トロピン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/27 19:34:51」(JST)
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Tropine
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| Names |
| IUPAC name
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol
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| Other names
α-Tropine; Tropanol
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| Identifiers |
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CAS Number
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120-29-6 Y |
| ChemSpider |
10180559 N |
| Jmol interactive 3D |
Image |
| MeSH |
Tropine |
| PubChem |
8424 |
| UNII |
7YXR19M72Y Y |
InChI
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InChI=1S/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8+ N
Key: CYHOMWAPJJPNMW-JIGDXULJSA-N N
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InChI=1/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8+
Key: CYHOMWAPJJPNMW-JIGDXULJBD
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SMILES
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CN1[C@@H]2CC[C@H]1C[C@H](C2)O
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| Properties |
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Chemical formula
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C8H15NO |
| Molar mass |
141.21 g·mol−1 |
| Appearance |
Hygroscopic plates |
| Density |
1.016 g/cm3 at 100 °C |
| Melting point |
64 °C (147 °F; 337 K) |
| Boiling point |
233 °C (451 °F; 506 K) |
| Solubility |
Very soluble in water, diethyl ether, ethanol[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| N verify (what is YN ?) |
| Infobox references |
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Tropine is a derivative of tropane containing a hydroxyl group at third carbon. It is also called 3-tropanol.
Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
See also
References
- ^ Lide, David R. (1998), Handbook of Chemistry and Physics (87 ed.), Boca Raton, FL: CRC Press, pp. 3–564, ISBN 0-8493-0594-2
External links
- General reactions of tropine
English Journal
- Degradation of tropane alkaloids in baked bread samples contaminated with Solanaceae seeds.
- Marín-Sáez J, Romero-González R, Garrido Frenich A.
- Food research international (Ottawa, Ont.). 2019 Aug;122()585-592.
- Solanaceae plant seeds, which contain high concentrations of tropane alkaloids, have not been studied in real conditions of proofing and baking processes. In this work both lab vial trials and buckwheat and millet flour samples, contaminated with two species of Solanaceae plants, Datura stramonium a
- PMID 31229117
- Effect of tea making and boiling processes on the degradation of tropane alkaloids in tea and pasta samples contaminated with Solanaceae seeds and coca leaf.
- Marín-Sáez J, Romero-González R, Garrido Frenich A.
- Food chemistry. 2019 Jul;287()265-272.
- In this study, the degradation of tropane alkaloids in pasta under boiling (100 °C during 10 min) and tea making (100 °C and let cool 5 min) conditions has been evaluated for the first time. Pasta and green tea were contaminated with Datura Stramonium and Brugmansia Arborea seeds (pasta an
- PMID 30857698
- A Nickel(II) Nitrite Based Molecular Perovskite Ferroelectric.
- Xiong YA, Sha TT, Pan Q, Song XJ, Miao SR, Jing ZY, Feng ZJ, You YM, Xiong RG.
- Angewandte Chemie (International ed. in English). 2019 Jun;58(26)8857-8861.
- The X-site ion in organic-inorganic hybrid ABX perovskites (OHPs) varies from halide ion to bridging linkers like HCOO , N , NO , and CN . However, no nitrite-based OHP ferroelectrics have been reported so far. Now, based on non-ferroelectric [(CH ) N][Ni(NO ) ], through the combined methodologies o
- PMID 31050113
Japanese Journal
- Five New Nortropane Alkaloids and Six New Amino Acids from the Fruit of Morus alba LINNE Growing in Turkey
- Kusano Genjirou,Orihara Shiho,Tsukamoto Daisuke [他],SHIBANO Makio,COSKUN Maksut,GUNENC Aysegul,ERDURAK Ceyda Sibel
- Chemical & pharmaceutical bulletin 50(2), 185-192, 2002-02-01
- … Investigation of the constituents of the fruits of Morus alba LINNE(Moraceae)afforded five new nortropane alkaloids(1-5)along with nor-ψ-tropine(6)and six new amino acids, morusimic acids A-F(7-12). …
- NAID 110003616096
- Structures and Expression Patterns of Two Tropinone Reductase Genes from Hyoscyamus niger
- Nakajima Keiji,Oshita Yoko,Kaya Masahiko [他],YAMADA Yasuyuki,HASHIMOTO Takashi
- Bioscience, biotechnology, and biochemistry 63(10), 1756-1764, 1999-10-23
- … In the biosynthesis of tropane alkaloids, two tropinone reductases (TRs) catalyze reduction of tropinone to different stereoisomers, tropine and pseudotropine. …
- NAID 110002691996
- Effect of Tropine Derivatives, Antimuscarinic Agents, on the Growth of Bombyx mori Larvae
- Toyomura Nozomu,Kuwano Eiichi
- Bioscience, biotechnology, and biochemistry 62(10), 2046-2048, 1998-10-23
- A number of atropine analogs were synthesized and their effects on larval growth of the silkworm, Bombyx mori, were investigated by both topical application and dietary administration. Among the teste …
- NAID 110002679072
Related Links
- + Add to Word List Create new word list More... Word List Title: 3 to 50 characters max. Word List Description: 3 to 250 characters max. Public Private Definitions tropine [trō′pēn′, -pin] noun a poisonous, colorless heterocyclic ...
- Tropine definition, a white, crystalline, hygroscopic, water-soluble, poisonous alkaloid, C 8 H 15 NO, obtained chiefly by the hydrolysis of atropine or hyoscyamine. See more. Thesaurus Translator Reference Word of the Day Blog ...
★リンクテーブル★
[★]
- 英
- tropine
[★]
メチルオクタトロピン
- 関
- methyloctatropine bromide
[★]
アヘンアルカロイド・アトロピン合剤
[★]
複方オキシコドン・アトロピン合剤