porcine reproductive and respiratory syndrome

ブタ生殖器呼吸器症候群、ブタ繁殖・呼吸障害症候群

関

PRRS

WordNet

1. a pattern of symptoms indicative of some disease
2. a complex of concurrent things; "every word has a syndrome of meanings"
3. pertaining to respiration; "respiratory assistance"
4. a breathing device for administering long-term artificial respiration (同)inhalator

PrepTutorEJDIC

1. 《語・句・節を対等に結んで》…『と』…,…や…,および / 《数詞を結合して》…『足す』…,…に加えて / …『しかも』…,…して,同時に… / 《時間的に》『そして』,それから,すると(and then) / 《当然の帰結として》…『ので』,…だから(and so) / 《おもに話》《命令文などの後で》『そうすれば』,そうしたら / 《追加・強調して》それに,しかも / 《対照的な内容を導いて》ところが,しかし(but) / 《譲歩的に》それなのに,それでいながら / 《A and Bで一体の関係を表して》《単数扱い》 / 《同一語を反復して多数・継続などを表して》 / 《同一の複数名詞を結合して変化・種類などを表して》 / 《話》《「形容詞+and+形容詞」の形で前の形容詞が後に副詞的に働く》 / 《話》《「動詞come, goなど+and+動詞」の形でandとその後の動詞が不定詞の働きをして》 / 《「動詞+and+動詞」の形で後の動詞が現在分詞の意を表して》 / 《話》《文頭において前の質問・意見などに同意を示して》そうとも,そして(Yes!and) / 《話》《文頭に置いて驚き・疑念・非難などを表して》ほんとうに;…なのに
2. (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
3. 呼吸の,呼吸作用の,呼吸のための
4. 《米》人工呼吸装置 / (一般に)マスク;防毒マスク
5. (次にくる語の発音が母音で始まるときに用いる) / (子音[h]で始まり第1音節に強勢のない語の場合はanを用いることがある.ただし,この場合は[h]を発音しない)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/10 02:28:19」(JST)

wiki en

[Wiki en表示]

Arterivirus
Virus classification
Group:	Group IV ((+)ssRNA)
Order:	Nidovirales
Family:	Arteriviridae
Genus:	Arterivirus
Species
Porcine reproductive and respiratory syndrome virus

For the Marvel Comics Superhero, see Blue Ear (Marvel Comics).

Porcine reproductive and respiratory syndrome virus (PRRSV), also known as blue-ear pig disease (in Chinese, zhū láněr bìng 豬藍耳病), is a virus that causes a disease of pigs, called porcine reproductive and respiratory syndrome (PRRS). This economically important, pandemic disease causes reproductive failure in breeding stock and respiratory tract illness in young pigs. Initially referred to as "mystery swine disease" and "mystery reproductive syndrome," it was first reported in 1987 in North America (2) and Central Europe (3). The disease costs the United States swine industry around $600 million annually.

Classification

PRRSV is a small, enveloped RNA virus. It contains a single-stranded, positive-sense, RNA genome with a size of approximately 15 kilobases. The genome contains nine open reading frames (Meulenburg et al., 1992, Lee and Yoo, 2005).

PRRSV is a member of the genus Arterivirus, family Arteriviridae, order Nidovirales. The three other members of the genus Arterivirus are: equine arteritis virus, simian hemorrhagic fever virus, and lactate dehydrogenase elevating virus (4-5).

Strains

The two prototype strains of PRRSV are the North American strain, VR-2332, and the European strain, the Lelystad virus (LV). The European and North American PRRSV strains cause similar clinical symptoms, but represent two distinct viral genotypes whose genomes diverge by approximately 40% (6), thus creating a veil of mystery about the origin of this virus. The genetic variation among the viruses isolated from different places (7-8) increases the difficulty of developing vaccines against it. Similarly, maintaining diagnostic PCR detection assays is difficult due to the high mutation rate of this virus, see Risk of Missed PRRS PCR Detection.

Clinical signs

Subclinical infections are common, with clinical signs occurring sporadically in a herd. Clinical signs include reproductive failure in sows such as abortions and giving birth to stillborn or mummified fetuses, and cyanosis of the ear and vulva. In neonatal pigs, the disease causes respiratory distress, with increased susceptibility to respiratory infections such as Glasser's disease.

See also

• Risk of Missed PRRS PCR Detection
• Animal viruses
• Virology
• Nidovirales

References

• Benfield D, Collins J, Dee S, Halbur P, Joo H, Lager K, et al. Porcine reproductive and respiratory syndrome. In: Straw BE, D’Allaire S, Mengeling WL, Taylor DJ, editors. Diseases of the swine. 8th ed. Ames, Iowa: Iowa State University Press; 1999. p. 201–32.
• Collins J, Benfield D, Christianson W, Harris L, Hennings J, Shaw D, et al. Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs. J Vet Diagn Invest 1992;4:117–26
• Wensvoort G. Lelystad virus and the porcine epidemic abortion and respiratory syndrome. Vet Res 1993;24:117–24
• Cavenagh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol 1997;142:629–33
• Thiel HJ, Meyers G, Stark R, Tautz N, Rumenapf T, Unger G, Conzelmann KK., Molecular characterization of positive-strand RNA viruses: pestiviruses and the porcine reproductive and respiratory syndrome virus (PRRSV). Arch Virol Suppl. 1993;7:41-52
• Nelsen C, Murtaugh M, Faaberg K. Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents. J Virol 1999;73:270–80
• Kapur V, Elam MR, Pawlovich TM, Murtaugh MP. Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States. J Gen Virol. 1996 Jun;77 ( Pt 6):1271-6
• Meng XJ, Paul PS, Halbur PG, Morozov I.Sequence comparison of open reading frames 2 to 5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virus. J Gen Virol. 1995 Dec;76 ( Pt 12):3181-8
• Barboza, David. Chinese Pig Virus Causes Concern Around the Globe. The New York Times. August 15, 2007.
• Meulenberg, J. J.; Hulst, M. M.; de Meijer, E. J.; Moonen, P. L.; den Besten, A.; de Kluyver, E. P.; Wensvoort, G., and Moormann, R. J. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology. 1993 Jan; 192(1):62-72.
• Lee, C. and Yoo, D. Cysteine residues of the porcine reproductive and respiratory syndrome virus small envelope protein are non-essential for virus infectivity. J Gen Virol. 2005 Nov; 86(Pt 11):3091-6.

External links

• Porcine Reproductive and Respiratory Syndrome Virus Database
• New York Times article on the 2007 epidemic
• "Europe's piglets die in mystery plague". New Scientist. May 4, 1991. http://www.newscientist.com/article/mg13017671.900-europes-piglets-die-in-mystery-plague-.html. Retrieved 2007-06-28.
• Animal viruses
• PRRS Research Award for PRRS Eradication
• PADRAP Production Animal Disease Risk Assessment Program PRRS Risk Survey
• Animal viruses
• The latest new features on this swine disease, created by Scott A. Dee
• PRRS, from ThePigSite disease guide

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

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• 5. 男性不妊症の治療 treatment of male infertility

English Journal

• Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate.

• Cottam EM, Maier HJ, Manifava M, Vaux LC, Chandra-Schoenfelder P, Gerner W, Britton P, Ktistakis NT, Wileman T.SourceBiomedical Research Centre; Faculty of Health; School of Medicine; University of East Anglia; Norwich, UK.
• Autophagy.Autophagy.2011 Nov 1;7(11). [Epub ahead of print]
• Autophagy is a cellular response to starvation which generates autophagosomes to carry cellular organelles and long-lived proteins to lysosomes for degradation. Degradation through autophagy can provide an innate defence against virus infection, or conversely autophagosomes can promote infection by
• PMID 21799305

• Porcine reproductive and respiratory syndrome virus (PRRSV) influences infection dynamics of porcine circovirus type 2 (PCV2) subtypes PCV2a and PCV2b by prolonging PCV2 viremia and shedding.

• Sinha A, Shen HG, Schalk S, Beach NM, Huang YW, Meng XJ, Halbur PG, Opriessnig T.SourceDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S. 16th Street, Ames, IA 50011, USA.
• Veterinary microbiology.Vet Microbiol.2011 Sep 28;152(3-4):235-46. Epub 2011 May 11.
• The objective of this study was to determine the effect of porcine reproductive and respiratory syndrome virus (PRRSV) infection on porcine circovirus type 2 (PCV2) subtypes a (PCV2a) or b (PCV2b) viremia and shedding characteristics in oral, nasal and fecal samples in experimentally infected pigs.
• PMID 21641124

Japanese Journal

• Genetic analysis of ORF5 in porcine reproductive and respiratory syndrome virus in Japan

• Iseki Hiroshi,Takagi Michihiro,Miyazaki Ayako [他]
• Microbiology and
• NAID 40018735609

• 豚サーコウイルス2型および豚繁殖・呼吸障害症候群ウイルスに感染した肥育豚からの Cryptosporidium parvum pig genotype II と Cryptosporidium suis の検出

• 油井 武,芝原 友幸,河本 麻理子,山品 恒郎,吉田 輝美,福田 昌治,渡辺 喜正,久保 正法
• 日本獣医師会雑誌 = Journal of the Japan Veterinary Medical Association 63(1), 61-68, 2010-01-20
• NAID 10026516249

Related Links

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豚繁殖・呼吸障害症候群(porcine reproductive and respiratory syndrome). 牛 馬 めん羊山羊 豚 家きん ... アルテリウイルス科、アルテリウイルス属、豚繁殖・呼吸障害 症候群ウイルス（porcine reproductive and respiratory syndrome virus）。ゲノムは単 鎖 ...

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★リンクテーブル★

リンク元	「ブタ生殖器呼吸器症候群」「ブタ繁殖・呼吸障害症候群」「PRRS」
拡張検索	「porcine reproductive and respiratory syndrome virus」
関連記事	「respiratory」「reproductive」「porcine」「syndrome」

「ブタ生殖器呼吸器症候群」

　　[★]

英

porcine reproductive and respiratory syndrome、PRRS

関

ブタ繁殖・呼吸障害症候群

「ブタ繁殖・呼吸障害症候群」

　　[★]

英

porcine reproductive and respiratory syndrome

関

ブタ生殖器呼吸器症候群

「PRRS」

　　[★]

ブタ生殖器呼吸器症候群

関

porcine reproductive and respiratory syndrome

「porcine reproductive and respiratory syndrome virus」

　　[★]

• ブタ繁殖・呼吸障害症候群ウイルス、ブタ生殖器呼吸器症候群ウイルス

関

Lelystad virus、PRRSV

「respiratory」

　　[★]

• adj.

• 呼吸の、呼吸器の、呼吸性の

関

breath、breathe、breathing、respiration、respiratory mechanics、respiratory organ、respiratory tract

　 　

「reproductive」

　　[★]

• adj.

• 生殖の、生殖性の

関

generative、genital、reproduction

　

「porcine」

　　[★]

• ブタの

関

pig、swine

　 　

「syndrome」

　　[★]

• n.

• 症候群