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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/03/27 00:04:34」(JST)
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English Journal
- A novel frameshift mutation of epithelial sodium channel β-subunit leads to Liddle syndrome in an isolated case.
- Yang KQ1, Lu CX, Xiao Y, Liu YX, Jiang XJ, Zhang X, Zhou XL.
- Clinical endocrinology.Clin Endocrinol (Oxf).2015 Apr;82(4):611-4. doi: 10.1111/cen.12650. Epub 2015 Jan 6.
- OBJECTIVE: Liddle syndrome, an autosomal dominant form of monogenic hypertension, is attributed to mutations in the genes encoding β and γ subunits (SCNN1B and SCNN1G) of the epithelial sodium channel (ENaC). The aim of this study was to search for pathogenic mutations of SCNN1B and SCNN1G in an a
- PMID 25378078
- A pitfall in diagnosing Cushing's disease: ectopic ACTH-producing pituitary adenoma in the sphenoid sinus.
- Flitsch J1, Schmid SM, Bernreuther C, Winterberg B, Ritter MM, Lehnert H, Burkhardt T.
- Pituitary.Pituitary.2015 Apr;18(2):279-82. doi: 10.1007/s11102-014-0591-8.
- PURPOSE: To show a rare case of Cushing's disease and possible cause of failed transsphenoidal surgery.METHOD: We report on a 50-year-old woman suffering from ACTH-dependent Cushing's syndrome. Endocrinological work-up including low-dose/high-dose dexamethasone test (Liddle-test) and CRH test were c
- PMID 25129688
- Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
- Fang S1, Suh JM1, Reilly SM2, Yu E1, Osborn O3, Lackey D3, Yoshihara E1, Perino A4, Jacinto S1, Lukasheva Y1, Atkins AR1, Khvat A5, Schnabl B3, Yu RT1, Brenner DA3, Coulter S6, Liddle C6, Schoonjans K4, Olefsky JM3, Saltiel AR2, Downes M1, Evans RM7.
- Nature medicine.Nat Med.2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5.
- The systemic expression of the bile acid (BA) sensor farnesoid X receptor (FXR) has led to promising new therapies targeting cholesterol metabolism, triglyceride production, hepatic steatosis and biliary cholestasis. In contrast to systemic therapy, bile acid release during a meal selectively activa
- PMID 25559344
Japanese Journal
- こむら返りに対する四物湯エキスの有用性
- 日本東洋医学雑誌 66(3), 244-249, 2015
- NAID 130005108247
- 甘草の使用量と偽アルドステロン症の頻度に関する文献的調査
- 日本東洋医学雑誌 66(3), 197-202, 2015
- NAID 130005108239
- 「PMDA 医薬品副作用データベース」を利用した漢方製剤の 副作用の解析
- 医薬品情報学 16(1), 16-22, 2014
- NAID 130004941480
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Related Pictures
★リンクテーブル★
| リンク元 | 「偽性アルドステロン症」 |
「偽性アルドステロン症」
概念
- 血中アルドステロン濃度は低値にもかかわらず、原発性アルドステロン症と同様の症状を呈する病態
病因
- グリチルリチンは腎臓において11β-ヒドロキシステロイド脱水素酵素(コルチゾールをコルチゾンに変換して不活化)を阻害する結果、腎臓におけるコルチゾールの鉱質コルチコイド様作用が亢進する。