WordNet

remove the pulp from, as from a fruit
a soft moist part of a fruit (同)flesh
a mixture of cellulose fibers
reduce to pulp; "pulp fruit"; "pulp wood"
any soft or soggy mass; "he pounded it to a pulp" (同)mush
an inexpensive magazine printed on poor quality paper (同)pulp magazine
the soft inner part of a tooth
of a color at the end of the color spectrum (next to orange); resembling the color of blood or cherries or tomatoes or rubies (同)reddish, ruddy, blood-red, carmine, cerise, cherry, cherry-red, crimson, ruby, ruby-red, scarlet
red color or pigment; the chromatic color resembling the hue of blood (同)redness
the syllable naming the second (supertonic) note of any major scale in solmization (同)ray
a tributary of the Mississippi River that flows eastward from Texas along the southern boundary of Oklahoma and through Louisiana (同)Red River
100 puls equal 1 afghani in Afghanistan

PrepTutorEJDIC

〈U〉(果実・野菜などの)果肉 / 〈U〉髄質(骨髄・歯髄など) / 〈U〉(製紙原料の)パルプ / 〈U〉《時にa~》どろどろしたもの / 《しばしば複数形で》(粗末な紙にきわもの記事を印刷した)低俗雑誌 / …‘を'パルプにする;…‘を'どろどろにする
〈U〉〈C〉『赤,』『赤色;』赤い絵の具(染料) / 〈U〉赤い服 / 〈C〉《しばしば『R-』》《話》《時に軽べつして》アカ,共産主義者;過激論(主義)者 / 〈U〉《通例the ~》(会計の)赤字,負債 / 『赤い』,赤色の / (顔・目などが)赤くなった;血に染った / 赤い服を着た;赤毛の / 《しばしば『R-』》《話》《軽べつして》共産主義の;過激な
レ(全音階の第2音)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/20 13:46:11」(JST)

wiki en

The red pulp of the spleen is composed of connective tissue known as the cords of Billroth and many splenic sinuses that are engorged with blood, giving it a red color.^[1]^[2] Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells.^[3]

The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp.^[4] Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma.^[1]

Sinusoids

The splenic sinuses of the spleen, also known as sinusoids, are wide vessels that drain into trabecular veins. Gaps in the endothelium lining the sinusoids mechanically filter blood cells as they enter the spleen. Worn-out or abnormal red cells attempting to squeeze through the narrow intercellular spaces become badly damaged, and are subsequently devoured by macrophages in the red pulp.^[5] In addition to aged red blood cells, the sinusoids also filter out particles that could clutter up the bloodstream, such as nuclear remnants, platelets, or denatured hemoglobin.

Cells found in red pulp

Red pulp consists of a dense network of fine reticular fiber, continuous with those of the splenic trabeculae, to which are applied flat, branching cells. The meshes of the reticulum are filled with blood:

White corpuscles are found to be in larger proportion than they are in ordinary blood.
Large rounded cells, termed splenic cells, are also seen; these are capable of ameboid movement, and often contain pigment and red-blood corpuscles in their interior.
The cells of the reticulum each possess a round or oval nucleus, and like the splenic cells, they may contain pigment granules in their cytoplasm; they do not stain deeply with carmine, and in this respect differ from the cells of the Malpighian corpuscles.
In the young spleen, macrophages may also be found, each containing numerous nuclei or one compound nucleus.
Nucleated red-blood corpuscles have also been found in the spleen of young animals.

Diseases

In lymphoid leukemia, the white pulp of the spleen hypertrophies and the red pulp shrinks.^[4] In some cases the white pulp can swell to 50% of the total volume of the spleen.^[6] In myeloid leukemia, the white pulp atrophies and the red pulp expands.^[4]

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

^ ^a ^b Luiz Carlos Junqueira and José Carneiro (2005). Basic histology: text & atlas. McGraw-Hill Professional. pp. 274–277. ISBN 0-07-144091-7.
^ Michael Schuenke, Erik Schulte, Udo Schumacher, Lawrence M. Ross, Edward D. Lamperti (2006). Atlas of anatomy: neck and internal organs. Thieme. p. 219. ISBN 1-58890-360-5.
^ Victor P. Eroschenko, Mariano S. H. di Fiore (2008). Di Fiore's atlas of histology with functional correlations. Lippincott Williams & Wilkins. p. 208. ISBN 0-7817-7057-2.
^ ^a ^b ^c Carl Pochedly, Richard H. Sills, Allen D. Schwartz (1989). Disorders of the spleen: pathophysiology and management. Informa Health Care. pp. 7–15. ISBN 0-8247-7933-9.
^ Cormack, David H. (2001). Essential histology. Lippincott Williams & Wilkins. pp. 169–170. ISBN 0-7817-1668-3.
^ Jan Klein, Václav Hořejší (1997). Immunology. Wiley-Blackwell. p. 30. ISBN 0-632-05468-9.

External links

Anatomy Atlases - Microscopic Anatomy, plate 09.175 - "Spleen: Red Pulp"
Diagram at kctcs.edu
Description and diagram at apsu.edu

UpToDate Contents

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1. 赤血球細胞の力学 red blood cell mechanics
2. 成人における赤血球輸血：保管、専門的調整、および輸血パラメータ red blood cell transfusion in adults storage specialized modifications and infusion parameters
3. 有毛細胞白血病の臨床的特徴および診断 clinical features and diagnosis of hairy cell leukemia
4. 赤血球水分量の制御 control of red blood cell hydration
5. 新生児における赤血球輸血 red blood cell transfusions in the newborn

English Journal

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles.

Ergen C1, Heymann F1, Al Rawashdeh W2, Gremse F2, Bartneck M1, Panzer U3, Pola R4, Pechar M4, Storm G5, Mohr N6, Barz M6, Zentel R6, Kiessling F2, Trautwein C1, Lammers T7, Tacke F8.
Biomaterials.Biomaterials.2017 Jan;114:106-120. doi: 10.1016/j.biomaterials.2016.11.009. Epub 2016 Nov 9.
Identifying intended or accidental cellular targets for drug delivery systems is highly relevant for evaluating therapeutic and toxic effects. However, limited knowledge exists on the distribution of nano- and micrometer-sized carrier systems at the cellular level in different organs. We hypothesize
PMID 27855336

Behaviour of human dental pulp cells cultured in a collagen hydrogel scaffold cross-linked with cinnamaldehyde.

Kwon YS1, Lee SH1, Hwang YC2, Rosa V3, Lee KW1,4, Min KS1,4.
International endodontic journal.Int Endod J.2017 Jan;50(1):58-66. doi: 10.1111/iej.12592. Epub 2016 Jan 6.
AIM: To investigate the effects of the cross-linking agent cinnamaldehyde (CA) on differentiation of human dental pulp cells (hDPCs) cultured in a collagen hydrogel, which may be useful as a scaffold for regenerative endodontic therapy.METHODOLOGY: The odontogenic potential of hDPCs exposed to CA wa
PMID 26650820

Pulpal Tissue Inflammatory Reactions after Experimental Pulpal Exposure in Mice.

He Y1, Gan Y2, Lu J1, Feng Q1, Wang H1, Guan H1, Jiang Q3.
Journal of endodontics.J Endod.2017 Jan;43(1):90-95. doi: 10.1016/j.joen.2016.09.003. Epub 2016 Nov 17.
INTRODUCTION: The purpose of this study was to establish a stable experimental mice pulpal inflammatory model and to evaluate inflammatory reactions of pulpal tissue after pulpal exposure.METHODS: Pulpal inflammation was induced in 80 C57BL/6 mice by occlusal exposure of the pulp of the maxillary fi
PMID 27866710

Japanese Journal

Functions and development of red pulp macrophages

Kurotaki Daisuke,Uede Toshimitsu,Tamura Tomohiko
Microbiology and immunology 59(2), 55-62, 2015-02
NAID 40020388159

A Long-Term High-Fat Diet Changes Iron Distribution in the Body, Increasing Iron Accumulation Specifically in the Mouse Spleen

, , [他], , , , , , ,
Journal of Nutritional Science and Vitaminology 61(1), 20-27, 2015
… Increased percentages of the splenic red pulp and macrophages were observed in HFD-fed mice and iron accumulation in the spleen was found mainly in the splenic red pulp. …
NAID 130005070829

ヒト歯髄細胞の代謝に対する低出力半導体レーザー照射の影響

國松亮,郡司秀美,柄優至,吉見友希,中島健吾,谷本幸太郎
日本レーザー歯学会誌 26(1), 1-9, 2015
… Laser irradiation activates a range of cellular processes in a variety of cell types, including stem cells, and can promote tissue repair.The purpose of this study was to examine the effects of diode laser irradiation on the proliferation and osteogenic differentiation of human dental pulp cells (hDPCs). … Mineralization was evaluated by Alizarin Red staining. …
NAID 130005065069

Related Pictures

★リンクテーブル★

リンク元	「赤脾髄」
拡張検索	「splenic red pulp」
関連記事	「pulp」「red」

「赤脾髄」

Red pulp
	Transverse section of a portion of the spleen. (Spleen pulp labeled at lower right.)
	Spleen
Details
Latin	pulpa splenica
Identifiers
Gray's	p.1284
Dorlands; /Elsevier	p_41/12679479
FMA	15844
	Anatomical terminology