関: posterior leukoencephalopathy syndrome

WordNet

capable of reversing or being reversed; "reversible hypertension"
a garment (especially a coat) that can be worn inside out (with either side of the cloth showing)
capable of being reversed or used with either side out; "a reversible jacket" (同)two-sided
capable of assuming or producing either of two states; "a reversible chemical reaction"; "a reversible cell"
capable of being reversed; "a reversible decision is one that can be appealed or vacated"
located at or near or behind a part or near the end of a structure
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"

PrepTutorEJDIC

逆にできる / 裏返される,両面が使える / 裏返しても使える衣服
《名詞の前にのみ用いて》(生物学的に,位置が)後ろの,後部の / (時間・順序が)後の;(…より)後の《+『to』+『名』》(later) / しり(buttocks)
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/24 11:44:20」(JST)

wiki en

Posterior reversible encephalopathy syndrome (PRES), also known as reversible posterior leukoencephalopathy syndrome (RPLS), is a syndrome characterized by headache, confusion, seizures and visual loss. It may occur due to a number of causes, predominantly malignant hypertension, eclampsia and some medical treatments. On magnetic resonance imaging (MRI) of the brain, areas of edema (swelling) are seen. The symptoms tend to resolve after a period of time, although visual changes sometimes remain.^[1]^[2] It was first described in 1996.^[3]

Causes

Several factors appear to play a role in the pathogenesis of PRES, including immunosuppressive therapy, renal failure, eclampsia, severe high blood pressure,^[4] and lupus.^[5] Low magnesium levels can augment PRES.^{[citation needed]}

Signs and symptoms

Typical symptoms of PRES include headache, nausea, vomiting, altered mental status, seizures, stupor, and visual disturbances.^[4] Focal neurologic signs are uncommon in PRES.^[4]

Diagnosis

The diagnosis is typically made clinically, with supportive findings on magnetic resonance imaging of the brain; this may show hyperintensities on T₂-weighed imaging. Three different patterns have been described on MRI imaging.^[6] Cerebral angiography may provide a more definite diagnosis.^{[citation needed]}

Treatment

The treatment of PRES depends on the underlying cause. For instance, if the main problem is high blood pressure, blood pressure control will accelerate the resolution of the abnormalities. If the likely cause is medication, the withdrawal of the drug in question is needed.^[7]

Prognosis

Many cases resolve within 1–2 weeks of controlling the blood pressure and eliminating the inciting factor. However, long-lasting or even permanent neurologic dysfunction may remain. Though uncommon, death may occur with progressive swelling of the brain (cerebral edema) or a bleed in the brain (intracerebral hemorrhage).^{[citation needed]}

Epidemiology

The incidence of PRES is not currently known. Case reports suggest that there is no age predilection, with cases reported in people ages 2 to 90 years old. It may be somewhat more common in females.^{[citation needed]}

References

^ Garg RK (January 2001). "Posterior leukoencephalopathy syndrome". Postgrad Med J 77 (903): 24–8. doi:10.1136/pmj.77.903.24. PMC 1741870. PMID 11123390.
^ Pula JH, Eggenberger E (November 2008). "Posterior reversible encephalopathy syndrome". Curr Opin Ophthalmol 19 (6): 479–84. doi:10.1097/ICU.0b013e3283129746. PMID 18854692.
^ Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin M, Lamy C, Mas J, Caplan L (1996). "A reversible posterior leukoencephalopathy syndrome.". N Engl J Med 334 (8): 494–500. doi:10.1056/NEJM199602223340803. PMID 8559202.
^ ^a ^b ^c Rajasekhar, A.; George, T. J. (November 2007). "Gemcitabine-Induced Reversible Posterior Leukoencephalopathy Syndrome: A Case Report and Review of the Literature". The Oncologist 12 (11): 1332–1335. doi:10.1634/theoncologist.12-11-1332. PMID 18055853.
^ Kur, JK; Esdaile, JM (November 2006). "Posterior reversible encephalopathy syndrome--an underrecognized manifestation of systemic lupus erythematosus.". The Journal of rheumatology 33 (11): 2178–83. PMID 16960925.
^ Peter P, George A. Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci 2012;7:136-8.
^ Pedraza, R; Marik PE; Varon J (November 2009). "Posterior Reversible Encephalopathy Syndrome: A Review". Critical Care and Shock 12: 135–143.

UpToDate Contents

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1. 可逆性後白質脳症症候群 reversible posterior leukoencephalopathy syndrome
2. 成人における悪性高血圧および高血圧性脳症 malignant hypertension and hypertensive encephalopathy in adults
3. 妊娠中および周産期の重症疾患 critical illness during pregnancy and the peripartum period
4. 造血細胞移植レシピエントにおけるヒトヘルペスウイルス6感染 human herpesvirus 6 infection in hematopoietic cell transplant recipients
5. 急性痙攣発作に関連するMRIの変化 magnetic resonance imaging changes related to acute seizure activity

English Journal

Medication neurotoxicity in children.

Iyer RS, Chaturvedi A, Pruthi S, Khanna PC, Ishak GE.SourceDepartment of Radiology, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA, riyer@uw.edu.
Pediatric radiology.Pediatr Radiol.2011 Nov;41(11):1455-64. Epub 2011 Jul 23.
Medication neurotoxicity may have a variety of imaging manifestations in children. In this pictorial essay, we review the two most common brain injury patterns, posterior reversible encephalopathy syndrome (PRES) and acute toxic leukoencephalopathy (ATL). Proposed etiologies, salient features on neu
PMID 21785849

A case of posterior reversible encephalopathy syndrome after emergence from anesthesia.

Inoue S, Kawaguchi M, Furuya H.SourceDepartment of Anesthesiology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan, seninoue@naramed-u.ac.jp.
Journal of anesthesia.J Anesth.2011 Oct 20. [Epub ahead of print]
Posterior reversible encephalopathy syndrome (PRES) is a relatively new clinical entity characterized by reversible neurological symptoms with findings indicating leukoencephalopathy on imaging studies. Reports of PRES in the field of anesthesiology have been quite limited. A patient with therapeuti
PMID 22012172

Japanese Journal

Hypertensive Crisis in Young Woman with Takayasu Arteritis

Ogawa Osamu,Watanabe Ritsuo,Shimizu Hiroshi,Masani Fumiaki
Internal Medicine 50(18), 1963-1967, 2011
… The patients brain magnetic resonance image revealed reversible posterior leukoencephalopathy. …
NAID 130000969304

Reversible Cerebral Vasoconstriction Syndrome Presenting as Subarachnoid Hemorrhage, Reversible Posterior Leukoencephalopathy, and Cerebral Infarction

Noda Kazuyuki,Fukae Jiro,Fujishima Kenji,Mori Kentaro,Urabe Takao,Hattori Nobutaka,Okuma Yasuyuki
Internal Medicine 50(11), 1227-1233, 2011
… Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute severe headache with or without additional neurological symptoms and reversible cerebral vasoconstriction. …
NAID 130000770477

Related Pictures

★リンクテーブル★

リンク元	「可逆性後白質脳症症候群」「posterior leukoencephalopathy syndrome」
関連記事	「posterior」「reversible」「syndrome」

「可逆性後白質脳症症候群」

Posterior reversible encephalopathy syndrome
	Classification and external resources
	Posterior reversible encephalopathy syndrome visible on magnetic resonance imaging as multiple cortico-subcortical areas of T2-weighted hyperintense (white) signal involving the occipital and parietal lobes bilaterally and pons.
ICD-10	G93.4
ICD-9	348.39
DiseasesDB	10460
MeSH	D054038

　　[★]

英: reversible posterior leukoencephalopathy syndrome
関: 後部白質脳症症候群

「posterior leukoencephalopathy syndrome」

　　[★]

後部白質脳症症候群

関: reversible posterior leukoencephalopathy syndrome

「posterior」

　　[★]

adj.

後側の、後方の、後の

関: after、afterward、afterwards、backward、behind、following、late、post、posteriorly、subsequent

「reversible」

　　[★]

可逆的な、可逆性の、可逆

関: reversibility、reversibly

「syndrome」

　　[★]

n.

症候群

[Garg-1] Garg RK (January 2001). "Posterior leukoencephalopathy syndrome". Postgrad Med J 77 (903): 24–8. doi:10.1136/pmj.77.903.24. PMC 1741870. PMID 11123390.

[2] Pula JH, Eggenberger E (November 2008). "Posterior reversible encephalopathy syndrome". Curr Opin Ophthalmol 19 (6): 479–84. doi:10.1097/ICU.0b013e3283129746. PMID 18854692.

[Hinchey-3] Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin M, Lamy C, Mas J, Caplan L (1996). "A reversible posterior leukoencephalopathy syndrome.". N Engl J Med 334 (8): 494–500. doi:10.1056/NEJM199602223340803. PMID 8559202.

[Rajasekhar-4] Rajasekhar, A.; George, T. J. (November 2007). "Gemcitabine-Induced Reversible Posterior Leukoencephalopathy Syndrome: A Case Report and Review of the Literature". The Oncologist 12 (11): 1332–1335. doi:10.1634/theoncologist.12-11-1332. PMID 18055853.

[5] Kur, JK; Esdaile, JM (November 2006). "Posterior reversible encephalopathy syndrome--an underrecognized manifestation of systemic lupus erythematosus.". The Journal of rheumatology 33 (11): 2178–83. PMID 16960925.

[6] Peter P, George A. Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci 2012;7:136-8.

[7] Pedraza, R; Marik PE; Varon J (November 2009). "Posterior Reversible Encephalopathy Syndrome: A Review". Critical Care and Shock 12: 135–143.

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案内

reversible posterior leukoencephalopathy syndrome