トレ・ネーマ感染症、トレ・ネーマ感染
- 関
- bejel
WordNet
- (medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
- (phonetics) the alteration of a speech sound under the influence of a neighboring sound
- the pathological state resulting from the invasion of the body by pathogenic microorganisms
- (international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
- moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
- an incident in which an infectious disease is transmitted (同)contagion, transmission
- spirochete that causes disease in humans (e.g. syphilis and yaws)
PrepTutorEJDIC
- 〈U〉(病気の)伝染;感染 / 〈C〉伝染病
UpToDate Contents
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- 1. 梅毒の診断的検査 diagnostic testing for syphilis
- 2. 後期梅毒の病因、臨床症状、および治療 pathogenesis clinical manifestations and treatment of late syphilis
- 3. イールズ病 eales disease
- 4. 神経梅毒 neurosyphilis
- 5. 梅毒治療を受けている患者の臨床検査モニタリング laboratory monitoring of patients undergoing treatment for syphilis
English Journal
- Syphilis and HIV Co-Infection in Patients Who Attend an AIDS Outpatient Clinic in Vitoria, Brazil.
- Callegari FM, Pinto-Neto LF, Medeiros CJ, Scopel CB, Page K, Miranda AE.Author information Núcleo de Doenças Infecciosas, Universidade Federal do Espirito Santo, Av. Marechal Campos, 1468, Vitoria, ES, 29040-091, Brazil.AbstractOur goal was to determine the prevalence of, and risk factors associated with, syphilis in HIV-infected patients who attend an AIDS outpatient clinic in Vitoria, Brazil. We conducted a cross-sectional study-including interviews for demographic, behavioral, and clinical characteristics-and blood collection (venipuncture and fingerstick) for VDRL and treponemal tests (rapid test) in a total of 438 patients. The mean age was 43.0 years (SD = 11), and mean years of school was 8.1 (SD = 4.2). The prevalence of syphilis was 5.3 % (95 % CI 3.3-7.3). The treponemal test was positive in 18.9 % of participants. In multivariate analysis, prevalent syphilis infection was independently associated with male gender (AOR 4.6, 95 % CI 1.1-20.0), a history of male-male sex (AOR 1.8, 95 % CI 1.6-4.1), current use of antiretroviral therapy (AOR 5.5, 95 % CI 1.7-16.7), and history of treated syphilis infection (AOR 5.5, 95 % CI 2.0-15.8). Syphilis prevalence was high in patients living with HIV/AIDS who attend an AIDS clinic; therefore, routine sexually transmitted infections counseling and screening should be included in their care.
- AIDS and behavior.AIDS Behav.2014 Jan;18 Suppl 1:104-9. doi: 10.1007/s10461-013-0533-x.
- Our goal was to determine the prevalence of, and risk factors associated with, syphilis in HIV-infected patients who attend an AIDS outpatient clinic in Vitoria, Brazil. We conducted a cross-sectional study-including interviews for demographic, behavioral, and clinical characteristics-and blood coll
- PMID 23732958
- Use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening enzyme immunoassay results for the serological diagnosis of syphilis.
- Lam T, Lau H, Lee Y, Fung S, Leung W, Kam K.Author information Microbiology Division, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, Hong Kong.AbstractWe studied the use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening results of the Murex ICE Syphilis enzyme immunoassay (EIA) with the confirmatory results of both the Serodia Treponema pallidum particle agglutination (TPPA) and the fluorescent treponemal antibody-absorption (FTA-Abs) assays, for the serological diagnosis of syphilis. This was an observational study on the serum samples received by the Syphilis Laboratory, Hong Kong, during the period from January 2006 to December 2012. A total of 801 serum samples with discordant positive screening EIA results were used. Consensus results of such serum samples were derived from results of the EIA, TPPA and FTA-abs assays. The age range of the individuals was 14 to 104 years (median of 52). There were 369 males and 432 females. Of 378 serum samples, 139 showed agreement among positive results, 23 of 310 showed agreement among indeterminate results and 277 of 465 showed agreement among negative results. The proportions of agreement among positive, indeterminate and negative results were 0.37 (95% CI 0.32-0.42), 0.07 (95% CI 0.05-0.11) and 0.60 (95% CI 0.55-0.64), respectively; kappa 0.55 (95% CI 0.49-0.60). There were 60 serum samples with positive consensus results but negative INNO-LIA syphilis score results and 10 with negative consensus results but positive INNO-LIA syphilis score results. Although the INNO-LIA syphilis score assay can be considered a valid alternative confirmatory test for the serological diagnosis of syphilis, the present study showed that its use in the resolution of discordant positive screening EIA results was moderate. A more extensive characterization of serum samples with discordant reactive screening treponemal test results is necessary.
- International journal of STD & AIDS.Int J STD AIDS.2014 Jan;25(1):52-6. doi: 10.1177/0956462413491938. Epub 2013 Jul 19.
- We studied the use of the INNO-LIA syphilis score assay in the resolution of discordant positive screening results of the Murex ICE Syphilis enzyme immunoassay (EIA) with the confirmatory results of both the Serodia Treponema pallidum particle agglutination (TPPA) and the fluorescent treponemal anti
- PMID 23970631
- Europium nanoparticle-based high performing immunoassay for the screening of treponemal antibodies.
- Talha SM1, Hytönen J2, Westhorpe A3, Kumar S4, Khanna N4, Pettersson K1.Author information 1Department of Biotechnology, University of Turku, Turku, Finland.2Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland.3University of Surrey, Guildford, Surrey, United Kingdom.4Recombinant Gene Products Group, International Centre for Genetic Engineering & Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.AbstractTreponema pallidum subspecies pallidum (Tp) is the causative agent of syphilis which mainly spreads through sexual contact, blood transfusion and perinatal route. In order to curtail the spread of the infection and to clinically manage the disease, timely, accurate and reliable diagnosis is very important. We have developed an immunoassay for the detection of treponemal antibodies in human serum or plasma samples. In vivo biotinylated and non-biotinylated versions of the recombinant antigen were designed by the fusion of three Tp-specific antigens namely Tp15, Tp17 and Tp47. These fusion antigens were expressed in E. coli and purified using single-step metal affinity chromatography. Biotinylated fusion antigen immobilized on streptavidin coated plate was used to capture the treponemal antibodies and the non-biotinylated antigen coated on europium nanoparticles was used as tracer. Assays with two different incubation times of 10 min and 1 h were developed, and following the incubation the europium fluorescence was measured using time-resolved fluorometry. The developed time-resolved fluorometric (TRF) immunoassays were evaluated with in-house and commercial serum/plasma sample panels. For well-established treponemal antibodies positive or negative samples, the sensitivity of TRF immunoassay with 10 min incubation time was 97.4%, and of TRF immunoassay with 1 h incubation time was 98.7%, and the specificities of both the TRF immunoassays were 99.2%. For the samples with discordant results with the reference assays, both the TRF immunoassays showed better specificity than the Enzygnost syphilis enzyme immunoassay as a screening test. The two different incubation times did not have any significant effect on the signal to cutoff (S/Co) ratios obtained with the two immunoassays (p = 0.06). Our results indicate that the developed immunoassay with a short incubation time of 10 min has the potential to be used in clinical laboratories and in blood-bank settings as a screening test for treponemal antibodies.
- PloS one.PLoS One.2013 Dec 26;8(12):e84050. doi: 10.1371/journal.pone.0084050.
- Treponema pallidum subspecies pallidum (Tp) is the causative agent of syphilis which mainly spreads through sexual contact, blood transfusion and perinatal route. In order to curtail the spread of the infection and to clinically manage the disease, timely, accurate and reliable diagnosis is very imp
- PMID 24386329
Japanese Journal
- Skeletal Evidence of Probable Treponemal Infection in Free-ranging African Apes
- LOVELL NANCY C.,JURMAIN ROBERT,KILGORE LYNN
- Primates : journal of primatology 41(3), 275-290, 2000-07-31
- NAID 10014129887
- Cerebral Gumma Mimicking Glioblastoma on Magnetic Resonance Images : Case Report
- 上村 和也,YAMADA Takashi,TSUKADA Atsuro,ENOMOTO Takao,YOSHII Yoshihiko,NOSE Tadao
- Neurologia medico-chirurgica 35(7), 462-466, 1995-07-15
- 症例は39歳の女性。視野障害を主訴に入院した。MRI上右中大脳動脈近傍にT1強調像で直径約1cmのリング状増強効果を伴う腫瘍陰影を認め、周囲はT2強調像で高信号域を示した。神経膠芽腫を疑い腫瘍摘出術を試みたところ術中所見でクモ膜炎を疑わせる所見があり、病理所見では壊死巣を取り囲む肉芽組織が認められた。術後施行した髄液中梅毒血清反応は強陽性であり、梅毒によるCerebral Gummaと診断した。術 …
- NAID 110002278698
- 実験梅毒の免疫に関する研究-2-実験梅毒家兎抗体の胎児への移行
- 富沢 孝之,笠松 重雄,山屋 駿一
- 日本細菌学雑誌 21(4), 222-225, 1966
- … Female rabbits were injected intravenously with Treponema pallidum (Nichols strain) and bred after the infection became manifest. …
- NAID 130001382533
Related Links
- Treponemal infections symptoms, causes, diagnosis, and treatment information for Treponemal infections (Treponema infection) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and ...
- Inhibition of macrophage C3b-mediated ingestion by syphilitic hamster T cell-enriched fractions. J Immunol. 1984 Nov; 133(5):2698-705. [J Immunol. 1984] Cyclophosphamide-sensitive activity of suppressor T cells during treponemal ...
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| リンク元 | 「トレポネーマ感染症」「トレポネーマ感染」 |
| 関連記事 | 「infection」「treponemal」 |
「トレポネーマ感染症」
- 英
- treponemal infection
- 関
- ベジェル、トレ・ネーマ感染
「トレポネーマ感染」
- 英
- treponemal infection
- 関
- トレ・ネーマ感染症
「infection」
- n.
「treponemal」
- トレ・ネーマの