID 25017124
Japanese Journal
- 原 博志,長谷部 晃,佐伯 歩,阿部 亜美,山崎 裕,柴田 健一郎
- 北海道歯学雑誌 35(1), 16-24, 2014-09
- … We have found that the microbial lipopeptide FSL-1, a Toll-like receptor 2( TLR2) ligand, has the TLR2-mediated anti-tumor activity in vivo. … Therefore, we tested the anti-tumor activity in vivo of oral streptococci, because they are known to be recognized by TLR2. …
- NAID 120005476137
- dsRNAによるTAM,MDSCの腫瘍免疫抑制作用から活性化作用への変換 (特集 抗腫瘍免疫の抑制と活性化)
- microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
- Mitamura Takashi,Watari Hidemichi,Wang Lei,Kanno Hiromi,Kitagawa Makiko,Hassan Mohamed Kamel,Kimura Taichi,Tanino Mishie,Nishihara Hiroshi,Tanaka Shinya,Sakuragi Noriaki
- Molecular Cancer 13, 97, 2014-04-29
- … Results: The overexpression of MIR31 significantly promoted anchorage-independent growth in vitro and significantly increased the tumor forming potential in vivo. … MIR31 significantly suppressed the luciferase activity of mRNA combined with the LATS2 3'-UTR and consequently promoted the translocation of YAP1, a key molecule in the Hippo pathway, into the nucleus. …
- NAID 120005464724
Related Links
- 1. Oncogene. 2002 Jun 27;21(28):4351-62. The tumor suppressor activity of SOCS-1. Rottapel R, Ilangumaran S, Neale C, La Rose J, Ho JM, Nguyen MH, Barber D, Dubreuil P, de Sepulveda P. Department of Immunology, University ...
- Summary of "The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells." Histidine triad nucleotide-binding protein 1 (HINT1) is a haploinsufficient tumor suppressor gene that inhibits the Wnt/β ...
Related Pictures
★リンクテーブル★
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- 関
- anti-tumor activity、anti-tumor effect、antitumor action、antitumor efficacy、tumor suppressor activity
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- 関
- anti-tumor effect、antitumor action、antitumor activity、antitumor efficacy、tumor suppressor activity
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- 英
- antitumor activity、antitumor efficacy、tumor suppressor activity、anti-tumor activity
- 関
- 抗腫瘍作用、抗腫瘍効率
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- 関
- anti-tumor activity、antitumor activity、tumor suppressor activity
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- 関
- abrogate、abrogation、arrest、curb、depress、depression、inhibit、inhibition、restrain、restraint、subdue、suppression
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- 関
- inhibitory factor、repressor
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- 関
- active
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