thymine DNA glycosylase

チミンDNAグリコシラーゼ

WordNet

1. the 4th letter of the Roman alphabet (同)d
2. a base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine (同)T

PrepTutorEJDIC

1. deuteriumの化学記号
2. (胸腺のDNAからとる)白色結晶ピリミジン　チミン
3. deoxyribonucleic acidディオキシリボ核酸

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 分子遺伝学の原理 principles of molecular genetics
• 2. Prenatal screening for common aneuploidies using cell-free DNA
• 3. T-B-NK+ SCID：病因および遺伝学 t b nk scid pathogenesis and genetics
• 4. 遺伝性疾患の基本原則 basic principles of genetic disease
• 5. 遺伝学およびゲノミクスのためのツール：ポリメラーゼ連鎖反応 tools for genetics and genomics polymerase chain reaction

English Journal

• An amplified electrochemical strategy using DNA-QDs dendrimer superstructure for the detection of thymine DNA glycosylase activity.

• Liu H1, Lou Y2, Zhou F3, Zhu H3, Abdel-Halim ES4, Zhu JJ5.
• Biosensors & bioelectronics.Biosens Bioelectron.2015 Sep 15;71:249-55. doi: 10.1016/j.bios.2015.04.048. Epub 2015 Apr 20.
• A triple-signal amplification strategy was proposed for highly sensitive and selective detection of thymine DNA glycosylase (TDG) by coupling a dendrimer-like DNA label with the electrochemical method and quantum dots (QDs) tagging. The DNA-QDs dendrimer-like superstructure was designed by DNA hybri
• PMID 25913445

• Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice.

• Ghosh S1, Canugovi C1, Yoon JS2, Wilson DM 3rd1, Croteau DL1, Mattson MP2, Bohr VA3.
• Neurobiology of aging.Neurobiol Aging.2015 Jul;36(7):2319-30. doi: 10.1016/j.neurobiolaging.2015.04.004. Epub 2015 Apr 17.
• Oxidative DNA damage is mainly repaired by base excision repair (BER). Previously, our laboratory showed that mice lacking the BER glycosylases 8-oxoguanine glycosylase 1 (Ogg1) or nei endonuclease VIII-like 1 (Neil1) recover more poorly from focal ischemic stroke than wild-type mice. Here, a mouse
• PMID 25971543

• Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure.

• Lauritzen KH1, Kleppa L1, Aronsen JM2, Eide L1, Carlsen H1, Haugen ØP1, Sjaastad I3, Klungland A4, Rasmussen LJ5, Attramadal H6, Storm-Mathisen J1, Bergersen LH7.
• American journal of physiology. Heart and circulatory physiology.Am J Physiol Heart Circ Physiol.2015 Jun 8:ajpheart.00253.2014. doi: 10.1152/ajpheart.00253.2014. [Epub ahead of print]
• Cardiac mitochondrial dysfunction has been implicated in heart failure of diverse etiologies. Generalized mitochondrial disease also leads to cardiomyopathy with various clinical manifestations. Impaired mitochondrial homeostasis may over time, such as in the aging heart, lead to cardiac dysfunction
• PMID 26055793

Japanese Journal

• MyoD is regulated by the miR-29a-Tet1 pathway in C2C12 myoblast cells

• Journal of Oral Science 58(2), 219-229, 2016
• NAID 130005158882

• Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG

• BIOPHYSICS 10(0), 63-68, 2014
• NAID 130004699300

• Structural and functional properties of CiNTH, an endonuclease Ⅲ homologue of the ascidian Ciona intestinalis : critical role of N-terminal region

• Genes & genetic systems 87(2), 115-124, 2012-04-25
• NAID 10030616613

Related Links

• Thymine-DNA glycosylase - Wikipedia, the free encyclopedia

G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence homology with this protein.

• Thymine DNA glycosylase is essential for active DNA demethylation ...

Cell. 2011 Jul 8;146(1):67-79. doi: 10.1016/j.cell.2011.06.020. Epub 2011 Jun 30 . Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cortellino S, Xu J, Sannai M, Moore R, Caretti ...

---

★リンクテーブル★

リンク元	「チミンDNAグリコシラーゼ」
関連記事	「D」「DNA」「thymi」

「チミンDNAグリコシラーゼ」

　　[★]

英

thymine DNA glycosylase

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA

　

「thymi」

　　[★]

胸腺

関

thymic、thymus、thymus gland