pyrimidine dimer-specific endonuclease

• ピリミジンダイマー特異的エンドヌクレアーゼ

関

endonuclease V

WordNet

1. stated explicitly or in detail; "needed a specific amount"
2. a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
3. (sometimes followed by `to'
4. being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
5. relating to or distinguishing or constituting a taxonomic species; "specific characters"
6. lacking in light; not bright or harsh; "a dim light beside the bed"; "subdued lights and soft music" (同)subdued
7. become dim or lusterless; "the lights dimmed and the curtain rose"
8. make dim or lusterless; "Time had dimmed the silver"
9. switch (a cars headlights) from a higher to a lower beam (同)dip
10. lacking clarity or distinctness; "a dim figure in the distance"; "only a faint recollection"; "shadowy figures in the gloom"; "saw a vague outline of a building through the fog"; "a few wispy memories of childhood" (同)faint, shadowy, vague, wispy
11. a heterocyclic organic compound with a penetrating odor
12. any of several basic compounds derived from pyrimidine
13. a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
14. a United States coin worth one tenth of a dollar

PrepTutorEJDIC

1. 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
2. 『薄暗い』,ほの暗い / はっきり見えない(聞こえない,理解できない) / (考え・記憶などが)はっきりしない,ぼんやりした / (色などが)くすんだ,光沢のない / 批判的な,悲観的な / 《話》(人が)ばかな,愚かな / (目が)かすんだ / …‘を'『薄暗くする』,ぼんやりさせる / 『薄暗くなる』,かすかになる
3. ダイム(米国およびカナダの10セント銀貨)

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English Journal

• Mutagenesis during plant responses to UVB radiation.

• Holá M1, Vágnerová R1, Angelis KJ2.
• Plant physiology and biochemistry : PPB / Société française de physiologie végétale.Plant Physiol Biochem.2015 Aug;93:29-33. doi: 10.1016/j.plaphy.2014.12.013. Epub 2014 Dec 17.
• We tested an idea that induced mutagenesis due to unrepaired DNA lesions, here the UV photoproducts, underlies the impact of UVB irradiation on plant phenotype. For this purpose we used protonemal culture of the moss Physcomitrella patens with 50% of apical cells, which mimics actively growing tissu
• PMID 25542779

• Interaction of T4 endonuclease V with DNA: importance of the flexible loop regions in protein-DNA interaction.

• Ahn HC1, Ohkubo T, Iwai S, Morikawa K, Lee BJ.
• The Journal of biological chemistry.J Biol Chem.2003 Aug 15;278(33):30985-92. Epub 2003 Jun 3.
• T4 endonuclease V (T4 endo V), a thymine dimer-specific DNA repair enzyme, and its interaction with DNA were investigated by nuclear magnetic resonance (NMR) spectroscopy. Backbone resonance assignment, chemical shift mapping, and 15N relaxation measurements were employed to the free and DNA-bound e
• PMID 12783877

• The Arabidopsis UVH1 gene is a homolog of the yeast repair endonuclease RAD1.

• Fidantsef AL1, Mitchell DL, Britt AB.
• Plant physiology.Plant Physiol.2000 Oct;124(2):579-86.
• Ultraviolet radiation induces DNA damage products, largely in the form of pyrimidine dimers, that are both toxic and mutagenic. In most organisms, including Arabidopsis, these lesions are repaired both through a dimer-specific photoreactivation mechanism and through a less efficient light-independen
• PMID 11027708

Japanese Journal

• Specific interaction between damaged bases in DNA and repair enzymes (第9回公開シンポジウム モデルDNA損傷と変異機構)

• Morikawa Kosuke
• 環境変異原研究 20(3), 229-234, 1998-10-31
• … T4 endonuclease V is a DNA repair enzyme from bacteriophage T4 which catalyzes the first reaction step of the pyrimidine dimer specific base excision repair pathway. … The crystal structure of the enzyme complexed with a duplex DNA substrate, containing a thymine dimer, has been determined at 2.75Å resolution. …
• NAID 110001713576

• Biochemical studies on radiation-sensitive mutations in bacteriophage T4.

• ,
• The Journal of Biochemistry 77(2), 303-311, 1975
• … Mutants of bacteriophage T4 which exhibit increased sensitivity to ultraviolet radia-tion were isolated and their abilities to induce an enzyme system to excise pyrimidine dimers were examined. … Among 16 mutants isolated, 12 mutants were found to be defective in inducing T4 endonuclease V, which catalyzes the formation of dimer-specific breaks in ultraviolet-irradiated DNA. …
• NAID 130003539568

Related Links

• LSDシソーラス: ピリミジンダイマー特異的エンドヌクレアーゼ ...

LSDシソーラス: ピリミジンダイマー特異的エンドヌクレアーゼ Pyrimidine Dimer-specific endonuclease

• Purification and properties of a pyrimidine dimer-specific ...

[Show abstract] [Hide abstract] ABSTRACT: Recent studies have shown purified preparations of phage T4 UV DNA-incising activity (T4 UV endonuclease or endonuclease V of phage T4) contain a pyrimidine dimer-DNA glycosylase ...

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★リンクテーブル★

リンク元	「ピリミジンダイマー特異的エンドヌクレアーゼ」「endonuclease V」
関連記事	「specific」「dim」「endonuclease」

「ピリミジンダイマー特異的エンドヌクレアーゼ」

　　[★]

英

pyrimidine dimer-specific endonuclease

関

エンドヌクレアーゼV

「endonuclease V」

　　[★]

エンドヌクレアーゼV

関

pyrimidine dimer-specific endonuclease

「specific」

　　[★]

• adj.

• (～に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
• (比較)(限定)特定の(particular)、一定の(⇔general)
• (～に)特有の、独特の(to)
• (比較)(医学)(～に)渡航のある(for)。特殊な
• (生物)(生物)種の
• 医学)特異の
• (物理)比の。物質固有の。単位質量・長さ・面積・容積で

n.

関

specifically、specificity

　 　 　 　 　 　

「dim」

　　[★]

• adj.

• 薄暗い、(音が)かすかな

関

faint、faintly、subtle、subtly

　 　 　 　 　 　

「endonuclease」

　　[★]

エンドヌクレアーゼ、・リヌクレオチド内部加水分解酵素