WordNet
- a substance that exerts some force or effect
- a businessman who buys or sells for another in exchange for a commission (同)factor, broker
- any agent or representative of a federal agency or bureau (同)federal agent
- a representative who acts on behalf of other persons or organizations
- an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
- how long something has existed; "it was replaced because of its age"
- a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
- begin to seem older; get older; "The death of his wife caused him to age fast"
- make older; "The death of his child aged him tremendously"
PrepTutorEJDIC
- 『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
- 〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/28 06:19:42」(JST)
[Wiki en表示]
A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites.[1]
Examples include:[2]
- benzonidazole
- blasticidin S
- DAPI
- diminazene
- diminazene aceturate
- eflornithine
- ethidium
- isometamidium chloride
- lonidamine
- melaminylthioarsenate
- melarsoprol
- nifurtimox
- pentamidine
- posaconazole
- puromycin
- quinapyramine
- salicylhydroxamic acid
- suramin
- tetraphenylporphine sulfonate
See also[edit]
References[edit]
- ^ Trypanocidal Agents at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ MeSH list of agents 82014344
Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
|
|
Alveo-
late |
Apicom-
plexa |
Conoidasida/
(Coccidiostats) |
Cryptosporidiosis |
|
|
Isosporiasis |
- trimethoprim/sulfamethoxazole#
|
|
Toxoplasmosis |
- pyrimethamine
- sulfadiazine
|
|
|
Aconoidasida |
Malaria |
Individual
agents |
Hemozoin
inhibitors |
aminoquinolines |
- (4-): amodiaquine#
- chloroquine#
- (8-): primaquine#
- pamaquine
|
|
4-methanolquinolines |
- mefloquine#
- quinine#
- quinidine
|
|
Other |
|
|
|
Antifolates |
DHFR inhibitors
(antifols) |
- proguanil#
- chlorproguanil
|
|
Sulfonamides |
- sulfadoxine
- sulfamethoxypyrazine
|
|
Coformulation |
- sulfadoxine/pyrimethamine (SP)#
|
|
|
Sesquiterpene
lactones |
- artemether#
- artesunate#
- dihydroartemisinin
- artemotil
- artemisinin
|
|
Other |
- atovaquone (with proguanil as Malarone)
- tetracycline
- doxycycline#
- clindamycin
- pyronaridine
- piperaquine
|
|
|
Combi-
nations |
Fixed-dose (coformulated) ACTs |
- artemether/lumefantrine#
- artesunate/amodiaquine (ASAQ)
- artesunate/mefloquine (ASMQ)
- dihydroartemisinin/piperaquine
- artesunate/pyronaridine
|
|
Other combinations
(not co-formulated) |
- artesunate/SP
- artesunate/mefloquine
- quinine/tetracycline
- quinine/doxycycline
- quinine/clindamycin
|
|
|
|
Babesiosis |
|
|
|
|
Cilio-
phora |
- Balantidiasis: Tetracycline
|
|
|
Hetero-
kont |
- Blastocystosis: Metronidazole
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase.
- Olmo F1, Urbanová K1, Rosales MJ1, Martín-Escolano R1, Sánchez-Moreno M1, Marín C1.
- International journal for parasitology. Drugs and drug resistance.Int J Parasitol Drugs Drug Resist.2015 Jun 20;5(3):110-6. doi: 10.1016/j.ijpddr.2015.05.002. eCollection 2015.
- In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li
- PMID 26236582
- Synthesis and anti-Trypanosoma cruzi activity of new 3-phenylthio-nor-β-lapachone derivatives.
- Cardoso MF1, Salomão K2, Bombaça AC2, da Rocha DR1, da Silva Fde C1, Cavaleiro JA3, de Castro SL2, Ferreira VF4.
- Bioorganic & medicinal chemistry.Bioorg Med Chem.2015 Aug 1;23(15):4763-8. doi: 10.1016/j.bmc.2015.05.039. Epub 2015 Jun 12.
- We report herein a straightforward and efficient one-step reaction to prepare new nor-β-lapachone derivatives tethered with phenylthio groups at position 3 of the furan ring. We have screened the compounds on bloodstream trypomastigotes of Trypanosoma cruzi, the causative agent of Chagas disease, a
- PMID 26118339
- Unravelling the role of SNM1 in the DNA repair system of Trypanosoma brucei.
- Sullivan JA1, Tong JL1, Wong M1, Kumar A1, Sarkar H1, Ali S1, Hussein I1, Zaman I1, Meredith EL1, Helsby NA2, Hu L3, Wilkinson SR1.
- Molecular microbiology.Mol Microbiol.2015 May;96(4):827-38. doi: 10.1111/mmi.12973. Epub 2015 Mar 21.
- All living cells are subject to agents that promote DNA damage. A particularly lethal lesion are interstrand cross-links (ICL), a property exploited by several anti-cancer chemotherapies. In yeast and humans, an enzyme that plays a key role in repairing such damage are the PSO2/SNM1 nucleases. Here,
- PMID 25689597
Japanese Journal
- Enhanced Production of the Fluorinated Nucleoside Antibiotic Nucleocidin by a rif^R-Resistant Mutant of Streptomyces calvus IFO13200
- Natural Chromenes and Chromene Derivatives as Potential Anti-trypanosomal Agents(Pharmacognosy)
- Trypanocidal Activity of Triterpenes from Arrabidaea triplinervia and Derivatives(Pharmacognosy)
Related Links
- 英語をクリック → Trypanocidal Agent との組み合わせでEntrez を検索 メラルソプロール (Melarsoprol); ペンタミジン (Pentamidine); ヒ素剤 (Arsenical); エフロールニチン (Eflornithine); アデノシン (Adenosine); ポリアミン (Polyamine); (); ...
- A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites. Examples include: benzonidazole blasticidin S DAPI diminazene diminazene aceturate eflornithine ethidium isometamidium chloride lonidamine ...
★リンクテーブル★
[★]
- 代行者、代理人。代理業者
- 政府職員、官吏
- ある後位をする人、ある作用をするもの。動員、動力因、作用因。(文法)動作主。科学的変化を起こさせるもの、薬品、~剤。病原体
- 関
- agonist、agonistic、attorney、delegate、drug、etiologic agent、fomes、fomites、mediator、pathogen、pathogenic、pharmaceutical preparation、vector、vehicle
[★]
- 関
- aged、ageing、aging、year old