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関: Treponema

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spirochete that causes disease in humans (e.g. syphilis and yaws)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/10/29 08:05:18」(JST)

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Treponema is a bacterial genus. The major species is Treponema pallidum, whose subspecies are responsible for diseases such as syphilis and yaws.

The species Treponema hyodysenteriae and Treponema innocens have been reclassified into Serpulina hyodysenteriae and Serpulina innocens.^[1]

In the early 2000s they have again been reclassified into the family Brachyspiraceae.

Treponema paraluiscuniculi is associated with syphilis in rabbits.^[2]

Treponema carateum is the cause of pinta.^[3]

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) ^[4] and National Center for Biotechnology Information (NCBI)^[5] and the phylogeny is based on 16S rRNA-based LTP release 111 by 'The All-Species Living Tree' Project ^[6]

?T. calligyrum ♠ Noguchi

?T. carateum ♥ (pinta causing Treponema)

?T. minutum ♦ Dobell 1912

?T. pallidum ♦

	T. p. endemicum ♠ Smibert 1984 (bejel causing Treponema)

	T. p. pallidum ♠ (Schaudinn and Hoffmann 1905) Schaudinn 1905 (syphilis causing Treponema)

?T. paraluisleporis ♠ Lumeij et al. 1994

?T. paraluiscuniculi ♦ (Jacobsthal 1920) Smibert 1974

?T. pertenue ♦ (Castellani 1905) Castellani and Chalmers 1910 (yaws causing Treponema)

?T. phagedenis ♠

	T. p. phagedenis ♠ (Noguchi 1912) Brumpt

	T. p. vaccae ♠ Evans et al. 2006

?T. refringens ♠ (Schaudinn and Hofmann 1905) Castellani and Chalmers

?T. vincentii ♠ Smibert 1984

?T. zioleckii ♠ Piknova et al. 2008

	Spirochaeta caldaria Pohlschroeder et al. 1995

	Spirochaeta stenostrepta Zuelzer 1912

T. isoptericolens Dröge et al. 2008

	T. azotonutricium Graber et al. 2004

	T. primitia Graber et al. 2004

Spirochaeta zuelzerae (ex Veldkamp 1960) Canale-Parola 1980

T. medium

	T. m. bovis ♠ Evans et al. 2006

	T. m. medium ♠ Umemoto et al. 1997

T. pedis Evans et al. 2009

	T. denticola (ex Flügge 1886) Chan et al. 1993

	T. putidum Wyss et al. 2004

	T. lecithinolyticum Wyss et al. 1999

	T. maltophilum Wyss et al. 1996

T. brennaborense Schrank et al. 1999

T. saccharophilum Paster and Canale-Parola 1986

	T. berlinense Nordhoff et al. 2005

	T. pectinovorum Smibert and Burmeister 1983

T. bryantii Stanton and Canale-Parola 1980

	T. porcinum Nordhoff et al. 2005

	T. succinifaciens Cwyk and Canale-Parola 1981

T. parvum Wyss et al. 2001

T. amylovorum Wyss et al. 1997

T. socranskii

T. s. paredis Smibert et al. 1984

	T. s. buccale Smibert et al. 1984

	T. s. socranskii Smibert et al. 1984

Notes:
♦ Type strain lost or not available
♠ Strains found at the National Center for Biotechnology Information (NCBI) but not listed in the List of Prokaryotic names with Standing in Nomenclature (LSPN)
♥ Strains not lodged at National Center for Biotechnology Information (NCBI) or listed in the List of Prokaryotic names with Standing in Nomenclature (LPSN)

References

^ Stanton TB, Jensen NS, Casey TA, Tordoff LA, Dewhirst FE, Paster BJ (January 1991). "Reclassification of Treponema hyodysenteriae and Treponema innocens in a new genus, Serpula gen. nov., as Serpula hyodysenteriae comb. nov. and Serpula innocens comb. nov". Int. J. Syst. Bacteriol. 41 (1): 50–8. doi:10.1099/00207713-41-1-50. PMID 1704792.
^ Harper KN, Liu H, Ocampo PS, et al. (August 2008). "The sequence of the acidic repeat protein (arp) gene differentiates venereal from nonvenereal Treponema pallidum subspecies, and the gene has evolved under strong positive selection in the subspecies that causes syphilis". FEMS Immunol. Med. Microbiol. 53 (3): 322–32. doi:10.1111/j.1574-695X.2008.00427.x. PMID 18554302.
^ Antal GM, Lukehart SA, Meheus AZ (January 2002). "The endemic treponematoses". Microbes Infect. 4 (1): 83–94. doi:10.1016/S1286-4579(01)01513-1. PMID 11825779.
^ J.P. Euzéby. "Treponema". List of Prokaryotic names with Standing in Nomenclature (LPSN) [1]. Retrieved 2013-03-20.
^ Sayers et al. "Treponema". National Center for Biotechnology Information (NCBI) taxonomy database [2]. Retrieved 2013-03-20.
^ 'The All-Species Living Tree' Project."16S rRNA-based LTP release 111 (full tree)". Silva Comprehensive Ribosomal RNA Database [3]. Retrieved 2013-03-20.

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UpToDate Contents

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1. 梅毒の診断的検査 diagnostic testing for syphilis
2. 早期梅毒の病因、臨床症状、および治療 pathogenesis clinical manifestations and treatment of early syphilis
3. イチゴ腫、ベジェル、およびピンタ yaws bejel and pinta
4. 梅毒治療を受けている患者の臨床検査モニタリング laboratory monitoring of patients undergoing treatment for syphilis
5. 性器潰瘍患者へのアプローチ approach to the patient with genital ulcers

English Journal

Mapping the epidemiology of yaws in the solomon islands: a cluster randomized survey.

Marks M1, Vahi V2, Sokana O2, Puiahi E2, Pavluck A2, Zhang Z2, Dalipanda T2, Bottomley C2, Mabey DC2, Solomon AW2.
The American journal of tropical medicine and hygiene.Am J Trop Med Hyg.2015 Jan 7;92(1):129-33. doi: 10.4269/ajtmh.14-0438. Epub 2014 Nov 24.
Yaws, a non-venereal treponemal disease, is targeted for eradication by 2020 but accurate epidemiological data to guide control programs remain sparse. The Solomon Islands reports the second highest number of cases of yaws worldwide. We conducted a cluster randomized survey of yaws in two provinces
PMID 25422395

Performance Evaluation of the Elecsys Syphilis Assay for the Detection of Total Antibodies to Treponema pallidum.

Enders M1, Hunjet A1, Gleich M2, Imdahl R2, Mühlbacher A3, Schennach H3, Chaiwong K4, Sakuldamrongpanich T4, Turhan A5, Sertöz R5, Wolf E6, Mayer W7, Tao C8, Wang LL8, Semprini S9, Sambri V10.
Clinical and vaccine immunology : CVI.Clin Vaccine Immunol.2015 Jan;22(1):17-26. doi: 10.1128/CVI.00505-14. Epub 2014 Oct 29.
Syphilis is a health problem of increasing incidence in recent years that may have severe complications if not diagnosed and treated at an early stage. There are many diagnostic tests available for syphilis, but there is no gold standard, and diagnosis therefore usually relies upon a combination of
PMID 25355799

Comparison of a Combined Nontreponemal (VDRL) and Treponemal Immunoblot to Traditional Nontreponemal and Treponemal Assays.

Franken AA1, Oliver JH, Litwin CM.
Journal of clinical laboratory analysis.J Clin Lab Anal.2015 Jan;29(1):68-73. doi: 10.1002/jcla.21730. Epub 2014 Jan 3.
BACKGROUND: Serology is the mainstay for the diagnosis and management of patients with syphilis. Newer technologies such as immunoblotting are now available for the diagnosis of syphilis.METHODS: A commercial IgM/IgG immunoblot assay that detects both nontreponemal (VDRL-Venereal Disease Research La
PMID 24390867

Japanese Journal

Republication: Two Premature Neonates of Congenital Syphilis with Severe Clinical Manifestations

Tropical Medicine and Health 43(3), 165-170, 2015
NAID 130005102108

Republication: Two premature neonates of congenital syphilis with severe clinical manifestations

Tropical Medicine and Health advpub(0), 2015
NAID 130005076137

脳腫瘍と鑑別を要した中枢神経ゴム腫の1例

臨床神経学 54(9), 738-742, 2014
NAID 130004696175

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拡張検索	「treponemal infection」「nontreponemal antigen test」「treponemal antigen test」

「treponemal infection」

Treponema
	Treponema pallidum spirochaetes.
Scientific classification
Domain:	Bacteria
Phylum:	Spirochaetes
Class:	Spirochaetes Cavalier-Smith 2002
Order:	Spirochaetales Buchanan 1917
Family:	Spirochaetaceae Swellengrebel 1907
Genus:	Treponema Schaudinn 1905
Species
	Candidatus Treponema suis Molbak et al. 2006; Treponema amylovorum Wyss et al. 1997; Treponema azotonutricium Graber et al. 2004; Treponema berlinense Nordhoff et al. 2005; Treponema brennaborense Schrank et al. 1999; Treponema bryantii Stanton and Canale-Parola 1980; Treponema calligyrum ♠ Noguchi; Treponema carateum ♥; Treponema denticola (ex Flügge 1886) Chan et al. 1993; Treponema isoptericolens Dröge et al. 2008; Treponema lecithinolyticum Wyss et al. 1999; Treponema maltophilum Wyss et al. 1996; Treponema medium Umemoto et al. 1997; Treponema minutum ♦ Dobell 1912; Treponema pallidum ♦ (Schaudinn and Hoffmann 1905) Schaudinn 1905; Treponema paraluisleporis ♠ Lumeij et al. 1994; Treponema paraluiscuniculi ♦ (Jacobsthal 1920) Smibert 1974; Treponema parvum Wyss et al. 2001; Treponema pectinovorum Smibert and Burmeister 1983; Treponema pedis Evans et al. 2009; Treponema pertenue ♦ (Castellani 1905) Castellani and Chalmers 1910; Treponema phagedenis ♠ (Noguchi 1912) Brumpt; Treponema porcinum Nordhoff et al. 2005; Treponema primitia Graber et al. 2004; Treponema putidum Wyss et al. 2004; Treponema refringens ♠ (Schaudinn and Hofmann 1905) Castellani and Chalmers; Treponema saccharophilum Paster and Canale-Parola 1986; Treponema socranskii Smibert et al. 1984; Treponema succinifaciens Cwyk and Canale-Parola 1981; Treponema vincentii ♠ Smibert 1984; Treponema zioleckii ♠ Piknova et al. 2008;

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トレ・ネーマ感染症、トレ・ネーマ感染

関: bejel

「nontreponemal antigen test」

　　[★] 非トレポネーマ抗原検査

「treponemal antigen test」

　　[★] トレポネーマ抗原検査

[pmid1704792-1] Stanton TB, Jensen NS, Casey TA, Tordoff LA, Dewhirst FE, Paster BJ (January 1991). "Reclassification of Treponema hyodysenteriae and Treponema innocens in a new genus, Serpula gen. nov., as Serpula hyodysenteriae comb. nov. and Serpula innocens comb. nov". Int. J. Syst. Bacteriol. 41 (1): 50–8. doi:10.1099/00207713-41-1-50. PMID 1704792.

[pmid18554302-2] Harper KN, Liu H, Ocampo PS, et al. (August 2008). "The sequence of the acidic repeat protein (arp) gene differentiates venereal from nonvenereal Treponema pallidum subspecies, and the gene has evolved under strong positive selection in the subspecies that causes syphilis". FEMS Immunol. Med. Microbiol. 53 (3): 322–32. doi:10.1111/j.1574-695X.2008.00427.x. PMID 18554302.

[pmid11825779-3] Antal GM, Lukehart SA, Meheus AZ (January 2002). "The endemic treponematoses". Microbes Infect. 4 (1): 83–94. doi:10.1016/S1286-4579(01)01513-1. PMID 11825779.

[4] J.P. Euzéby. "Treponema". List of Prokaryotic names with Standing in Nomenclature (LPSN) [1]. Retrieved 2013-03-20.

[5] Sayers et al. "Treponema". National Center for Biotechnology Information (NCBI) taxonomy database [2]. Retrieved 2013-03-20.

[6] 'The All-Species Living Tree' Project."16S rRNA-based LTP release 111 (full tree)". Silva Comprehensive Ribosomal RNA Database [3]. Retrieved 2013-03-20.

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