protein tyrosine kinase

関

tyrosine kinases

WordNet

1. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
2. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
3. an amino acid found in most proteins; a precursor of several hormones
4. the basic unit of money in Papua New Guinea

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1. 蛋白(たんばく)質

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• 1. 慢性骨髄性白血病に対するチロシンキナーゼ阻害剤の臨床使用 clinical use of tyrosine kinase inhibitors for chronic myeloid leukemia
• 2. 慢性骨髄性白血病の治療の概要 overview of the treatment of chronic myeloid leukemia
• 3. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
• 4. 進行消化管間質腫瘍に対するチロシンキナーゼ阻害剤療法 tyrosine kinase inhibitor therapy for advanced gastrointestinal stromal tumors
• 5. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation

English Journal

• Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.

• Fred RG, Boddeti SK, Lundberg M, Welsh N.
• Clinical science (London, England : 1979).Clin Sci (Lond).2015 Jan;128(1):17-28. doi: 10.1042/CS20130560.
• Low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic and multi-functional type I cell surface membrane protein, which is known to be phosphorylated by the activated platelet-derived growth factor receptor (PDGFR). The tyrosine kinase inhibitor imatinib, which inhibits PDGFR and
• PMID 24865476

• Bone-induced c-kit expression in prostate cancer: A driver of intraosseous tumor growth.

• Mainetti LE1, Zhe X, Diedrich J, Saliganan AD, Cho WJ, Cher ML, Heath E, Fridman R, Kim HR, Bonfil RD.
• International journal of cancer. Journal international du cancer.Int J Cancer.2015 Jan 1;136(1):11-20. doi: 10.1002/ijc.28948. Epub 2014 May 20.
• Loss of BRCA2 function stimulates prostate cancer (PCa) cell invasion and is associated with more aggressive and metastatic tumors in PCa patients. Concurrently, the receptor tyrosine kinase c-kit is highly expressed in skeletal metastases of PCa patients and induced in PCa cells placed into the bon
• PMID 24798488

• Measuring sulfatase expression and invasion in glioblastoma.

• Wade A1, Engler JR, Tran VM, Phillips JJ.
• Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2015;1229:507-16. doi: 10.1007/978-1-4939-1714-3_39.
• Extracellular sulfatases (SULF1 and SULF2) selectively remove 6-O-sulfate groups from heparan sulfate proteoglycans (HSPGs) and by this process control important interactions of HSPGs with extracellular factors including morphogens, growth factors, and extracellular matrix components. The expression
• PMID 25325976

Japanese Journal

• Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection

• Nabekura Tsukasa,Kanaya Minoru,Shibuya Akira,Fu Guo,Gascoigne Nicholas R.J.,Lanier Lewis L.,渋谷 彰
• Immunity 40(2), 225-234, 2014-02
• … Src-family tyrosine kinase Fyn and serine-threonine protein kinase C isoform eta (PKCη) signaling through DNAM-1 played distinct roles in the generation of MCMV-specific effector and memory NK cells. …
• NAID 120005425984

• Melatonin regulates human bone sialoprotein gene transcription

• Matsumura Hiroyoshi,Ogata Yorimasa
• Journal of Oral Science 56(1), 67-76, 2014
• … Bone sialoprotein (BSP) is a mineralized connective tissue-specific protein expressed in the early stage of cementum and bone mineralization. … The effects of melatonin were suppressed by protein kinase A, tyrosine kinase, ERK1/2 and phosphatidylinositol 3-kinase inhibitors. …
• NAID 130003393080

• Desensitization by Different Strategies of Epidermal Growth Factor Receptor and ErbB4

• Yamamoto Hideyuki,Higa-Nakamine Sayomi,Noguchi Nobuhiro,Maeda Noriko,Kondo Yutaka,Toku Seikichi,Kukita Ichiro,Sugahara Kazuhiro
• Journal of Pharmacological Sciences, 2014
• … Four transmembrane tyrosine kinases constitute the ErbB protein family: epidermal growth factor receptor (EGFR) or ErbB1, ErbB2, ErbB3, and ErbB4. … It has been reported that heterologous desensitization of EGFR is induced by serine phosphorylation of EGFR via the p38 mitogen-activated protein kinase (p38 MAP kinase) pathway in various cell lines, including alveolar epithelial cells. …
• NAID 130003391497

Related Links

• Protein Kinases : Introduction - Cell Signal

Protein Kinases : Introduction - Cell Signal

• Protein kinaseとは - goo Wikipedia (ウィキペディア)

Tyrosine-specific protein kinases (EC 2.7.10.1 and EC 2.7.10.2) phosphorylate tyrosine amino acid residues, and like serine/threonine-specific kinases are used in signal transduction. They act primarily as growth factor receptors and ...

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★リンクテーブル★

リンク元	「チロシンキナーゼ」
拡張検索	「receptor protein-tyrosine kinase」「Src protein-tyrosine kinase」「focal adhesion protein-tyrosine kinase」「protein-tyrosine kinase」「ZAP-70 protein-tyrosine kinase」
関連記事	「kinase」

「チロシンキナーゼ」

　　[★]

英

tyrosine kinase

同

チロシンプロテインキナーゼ tyrosine protein kinase、タンパク質チロシンキナーゼ 蛋白質チロシンキナーゼ protein tyrosine kinase PTK

関

Vatalanib、プロテインキナーゼ

「receptor protein-tyrosine kinase」

　　[★]

• レセプター型チロシンキナーゼ、チロシンキナーゼ共役型受容体

関

receptor tyrosine kinase、tyrosine kinase receptor

「Src protein-tyrosine kinase」

　　[★]

• Srcタンパク質チロシンキナーゼ

関

Src kinase、Src tyrosine kinase、Src-family kinase、Src-family tyrosine kinase

「focal adhesion protein-tyrosine kinase」

　　[★]

接着斑キナーゼ、フォーカルアドヒージョンキナーゼ

関

FAK、focal adhesion kinase

「protein-tyrosine kinase」

　　[★]

タンパク質チロシンキナーゼ

関

tyrosine kinase

「ZAP-70 protein-tyrosine kinase」

　　[★]

ZAP-70チロシンキナーゼ

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase