前駆B細胞腫瘍
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis.
- Dardaei L1, Longobardi E, Blasi F.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Mar 11;111(10):E896-905. doi: 10.1073/pnas.1321200111. Epub 2014 Feb 27.
- Pbx-regulating protein-1 (Prep1) is a tumor suppressor, whereas myeloid ecotropic viral integration site-1 (Meis1) is an oncogene. We show that, to perform these activities in mouse embryonic fibroblasts, both proteins competitively heterodimerize with pre-B-cell leukemia homeobox-1 (Pbx1). Meis1 al
- PMID 24578510
- A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells.
- Jamieson SM1, Gu Y2, Manesh DM3, El-Hoss J3, Jing D3, Mackenzie KL3, Guise CP1, Foehrenbacher A2, Pullen SM2, Benito J4, Smaill JB1, Patterson AV1, Mulaw MA5, Konopleva M4, Bohlander SK6, Lock RB3, Wilson WR7.
- Biochemical pharmacology.Biochem Pharmacol.2014 Mar 1;88(1):36-45. doi: 10.1016/j.bcp.2013.12.019. Epub 2014 Jan 13.
- Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) metabolises steroid hormones, prostaglandins and xenobiotics, and activates the dinitrobenzamide mustard prodrug PR-104A by reducing it to hydroxylamine PR-104H. Here, we describe a functional assay for AKR1C3 in cells using the fluorogenic probe coumbe
- PMID 24434189
- Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia.
- Joshi I1, Yoshida T1, Jena N2, Qi X1, Zhang J3, Van Etten RA4, Georgopoulos K1.
- Nature immunology.Nat Immunol.2014 Mar;15(3):294-304. doi: 10.1038/ni.2821. Epub 2014 Feb 9.
- Deletion of the DNA-binding domain of the transcription factor Ikaros generates dominant-negative isoforms that interfere with its activity and correlate with poor prognosis in human precursor B cell acute lymphoblastic leukemia (B-ALL). Here we found that conditional inactivation of the Ikaros DNA-
- PMID 24509510
Japanese Journal
- Distinct signaling requirements for Dμ selection, IgH allelic exclusion, pre-B cell transition and tumor suppression in B cell progenitors
- High Frequency of Leukemic Lymphomas with Osteosarcomas but No Myeloid Leukemias in C3H Mice after ^<239>Pu Citrate Injection : High Frequency of Leukemic Lymphomas with Osteosarcomas but No Myeloid Leukemias in C3H Mice after ^<239>Pu Citrate Injection
- Non‐T‐cell lymphoblastic lymphomaの1小児例
Related Links
- Abstract A late pre-B-cell leukemia model in the rat, the LAMA tumor, is described. A mouse monoclonal antibody (HIS30) was developed against LAMA cells. HIS30 reacts with a membrane antigen in tumor tissue ...
- Summary Proteasome inhibitor (PI) resistance mechanisms in multiple myeloma (MM) remain controversial. We report the existence of a progenitor organization in primary MM that recapitulates maturation stages between B cells and ...
Related Pictures
★リンクテーブル★
[★]
- 英
- pre-B cell tumor
[show details]
[★]
- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
[★]
[★]
[★]
- 10の-12乗
- 関
- pico
[★]
細胞