Src tyrosine kinase

• Srcチロシンキナーゼ

関

Src kinase、Src protein-tyrosine kinase、Src-family kinase、Src-family tyrosine kinase

WordNet

1. the 19th letter of the Roman alphabet (同)s
2. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
3. an amino acid found in most proteins; a precursor of several hormones
4. the basic unit of money in Papua New Guinea

PrepTutorEJDIC

1. sulfurの化学記号 / {略}South[ern]
2. strontiumの化学記号

UpToDate Contents

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• 1. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
• 2. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
• 3. Chemotherapy nephrotoxicity and dose modification in patients with renal insufficiency: Molecularly targeted agents
• 4. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
• 5. ZAP-70欠損症 zap 70 deficiency

English Journal

• Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src.

• Diao Y1, Ma X1, Min W1, Lin S1, Kang H1, Dai Z1, Wang X1, Zhao Y2.
• Cancer letters.Cancer Lett.2016 Aug 28;379(1):12-23. doi: 10.1016/j.canlet.2016.05.003. Epub 2016 May 16.
• Cisplatin and paclitaxel are considered to be the backbone of chemotherapy in lung adenocarcinoma. These agents show pleiotropic effects on cell death. However, the precise mechanisms remain unclear. The present study reported that phosphorylated caspase-8 at tyrosine 380 (p-Casp8) was characterized
• PMID 27195913

• Integrin αvβ3 expression in tongue squamous carcinoma cells Cal27 confers anticancer drug resistance through loss of pSrc(Y418).

• Stojanović N1, Brozovic A1, Majhen D1, Bosnar MH2, Fritz G3, Osmak M1, Ambriović-Ristov A1.
• Biochimica et biophysica acta.Biochim Biophys Acta.2016 Aug;1863(8):1969-78. doi: 10.1016/j.bbamcr.2016.04.019. Epub 2016 Apr 21.
• Integrins play key roles in the regulation of tumor cell adhesion, migration, invasion and sensitivity to anticancer drugs. In the present study we investigate the mechanism of resistance of tongue squamous carcinoma cells Cal27 with de novo integrin αvβ3 expression to anticancer drugs. Cal27-deri
• PMID 27108184

• Bivalent Inhibitors of c-Src Tyrosine Kinase That Bind a Regulatory Domain.

• Johnson TK1, Soellner MB1.
• Bioconjugate chemistry.Bioconjug Chem.2016 Jul 20;27(7):1745-9. doi: 10.1021/acs.bioconjchem.6b00243. Epub 2016 Jun 22.
• We have developed a general methodology to produce bivalent kinase inhibitors for c-Src that interact with the SH2 and ATP binding pockets. Our approach led to a highly selective bivalent inhibitor of c-Src. We demonstrate impressive selectivity for c-Src over homologous kinases. Exploration of the
• PMID 27266260

Japanese Journal

• Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase

• Biological and Pharmaceutical Bulletin 38(11), 1809-1816, 2015
• NAID 130005106378

• Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer

• Experimental Cell Research 322(1), 168-177, 2014-03-10
• NAID 120005517858

• Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection

• Immunity 40(2), 225-234, 2014-02
• NAID 120005425984

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★リンクテーブル★

リンク元	「Srcチロシンキナーゼ」「Src-family kinase」「Src protein-tyrosine kinase」「Src kinase」
関連記事	「kinase」「S」「Sr」

「Srcチロシンキナーゼ」

　　[★]

英

Src tyrosine kinase

関

Srcファミリーキナーゼ、Srcキナーゼ、Srcファミリーチロシンキナーゼ、Srcタンパク質チロシンキナーゼ

「Src-family kinase」

　　[★]

Srcファミリーキナーゼ

関

SFK、Src kinase、Src protein-tyrosine kinase、Src tyrosine kinase、Src-family tyrosine kinase

「Src protein-tyrosine kinase」

　　[★]

• Srcタンパク質チロシンキナーゼ

関

Src kinase、Src tyrosine kinase、Src-family kinase、Src-family tyrosine kinase

「Src kinase」

　　[★]

Srcキナーゼ

関

Src protein-tyrosine kinase、Src tyrosine kinase、Src-family kinase、Src-family tyrosine kinase

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「S」

　　[★]

• セリン serine
• 胸骨上縁

　 　

「Sr」

　　[★] ストロンチウム strontium