primary glucocorticoid resistance

原発性糖質コルチコイド不応症

WordNet

1. any mechanical force that tends to retard or oppose motion
2. the capacity of an organism to defend itself against harmful environmental agents; "these trees are widely planted because of their resistance to salt and smog"
3. the action of opposing something that you disapprove or disagree with; "he encountered a general feeling of resistance from many citizens"; "despite opposition from the newspapers he went ahead" (同)opposition
4. (psychiatry) an unwillingness to bring repressed feelings into conscious awareness
5. group action in opposition to those in power
6. the military action of resisting the enemys advance; "the enemy offered little resistance"
7. the degree of unresponsiveness of a disease-causing microorganism to antibiotics or other drugs (as in penicillin-resistant bacteria)
8. of first rank or importance or value; direct and immediate rather than secondary; "primary goals"; "a primary effect"; "primary sources"; "a primary interest"
9. a preliminary election where delegates or nominees are chosen (同)primary_election
10. one of the main flight feathers projecting along the outer edge of a birds wing (同)primary feather, primary quill
11. (astronomy) a celestial body (especially a star) relative to other objects in orbit around it
12. not derived from or reducible to something else; basic; "a primary instinct"
13. a steroid hormone that is produced by the adrenal cortex of animals; affects functioning of gonads and has anti-inflammatory activity

PrepTutorEJDIC

1. 〈U〉〈C〉(…に)『抵抗』(『反抗』)『すること』;(…を)『こらえること』《+『to』(『against』)+『名』(do『ing』)》 / 〈U〉(病気などに対する)『抵抗力』《+『against』(『to』)+『名』》 / 〈U〉〈C〉(またresistance movement)(権力・圧制に対する)抵抗運動,レジスタンス / 〈U〉(空気の)抵抗;(電気の)抵抗
2. 『第一の』,『主要な』 / 『初期の』,『初等の』,初級の / 『根本的な』,基本的な,本来の,直接的な / 《名詞の前にのみ用いて》(回路・コイル・巻き・電流などが)一次の / 原色(三原色の一つ) / 《米》=primary election

UpToDate Contents

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• 1. 副腎アンドロゲン過剰症 adrenal hyperandrogenism
• 2. 副腎不全の稀な原因 unusual causes of adrenal insufficiency
• 3. 原発性巣状分節性糸球体硬化症の治療 treatment of primary focal segmental glomerulosclerosis
• 4. ステロイド抵抗性喘息 glucocorticoid resistant asthma
• 5. 低カリウム血症を合併した高血圧症へのアプローチ approach to the patient with hypertension and hypokalemia

English Journal

• Network-based expression analysis reveals key genes related to glucocorticoid resistance in infant acute lymphoblastic leukemia.

• Mousavian Z1, Nowzari-Dalini A2, Stam RW3, Rahmatallah Y4, Masoudi-Nejad A5.
• Cellular oncology (Dordrecht).Cell Oncol (Dordr).2017 Feb;40(1):33-45. doi: 10.1007/s13402-016-0303-7. Epub 2016 Oct 31.
• PMID 27798768

• DUSP1 Maintains IRF1 and Leads to Increased Expression of IRF1-dependent Genes: A MECHANISM PROMOTING GLUCOCORTICOID INSENSITIVITY.

• Shah S1, King EM1, Mostafa MM1, Altonsy MO1,2, Newton R3.
• The Journal of biological chemistry.J Biol Chem.2016 Oct 7;291(41):21802-21816. Epub 2016 Aug 22.
• PMID 27551049

• Pyr3, a TRPC3 channel blocker, potentiates dexamethasone sensitivity and apoptosis in acute lymphoblastic leukemia cells by disturbing Ca(2+) signaling, mitochondrial membrane potential changes and reactive oxygen species production.

• Abdoul-Azize S1, Buquet C2, Vannier JP3, Dubus I2.
• European journal of pharmacology.Eur J Pharmacol.2016 Aug 5;784:90-8. doi: 10.1016/j.ejphar.2016.05.014. Epub 2016 May 12.
• PMID 27179991

Japanese Journal

• 症例報告 インスリン抵抗性を背景としステロイド治療と糖質過剰摂取が誘因となり発症した続発性低カリウム血症性周期性四肢麻痺の1例

• 日本プライマリ・ケア連合学会誌 = An official journal of the Japan Primary
• NAID 40021059792

• A Case of Primary Glucocorticoid Resistance

• Nagoya journal of medical science 58(3/4), 143-147, 1995-12
• NAID 110000023125

• Regulation of Mn-superoxide Dismutase Expression in Glomerular Cells

• 日本小児腎臓病学会雑誌 8(1), 57-63, 1995
• NAID 130004495426

Related Links

• Primary Generalized Glucocorticoid Resistance

At the cellular level, the actions of glucocorticoids are mediated by a 94-kd protein, the glucocorticoid receptor (GR). The human (h) GR belongs to the steroid/thyroid/retinoic acid superfamily of nuclear receptors and functions as a ligand-dependent transcription factor that regulates the expression of ...

• Q&A: Primary generalized glucocorticoid resistance

Other Sections What is 'Primary Generalized Glucocorticoid Resistance' (PGGR)? What biological processes underlie this "resistance" to cortisol? What are these manifestations of hyperandrogenism and ...

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★リンクテーブル★

リンク元	「原発性糖質コルチコイド不応症」
関連記事	「primary」「glucocorticoid resistance」「glucocorticoid」「resistance」

「原発性糖質コルチコイド不応症」

　　[★]

英

primary glucocorticoid resistance

同

原発性グルココルチコイド不応症、原発性コルチゾール抵抗症 原発性コルチゾール不応症 primary cortisol resistance

関

糖質コルチコイド

「primary」

　　[★]

• adj.

• 一次の、第一次の、主要な、(化学)第一級の、一級の、初生の、(病名)原発性の、原発の、プライマリーの

関

cardinal、chief、first-order、foremost、main、mainly、major、master、primarily、principal、principally

　 　 　 　 　 　

「glucocorticoid resistance」

　　[★] 糖質コルチコイド不応症

「glucocorticoid」

　　[★] 糖質コルチコイド 　

「resistance」

　　[★]