治療抵抗性B細胞性リンパ腫
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- temporarily unresponsive or not fully responsive to nervous or sexual stimuli; "the refractory period of a muscle fiber"
- not responding to treatment; "a stubborn infection"; "a refractory case of acne"; "stubborn rust stains" (同)stubborn
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- (人などが)手に負えない,強情な / (病気が)治りにくい,がんこな / (金属などが)溶けにくい,耐火性の
- 屈折媒体(レンズ) / =refracting telescope
UpToDate Contents
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English Journal
- Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma.
- Mareschal S1, Dubois S1, Viailly PJ1,2, Bertrand P1, Bohers E1, Maingonnat C1, Jaïs JP3, Tesson B4, Ruminy P1, Peyrouze P5, Copie-Bergman C6, Fest T7, Jo Molina T8, Haioun C9, Salles G10, Tilly H1, Lecroq T2, Leroy K6, Jardin F1.
- Genes, chromosomes & cancer.Genes Chromosomes Cancer.2016 Mar;55(3):251-67. doi: 10.1002/gcc.22328. Epub 2015 Nov 26.
- Despite the many efforts already spent to enumerate somatic mutations in diffuse large B-cell lymphoma (DLBCL), previous whole-genome and whole-exome studies conducted on patients of mixed outcomes failed at characterizing the 30% of patients who will relapse or resist current immunochemotherapies.
- PMID 26608593
- Chronic Lymphocytic Leukemia and Other Lymphoproliferative Disorders.
- Wall S1, Woyach JA2.
- Clinics in geriatric medicine.Clin Geriatr Med.2016 Feb;32(1):175-89. doi: 10.1016/j.cger.2015.08.006.
- Chronic lymphocytic leukemia affects less than 1% of US adults but is the most common leukemia and primarily affects older patients. Non-Hodgkin lymphomas are the seventh most common cancers in the United States and also primarily affect older patients. In general, older patients should be treated d
- PMID 26614867
- Vorinostat, a histone deacetylase (HDAC) inhibitor, promotes cell cycle arrest and re-sensitizes rituximab- and chemo-resistant lymphoma cells to chemotherapy agents.
- Xue K1,2, Gu JJ3, Zhang Q1,2, Mavis C3, Hernandez-Ilizaliturri FJ3, Czuczman MS3, Guo Y4,5.
- Journal of cancer research and clinical oncology.J Cancer Res Clin Oncol.2016 Feb;142(2):379-87. doi: 10.1007/s00432-015-2026-y. Epub 2015 Aug 28.
- PURPOSE: Preclinical models of chemotherapy resistance and clinical observations derived from the prospective multicenter phase III collaborative trial in relapsed aggressive lymphoma (CORAL) study demonstrated that primary refractory/relapsed B cell diffuse large B cell lymphoma has a poor clinical
- PMID 26314218
Japanese Journal
- 新規抗体/薬物複合体によるリンパ系腫瘍の治療 : イノツズマブ・オゾガマイシンとブレンツキシマブ・ベドチン (特集 新規ターゲットおよび医薬品による血液がん治療の新たな展開)
- リンパ腫と造血幹細胞移植:当施設の治療経験も含めて
Related Links
- Relapsed-Refractory Diffuse Large B Cell Lymphoma (RR DLBCL), which accounts for approximately one-third of patients with DLBCL, remains a major cause of morbidity and mortality. Managing RR DLBCL continues to be a ...
- The ongoing multicenter phase III CORAL (Collaborative Trial in Relapsed Aggressive Lymphoma) study, aims to further guide the choice of salvage chemotherapy in diffuse large B-cell lymphoma (DLBCL) and assess the role of ...
★リンクテーブル★
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- 英
- refractory B-cell lymphoma
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- 手に負えない、御しがたい
- (病気などが)難治性の、抗療性の。(刺激に)不応性の、無反応性の。抵抗性がある、免疫性の(to)
- 関
- intractable、inveterate、recalcitrance、recalcitrant、refractoriness、resistance、resistant、resistive
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- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
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細胞