tacrolimus-binding protein

• タクロリムス結合タンパク質、FK506結合タンパク質

関

FK506-binding protein、FKBP

WordNet

1. executed with proper legal authority; "a binding contract"
2. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
3. strip sewn over or along an edge for reinforcement or decoration
4. the capacity to attract and hold something
5. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

PrepTutorEJDIC

1. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
2. 蛋白(たんばく)質

UpToDate Contents

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• 1. 成人における肝移植：免疫抑制の概要 liver transplantation in adults overview of immunosuppression
• 2. 2型糖尿病の病因 pathogenesis of type 2 diabetes mellitus
• 3. 移植片対宿主病の予防および治療に使用される免疫抑制剤の概要 overview of immunosuppressive agents used for prevention and treatment of graft versus host disease
• 4. 成人の腎移植における免疫抑制維持療法 maintenance immunosuppressive therapy in renal transplantation in adults
• 5. 心臓移植における免疫抑制療法の導入および維持 induction and maintenance of immunosuppressive therapy in cardiac transplantation

English Journal

• Recombinant protein truncation strategy for inducing bactericidal antibodies to the macrophage infectivity potentiator protein of Neisseria meningitidis and circumventing potential cross-reactivity with human FK506-binding proteins.

• Bielecka MK1, Devos N2, Gilbert M2, Hung MC1, Weynants V2, Heckels JE1, Christodoulides M3.
• Infection and immunity.Infect Immun.2015 Feb;83(2):730-42. doi: 10.1128/IAI.01815-14. Epub 2014 Dec 1.
• A recombinant macrophage infectivity potentiator (rMIP) protein of Neisseria meningitidis induces significant serum bactericidal antibody production in mice and is a candidate meningococcal vaccine antigen. However, bioinformatics analysis of MIP showed some amino acid sequence similarity to human F
• PMID 25452551

• Selective inhibitors of the FK506-binding protein 51 by induced fit.

• Gaali S1, Kirschner A1, Cuboni S1, Hartmann J2, Kozany C1, Balsevich G2, Namendorf C1, Fernandez-Vizarra P2, Sippel C1, Zannas AS3, Draenert R4, Binder EB5, Almeida OF2, Rühter G6, Uhr M1, Schmidt MV2, Touma C2, Bracher A7, Hausch F1.
• Nature chemical biology.Nat Chem Biol.2015 Jan;11(1):33-7. doi: 10.1038/nchembio.1699. Epub 2014 Dec 1.
• The FK506-binding protein 51 (FKBP51, encoded by the FKBP5 gene) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the structurally similar but funct
• PMID 25436518

• Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.

• Yan Z1, Bai XC2, Yan C3, Wu J3, Li Z4, Xie T3, Peng W4, Yin CC5, Li X6, Scheres SH2, Shi Y3, Yan N4.
• Nature.Nature.2015 Jan 1;517(7532):50-5. doi: 10.1038/nature14063. Epub 2014 Dec 15.
• The ryanodine receptors (RyRs) are high-conductance intracellular Ca(2+) channels that play a pivotal role in the excitation-contraction coupling of skeletal and cardiac muscles. RyRs are the largest known ion channels, with a homotetrameric organization and approximately 5,000 residues in each prot
• PMID 25517095

Related Links

• Distribution and protein binding of FK506, a potent ...

1. J Pharm Pharmacol. 1994 Feb;46(2):113-7. Distribution and protein binding of FK506, a potent immunosuppressive macrolide lactone, in human blood and its uptake by erythrocytes. Nagase K, Iwasaki K, Nozaki K ...

• Plasma protein binding of tacrolimus in humans.

1. J Pharm Sci. 1993 Mar;82(3):340-1. Plasma protein binding of tacrolimus in humans. Piekoszewski W, Jusko WJ. Department of Pharmaceutics, School of Pharmacy, State University of New York, Buffalo 14260. An ...

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★リンクテーブル★

リンク元	「FK506結合タンパク質」「FKBP」「FK506-binding protein」「タクロリムス結合タンパク質」
拡張検索	「tacrolimus-binding protein 1A」
関連記事	「binding」「binding protein」

「FK506結合タンパク質」

　　[★]

英

FK506-binding protein、tacrolimus-binding protein、FKBP

関

タクロリムス結合タンパク質

-FKBP

関

FK-binding proteins

「FKBP」

　　[★]

• FK506結合タンパク質

関

FK506-binding protein、tacrolimus-binding protein

関

FK-binding proteins

「FK506-binding protein」

　　[★]

• FK506結合タンパク質

関

FKBP、tacrolimus-binding protein

「タクロリムス結合タンパク質」

　　[★]

英

tacrolimus-binding protein

関

FK506結合タンパク質

「tacrolimus-binding protein 1A」

　　[★]

• タクロリムス結合タンパク質1A

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「binding protein」

　　[★]

• 結合タンパク質、結合タンパク、結合蛋白質、結合蛋白

関

BP、carrier protein、transport protein